DENFREE
Dengue research Framework for Resisting Epidemics in Europe
| Coordinatore | INSTITUT PASTEUR
Organization address
address: RUE DU DOCTEUR ROUX 25-28 contact info |
| Nazionalità Coordinatore | France [FR] |
| Totale costo | 8˙373˙688 € |
| EC contributo | 5˙999˙062 € |
| Programma | FP7-HEALTH
Specific Programme "Cooperation": Health |
| Code Call | FP7-HEALTH-2011-single-stage |
| Funding Scheme | CP-FP-SICA |
| Anno di inizio | 2012 |
| Periodo (anno-mese-giorno) | 2012-01-01 - 2016-12-31 |
Partecipanti
| # | ||||
|---|---|---|---|---|
| 1 |
INSTITUT PASTEUR
Organization address
address: RUE DU DOCTEUR ROUX 25-28 contact info |
FR (PARIS CEDEX 15) | coordinator | 1˙396˙860.04 |
| 2 |
INSTITUT PASTEUR DU CAMBODGE FOUNDATION
Organization address
address: BOULEVARD MONIVONG 5 contact info |
KH (PHNOM PENH) | participant | 821˙504.20 |
| 3 |
MAHIDOL UNIVERSITY
Organization address
address: RATCHAWITHI ROAD 420/6 contact info |
TH (BANGKOK) | participant | 574˙280.00 |
| 4 |
IMPERIAL COLLEGE OF SCIENCE, TECHNOLOGY AND MEDICINE
Organization address
address: SOUTH KENSINGTON CAMPUS EXHIBITION ROAD contact info |
UK (LONDON) | participant | 429˙791.80 |
| 5 |
FUNDACIO INSTITUT CATALA DE CIENCIES DEL CLIMA
Organization address
address: CALLE BALDIRI REIXAC 2 contact info |
ES (Barcelona) | participant | 399˙304.50 |
| 6 |
UNIVERSITE DE ROUEN
Organization address
address: RUE THOMAS BECKET 1 MONT SAINT AIGNAN contact info |
FR (MONT SAINT AIGNAN CEDEX) | participant | 356˙800.00 |
| 7 |
BERNHARD-NOCHT-INSTITUT FUER TROPENMEDIZIN
Organization address
address: BERNHARD NOCHT STRASSE 74 contact info |
DE (HAMBURG) | participant | 336˙560.00 |
| 8 |
AMPTEC GMBH
Organization address
address: KOENIGSTRASSE 4A contact info |
DE (HAMBURG) | participant | 324˙480.00 |
| 9 |
FUNDACAO DA FACULDADE DE CIENCIAS DA UNIVERSIDADE DE LISBOA
Organization address
address: CAMPO GRANDE EDIFICIO C1 PISO 3 contact info |
PT (LISBOA) | participant | 288˙000.00 |
| 10 |
IPATIMUP - INSTITUTO DE PATOLOGIA EIMUNOLOGIA MOLECULAR DA UNIVERSIDADE DO PORTO PCUP
Organization address
address: RUA DR ROBERTO FRIAS SN contact info |
PT (PORTO) | participant | 267˙600.00 |
| 11 |
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
Organization address
address: Rue Michel -Ange 3 contact info |
FR (PARIS) | participant | 236˙168.00 |
| 12 |
BIOCOMPUTING PLATFORMS LTD OY
Organization address
address: TEKNIIKANTIE 14 contact info |
FI (ESPOO) | participant | 213˙960.00 |
| 13 |
RIOTECH PHARMACEUTICALS LTD
Organization address
address: ALBERT STREET 6 contact info |
UK (CAMBRIDGE) | participant | 204˙480.00 |
| 14 |
INSTITUTO DE MEDICINA TROPICAL PEDRO KOURI
Organization address
address: AUTOPISTA NOVIA MEDIODIA KM 6 1/2 contact info |
CU (LA HABANA) | participant | 109˙273.46 |
| 15 |
INSTITUT LOUIS MALARDE
Organization address
address: rue du 5 mars 1797 contact info |
PF (PAPEETE) | participant | 40˙000.00 |
Mappa
Word cloud
Esplora la "nuvola delle parole (Word Cloud) per avere un'idea di massima del progetto.
Obiettivo del progetto (Objective)
'WHO estimates that one of the main consequences of global warming will be an increased burden of vector-borne diseases. Among these, dengue appears to be particularly problematic, with tens of millions of cases of dengue fever estimated to occur annually, including up to 500,000 cases of the life-threatening dengue hemorrhagic fever/dengue shock syndrome. In recent years, the global burden of dengue disease has been rising dramatically and this prolific increase has been connected to societal changes such as population growth, urbanization and the transport of infected hosts and vectors. In addition, rising temperatures and global climate change may lead to the expansion of the range of major mosquito vectors, extension of the transmission season in areas with currently circulating dengue virus and increase in the mosquito spp. vectorial capacity. Active surveillance to detect in-coming dengue virus (DENV) in regions at the limits of DENV circulation are an important initial step in the prevention of dengue epidemics in Europe. Asymptomatic infections likely play a crucial role in the initial invasion process and DENV transmission and, although hitherto ignored, must be addressed. Using retrospective and prospective data from Asia, the main objectives of the program are (1) to identify key factors determining dengue transmission, outcome of infection and epidemics; (2) the development of novel diagnostic tools to detect asymptomatic infections. We will estimate the risk of DENV spreading to uninfected areas, especially in Southern Europe where susceptible vector exists. The major tools generated will be predictive models that enable specific interventions to reduce epidemic probability and diagnostic methods for surveillance. Inherent in this approach is the belief that improved surveillance and diagnosis of the asymptomatic dengue carriers will contribute to effective intervention, especially during early stages of pathogen invasion into a naïve region.'
Introduzione (Teaser)
Dengue virus (DENV) infection is a major international public health problem. A multidisciplinary approach is needed to reduce the impact of dengue and prevent its extension into new areas.
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