MODNANOTOX

"Modelling nanoparticle toxicity: principles, methods, novel approaches"

Coordinatore	THE UNIVERSITY OF BIRMINGHAM    more  Organization address address: Edgbaston city: BIRMINGHAM postcode: B15 2TT contact info Titolo: Ms. Nome: May Cognome: Chung Email: send email Telefono: 441214000000 Fax: 441214000000
Nazionalità Coordinatore	United Kingdom [UK]
Sito del progetto	http://www.birmingham.ac.uk/generic/modnanotox
Totale costo	1˙279˙137 €
EC contributo	999˙899 €
Programma	FP7-NMP Specific Programme "Cooperation": Nanosciences, Nanotechnologies, Materials and new Production Technologies
Code Call	FP7-NMP-2010-EU-USA
Funding Scheme	CP-FP
Anno di inizio	2011
Periodo (anno-mese-giorno)	2011-11-01   -   2013-10-31

 Partecipanti

#	participant	country	role	EC contrib. [€]
1	THE UNIVERSITY OF BIRMINGHAM  Organization address address: Edgbaston city: BIRMINGHAM postcode: B15 2TT contact info Titolo: Ms. Nome: May Cognome: Chung Email: send email Telefono: 441214000000 Fax: 441214000000	UK (BIRMINGHAM)	coordinator	382˙465.00
2	ROSKILDE UNIVERSITET  Organization address address: Universitetsvej 1 city: ROSKILDE postcode: 4000 contact info Titolo: Mr. Nome: Bjarne Cognome: Clausen Email: send email Telefono: +45 46 74 22 11 Fax: +45 46 74 30 11	DK (ROSKILDE)	participant	227˙828.00
3	EIDGENOESSISCHE ANSTALT FUR WASSERVERSORGUNG ABWASSERREINIGUNG UND GEWAESSERSCHUTZ  Organization address address: UEBERLANDSTRASSE 133 city: DUEBENDORF postcode: 8600 contact info Titolo: Ms. Nome: Laura Cognome: Klein Email: send email Telefono: +41 44 823 5388 Fax: +41 44 823 5818	CH (DUEBENDORF)	participant	153˙805.00
4	IN SILICO TOXICOLOGY GMBH  Organization address address: ALTKIRCHERSTRASSE 4 city: BASEL postcode: 4054 contact info Nome: Christoph Cognome: Helma Email: send email Telefono: +41 774339164	CH (BASEL)	participant	125˙610.00
5	EIDGENOESSISCHE MATERIALPRUEFUNGS- UND FORSCHUNGSANSTALT  Organization address address: Ueberlandstrasse 129 city: DUEBENDORF postcode: 8600 contact info Titolo: Ms. Nome: Heidi Cognome: Leutwyler Email: send email Telefono: +41 44 823 4591 Fax: +41 44 821 62 44	CH (DUEBENDORF)	participant	110˙191.00
6	UNIVERSITY OF NEBRASKA  Organization address address: Holdrege Street 3835 city: LINCOLN postcode: 68583 contact info Titolo: Ms. Nome: Suzan Cognome: Lund Email: send email Telefono: +1402 472 1930 Fax: +402 472 9323	US (LINCOLN)	participant	0.00

Mappa

 Word cloud

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 Obiettivo del progetto (Objective)

'ModNanoTox will develop a number of well-documented and technically advanced models describing the behaviour of engineered nanoparticles in organisms and the environment. Background to these models will be a thoroughly documented database, constructed based on: (1) an advanced evaluation of physicochemical properties of nanoparticles and in silico modelling of their reactivity; and (2) assessment of the characterisation methodologies as well as toxicity protocols used to develop biological responses in toxicological studies. At the next level whole datasets will be evaluated for internal consistency and then compared with other relevant sets. The evaluation stage will be followed by development of toxicity models based at the individual organism level, using statistical and mechanistic models, in parallel with models predicting environmental fate. The toxicity and fate models will be integrated in mechanistic models to predict the long term risks of engineered nanoparticles for populations under realistic environmental conditions. The risk assessment models will be developed in close collaboration with appropriate stakeholders and end users to ensure their suitability for practical use in relevant legislative contexts.'

Introduzione (Teaser)

Engineered nanoparticles (ENPs) now form the basis of a myriad of products and devices across numerous sectors. An EU-funded study has laid the groundwork and pointed the way to descriptive models to predict toxicity.