MICROBIAL SENSING
Dissecting a new mechanisms of bacterial cell-cell communication
| Coordinatore | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
Organization address
address: Rue Michel -Ange 3 contact info |
| Nazionalità Coordinatore | France [FR] |
| Totale costo | 100˙000 € |
| EC contributo | 100˙000 € |
| Programma | FP7-PEOPLE
Specific programme "People" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013) |
| Code Call | FP7-PEOPLE-2011-CIG |
| Funding Scheme | MC-CIG |
| Anno di inizio | 2011 |
| Periodo (anno-mese-giorno) | 2011-10-01 - 2015-09-30 |
Partecipanti
| # | ||||
|---|---|---|---|---|
| 1 |
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
Organization address
address: Rue Michel -Ange 3 contact info |
FR (PARIS) | coordinator | 100˙000.00 |
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Obiettivo del progetto (Objective)
'For many years, bacteria have been considered very simple organisms mostly studied in the context of single cells. However, recent discoveries revealed the ability of bacteria to develop complex communities. The study of bacterial communities is of biomedical and ecological importance as the formation of highly organized multicellular structures such as biofilms and fruiting bodies render infectious bacteria resistant to antibiotics and are very difficult to treat. Essential for biofilm and fruiting body formation is the ability of bacterial cells to communicate with each other. Recent observations on the model system Myxococcus xanthus suggest the existence of a previously undiscovered mechanism of bacterial cell-cell communication. Very likely, M. xanthus shares its way of cell-cell communication with other bacterial species also forming multicellular structures, including human pathogens. The proposed study will i) focus on the investigation of the mechanisms responsible of cell-cell communications; ii) take advantage of innovative techniques and integrate genetic, biochemical and cellular approaches; iii) open new insights in the knowledge of bacterial multicellularity.'