PROT-HISPRA

HIgh Speed PRoteomics Analysis (Prot-HiSPRA): Solving the bottlenecks of proteomics technologies for time sensitive proteome driven medical decisions

Coordinatore	MEDIZINISCHE UNIVERSITAET WIEN    more  Organization address address: SPITALGASSE 23 city: WIEN postcode: 1090 contact info Titolo: Prof. Nome: Rainer Cognome: Schmid Email: send email Telefono: +43 1 40400 5375 Fax: +43 1 40400 5389
Nazionalità Coordinatore	Austria [AT]
Totale costo	3˙212˙398 €
EC contributo	2˙536˙246 €
Programma	FP7-HEALTH Specific Programme "Cooperation": Health
Code Call	FP7-HEALTH-2011-single-stage
Funding Scheme	CP-FP
Anno di inizio	2011
Periodo (anno-mese-giorno)	2011-10-01   -   2015-03-31

 Partecipanti

#	participant	country	role	EC contrib. [€]
1	MEDIZINISCHE UNIVERSITAET WIEN  Organization address address: SPITALGASSE 23 city: WIEN postcode: 1090 contact info Titolo: Prof. Nome: Rainer Cognome: Schmid Email: send email Telefono: +43 1 40400 5375 Fax: +43 1 40400 5389	AT (WIEN)	coordinator	1˙325˙422.60
2	MAYLAB ANALYTICAL INSTRUMENTS GMBH  Organization address address: Postgasse 11 city: Vienna postcode: 1010 contact info Titolo: Mr. Nome: Hans Cognome: Mayrhofer Email: send email Telefono: +43 1 786 42 58 20 Fax: +43 1 786 42 58 50	AT (Vienna)	participant	380˙960.00
3	THE RUSSIAN ACADEMY OF SCIENCES INSTITUTION INSTITUTE FOR ENERGY PROBLEMS OF CHEMICAL PHYSICS OF RAS  Organization address address: LENINSKY PROSPEKT 38 BLD 2 city: MOSKVA postcode: 119334 contact info Titolo: Ms. Nome: Tatiana Cognome: Nikitina Email: send email Telefono: +7 499 1378331 Fax: +7 499 1378258	RU (MOSKVA)	participant	247˙712.00
4	DEBRECENI EGYETEM  Organization address address: EGYETEM TER 1 city: DEBRECEN postcode: 4032 contact info Titolo: Mr. Nome: Zoltán Cognome: Pozsonyi Email: send email Telefono: +36 52 51 2759 Fax: +36 52 51 2781	HU (DEBRECEN)	participant	214˙200.00
5	BIA SEPARATIONS DOO  Organization address address: MIRCE 21 city: AJDOVSCINA postcode: 5270 contact info Titolo: Ms. Nome: Jana Cognome: Kuzmanic Email: send email Telefono: 38659699500 Fax: 38659699599	SI (AJDOVSCINA)	participant	209˙480.00
6	DI ANDREAS MOSER RTD SERVICES -RTDS  Organization address address: KIRSCHENTALGASSE 10 TOP 1 city: INNSBRUCK postcode: 6020 contact info Titolo: Mr. Nome: Andreas Cognome: Moser Email: send email Telefono: +43 664 8333569 Fax: +43 1 890534515	AT (INNSBRUCK)	participant	154˙080.00
7	CENTRE OF EXCELLENCE FOR LIFE SCIENCES LTD  Organization address address: QUORUM 16 city: NEWCASTLE UPON TYNE postcode: NE12 8BX contact info Titolo: Ms. Nome: Catharine Cognome: Little Email: send email Telefono: +44 191 269 6894	UK (NEWCASTLE UPON TYNE)	participant	4˙392.34

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 Obiettivo del progetto (Objective)

'The main objective of the proposed collaborative project Prot-HiSPRA is to remove time-consuming bottlenecks of existing proteomics technologies (sample preparation, fractionation, proteolysis, separation, data collection, and data mining) and bring the proteome driven analysis into time sensitive clinical practice. Prot-HiSPRA is an objective-driven research project and it aims at generating new knowledge and new technologies which will improve the European competitiveness in the field of applied proteomics. Prot-HiSPRA is planned for the duration of 36 months which is necessary in order to ensure a high-quality validation of the developed high-throughput methodologies. A strong participation of SMEs (partner 2 – MAYLAB, partner 3 – CELS - left the onsortium, partner 6 – RTDs, partner 7 - BIA) will ensure strong innovation and exploitation during HiSPRA. Research activities in the Prot-HiSPRA program can be divided into a technological core project that is tailored to significantly improve on technologies in the fields of proteomics, bioinformatics, and integrated biology. Analytical methods developed with the Prot-HiSPRA project will be exemplified by applying for analysis of clinical samples originating from in vitro fertilization (IVF) procedures. During the IVF process, especially at the moment when decisions are made which embryo can be implanted, decisions must be made so that the process has the greatest chance for success. To further elevate pregnancy rates for IVF a non-invasive, rapid, and robust methods for judging the embryos status is urgently needed to examine the embryos´ proteome. These methods could not only be applied in the described field of reproductive medicine but also in any the other fields of clinical analysis where fast and reliable diagnosis on a proteomic basis could be made available.'