GIFTS
Genomic and lifestyle predictors of foetal outcome relevant to diabetes and obesity and their relevance to prevention strategies in South Asian peoples
| Coordinatore | QUEEN MARY UNIVERSITY OF LONDON
Organization address
address: 327 MILE END ROAD contact info |
| Nazionalità Coordinatore | United Kingdom [UK] |
| Sito del progetto | http://www.gifts-project.eu/ |
| Totale costo | 3˙887˙200 € |
| EC contributo | 2˙999˙332 € |
| Programma | FP7-HEALTH
Specific Programme "Cooperation": Health |
| Code Call | FP7-HEALTH-2011-two-stage |
| Funding Scheme | CP-FP-SICA |
| Anno di inizio | 2012 |
| Periodo (anno-mese-giorno) | 2012-02-01 - 2016-01-31 |
Partecipanti
| # | ||||
|---|---|---|---|---|
| 1 |
QUEEN MARY UNIVERSITY OF LONDON
Organization address
address: 327 MILE END ROAD contact info |
UK (LONDON) | coordinator | 693˙416.90 |
| 2 |
DIABETIC ASSOCIATION OF BANGLADESH - DAB
Organization address
address: KAZI NAZRUL ISLAM AVENUE 122 contact info |
BD (DHAKA) | participant | 394˙803.60 |
| 3 |
INSTRUCT AG
Organization address
address: LINDWURMSTRASSE 27 contact info |
DE (MUNCHEN) | participant | 358˙203.62 |
| 4 |
UNIVERSITETET I OSLO
Organization address
address: Problemveien 5-7 contact info |
NO (OSLO) | participant | 343˙549.20 |
| 5 |
BAP HEALTH OUTCOMES RESEARCH SL
Organization address
address: CALLE AZCARRAGA 12 contact info |
ES (OVIEDO) | participant | 240˙602.40 |
| 6 |
COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH
Organization address
address: Anusandhan Bhawan, Rafi Marg 2 contact info |
IN (NEW DEHLI) | participant | 159˙098.40 |
| 7 |
PUBLIC HEALTH FOUNDATION OF INDIA
Organization address
address: "SIRIFORT INSTITUTIONAL AREA, AUGUST KRANTI MARG, PHD HOUSE 4/2, 2ND FLOOR" contact info |
IN (NEW DELHI) | participant | 148˙425.60 |
| 8 |
KING EDWARD MEMORIAL HOSPITAL RESEARCH CENTRE
Organization address
address: "SARDAR MOODLIAR ROAD, RASTA PETH" contact info |
IN (PUNE) | participant | 140˙404.80 |
| 9 |
UNIVERSITY OF EAST LONDON
Organization address
address: Romford Road contact info |
UK (LONDON) | participant | 139˙088.70 |
| 10 |
THE UNIVERSITY OF EXETER
Organization address
address: Northcote House, The Queen's Drive contact info |
UK (EXETER) | participant | 119˙347.20 |
| 11 |
UNIVERSITY OF SOUTHAMPTON
Organization address
address: Highfield contact info |
UK (SOUTHAMPTON) | participant | 105˙177.60 |
| 12 |
BAQAI MEDICAL UNIVERSITY
Organization address
address: PLOT 1 2 II B BLOCK 2 NAZIMABAD 2 contact info |
PK (KARACHI) | participant | 80˙403.60 |
| 13 |
TECHNISCHE UNIVERSITAET DRESDEN
Organization address
address: HELMHOLTZSTRASSE 10 contact info |
DE (DRESDEN) | participant | 28˙202.40 |
| 14 |
HELSINGIN YLIOPISTO
Organization address
address: YLIOPISTONKATU 4 contact info |
FI (HELSINGIN YLIOPISTO) | participant | 16˙203.20 |
| 15 |
LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE
Organization address
address: KEPPEL STREET contact info |
UK (LONDON) | participant | 16˙202.40 |
| 16 |
UNIVERSITY COLLEGE LONDON
Organization address
address: GOWER STREET contact info |
UK (LONDON) | participant | 16˙202.40 |
Mappa
Word cloud
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Obiettivo del progetto (Objective)
'Despite a strong genetic component to diabetes and obesity, the rapidly rising prevalence of these disorders is due to adaptation to a changing environment. The epicentre of the ‘diabetes epidemic’ is in South Asia and this is reflected in the migrant populations in Europe. Current prevention strategies are focused on adult life and target over-nutrition in high-risk adults. However, for many population groups across the globe, these strategies ignore many key principles that underlie the increasing global prevalence of these diseases. A substantial portion of the South Asian people, living in their home countries experience nutrition deprivation, while after migration to Europe, may encounter nutritional abundance resulting in imbalance during their lifecourse. These conditions are of particular importance during foetal and early developmental stages where environmental insults may interact with genetic risk to induce ‘foetal programming’ of adult metabolic disease. Few groups have targeted early life programming as an opportunity for the prevention of diabetes/obesity in childhood and subsequent adult life and there are limited guidelines on this topic. The proposed grant will bring together a unique group of investigators in South Asia (India, Bangladesh and Pakistan) and Europe (UK, Norway, Germany and Finland) with SMEs of complementary expertise (Germany and Spain) combining prevention strategies, state-of-the-art genomics, social sciences and public health that focus on these early life predictors of disease. The major objective behind this collaborative and multi-disciplinary approach is to combine knowledge from the work packages on lifestyle, nutrition and genomics to both inform public health policy through guideline development and design a large-scale pragmatic intervention to prevent the metabolic syndrome, obesity and diabetes in South Asian populations aimed at early life taking into account multi-generational effects.'
Introduzione (Teaser)
The epicentre of the diabetes epidemic is in South Asia and the occurrence of diabetes in migrants from this region is up to six times higher than the European average. New prevention strategies have to address principle causes that underlie the increasing incidence of the disease.