CAD-BONE

Patient-specific predictions for bone treatments

Coordinatore	UNIVERSIDAD DE ZARAGOZA    more  Organization address address: CALLE PEDRO CERBUNA 12 city: Zaragoza postcode: 50009 contact info Titolo: Dr. Nome: Jose Manuel Cognome: Garcia-Aznar Email: send email Telefono: 34976761000
Nazionalità Coordinatore	Spain [ES]
Totale costo	582˙790 €
EC contributo	582˙790 €
Programma	FP7-PEOPLE Specific programme "People" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013)
Code Call	FP7-PEOPLE-2011-IAPP
Funding Scheme	MC-IAPP
Anno di inizio	2012
Periodo (anno-mese-giorno)	2012-01-01   -   2015-12-31

 Partecipanti

#	participant	country	role	EC contrib. [€]
1	UNIVERSIDAD DE ZARAGOZA  Organization address address: CALLE PEDRO CERBUNA 12 city: Zaragoza postcode: 50009 contact info Titolo: Dr. Nome: Jose Manuel Cognome: Garcia-Aznar Email: send email Telefono: 34976761000	ES (Zaragoza)	coordinator	187˙601.00
2	MATERIALISE NV  Organization address address: TECHNOLOGIELAAN 15 city: HEVERLEE postcode: 3001 contact info Titolo: Dr. Nome: Roel Cognome: Wirix-Speetjens Email: send email Telefono: 3216396281	BE (HEVERLEE)	participant	224˙587.00
3	KATHOLIEKE UNIVERSITEIT LEUVEN  Organization address address: Oude Markt 13 city: LEUVEN postcode: 3000 contact info Titolo: Ms. Nome: Sofie Cognome: Heroes Email: send email Telefono: +32 16 329979 Fax: +32 16 326515	BE (LEUVEN)	participant	170˙602.00

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 Obiettivo del progetto (Objective)

'CAD-BONE addresses a multidisciplinary research that will transform current technology by radically improving the development of patient-specific computer models for the modelling of bone remodelling/healing to predict short and long-term bone response after surgical interventions. Specifically, CAD-BONE will combine image processing, musculoskeletal modelling tools, finite element analyses and bone remodelling/healing algorithms to provide an understanding of the individual functional outcome of patient treatments from standard clinical radiographs. Although already developed and broadly in use, these computer technologies and methods are yet to be combined and integrated to create a computer tool with a predictive purpose. To successfully achieve this objective different scientific and technological challenges will be faced. Firstly, the automatic construction of patient-specific finite element models of specific bones (including geometries, loads and boundary conditions). Secondly, The improvement of current bone remodelling/healing models, which are very slow, labour-intesive and costly processes, in order to achieve accurate near real-time results; to do so, different strategies based on model reduction techniques will be explored). And, finally, the quantitative validation of these patient-specific models. Such a validation will require a quantitative comparison between real bone density distributions obtained by computer tomography (CT) and those predicted from computer simulations. Therefore, we expect that CAD-BONE can lead to a preliminary tool for the prediction of bone morphological changes resulting from changes in mechanical loading conditions.'