CELLEUROPE
Improving HSCT By Validation Of Biomarkers & Development Of Novel Cellular Therapies
| Coordinatore | UNIVERSITY OF NEWCASTLE UPON TYNE
Organization address
address: Kensington Terrace 6 contact info |
| Nazionalità Coordinatore | United Kingdom [UK] |
| Totale costo | 3˙226˙319 € |
| EC contributo | 3˙226˙319 € |
| Programma | FP7-PEOPLE
Specific programme "People" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013) |
| Code Call | FP7-PEOPLE-2012-ITN |
| Funding Scheme | MC-ITN |
| Anno di inizio | 2012 |
| Periodo (anno-mese-giorno) | 2012-10-01 - 2016-09-30 |
Partecipanti
| # | ||||
|---|---|---|---|---|
| 1 |
UNIVERSITY OF NEWCASTLE UPON TYNE
Organization address
address: Kensington Terrace 6 contact info |
UK (NEWCASTLE UPON TYNE) | coordinator | 920˙805.70 |
| 2 |
UNIVERSITETET I OSLO
Organization address
address: Problemveien 5-7 contact info |
NO (OSLO) | participant | 561˙642.80 |
| 3 |
ALCYOMICS LTD
Organization address
address: BULMAN HOUSE REGENT CENTRE contact info |
UK (NEWCASTLE UPON TYNE) | participant | 250˙652.16 |
| 4 |
MEDIZINISCHE UNIVERSITAET WIEN
Organization address
address: SPITALGASSE 23 contact info |
AT (WIEN) | participant | 240˙201.72 |
| 5 |
KLINIKUM DER UNIVERSITAET REGENSBURG
Organization address
address: FRANZ JOSEF STRAUSS ALLEE 11 contact info |
DE (REGENSBURG) | participant | 222˙068.88 |
| 6 |
MEDIZINISCHE HOCHSCHULE HANNOVER
Organization address
address: Carl-Neuberg-Strasse 1 contact info |
DE (HANNOVER) | participant | 222˙068.88 |
| 7 |
UNIVERSITAETSMEDIZIN GOETTINGEN - GEORG-AUGUST-UNIVERSITAET GOETTINGEN - STIFTUNG OEFFENTLICHEN RECHTS
Organization address
address: Robert-Koch-Strasse 40 contact info |
DE (GOETTINGEN) | participant | 222˙068.88 |
| 8 |
UNIVERZITA KARLOVA V PRAZE
Organization address
address: Ovocny trh 5 contact info |
CZ (PRAHA 1) | participant | 205˙208.52 |
| 9 |
KLINIKUM RECHTS DER ISAR DER TECHNISCHEN UNIVERSITAT MUNCHEN
Organization address
address: ISMANINGER STRASSE 22 contact info |
DE (MUENCHEN) | participant | 190˙800.72 |
| 10 |
MILTENYI BIOTEC GMBH
Organization address
address: FRIEDRICH EBERT STRASSE 68 contact info |
DE (BERGISCH GLADBACH) | participant | 190˙800.72 |
| 11 | MULTIMMUNE GMBH | DE | participant | 0.00 |
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Obiettivo del progetto (Objective)
'Novel transplant regimens are currently being developed to improve beneficial GvL effects and reduce GvHD and infections via several new forms of cellular therapies. This newly emerging supra-disciplinary field of cellular therapy and regenerative medicine is also being used to improve outcomes in autoimmune disease (such as Rheumatoid Arthritis) and cancers. The goal of this research programme is to gain insight into the mechanisms of action of GvL and GvHD in order to improve current therapies and develop and test novel ones via clinical trials and/or animal model experiments. The research is therefore necessarily multidisciplinary including clinical medicine, immunology, genomics, proteomics, molecular biology and pathology. In order to implement cellular therapies across Europe the current EU Directive 2001/83/EC applies. These regulations stipulate that the cellular therapies which are advanced therapeutic medical products (ATMP) must be produced under current Good Manufacturing Practice (cGMP). Not only is there a lack of understanding of GvL vs. GvHD effects but there is also a lack of training in cGMP for both clinical and non-clinical scientists. We aim to re-address these basic current needs, as well as those of industry, which include lack of access to clinical tissue for validation of bio-markers prior to commercialisation.'