IACOBUS

"Diagnosis and Monitoring of Inflammatory and Arthritic diseases using a COmbined approach Based on Ultrasound, optoacoustic and hyperSpectral imaging"

Coordinatore	FRAUNHOFER-GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V    more  Organization address address: Hansastrasse 27C city: MUENCHEN postcode: 80686 contact info Titolo: Ms. Nome: Andrea Cognome: Zeumann Email: send email Telefono: +49 89 1205 2723 Fax: +49 89 1205 7534
Nazionalità Coordinatore	Germany [DE]
Totale costo	3˙837˙268 €
EC contributo	3˙046˙476 €
Programma	FP7-HEALTH Specific Programme "Cooperation": Health
Code Call	FP7-HEALTH-2012-INNOVATION-1
Funding Scheme	CP-FP
Anno di inizio	2013
Periodo (anno-mese-giorno)	2013-01-01   -   2015-12-31

 Partecipanti

#	participant	country	role	EC contrib. [€]
1	FRAUNHOFER-GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V  Organization address address: Hansastrasse 27C city: MUENCHEN postcode: 80686 contact info Titolo: Ms. Nome: Andrea Cognome: Zeumann Email: send email Telefono: +49 89 1205 2723 Fax: +49 89 1205 7534	DE (MUENCHEN)	coordinator	697˙888.00
2	NORSK ELEKTRO OPTIKK AS  Organization address address: SOLHEIMVEIEN 62 A city: LORENSKOG postcode: 1473 contact info Titolo: Mr. Nome: Peter Cognome: Kaspersen Email: send email Telefono: 4767974700 Fax: 4767974900	NO (LORENSKOG)	participant	765˙042.00
3	NORGES TEKNISK-NATURVITENSKAPELIGEUNIVERSITET NTNU  Organization address address: HOGSKOLERINGEN 1 city: TRONDHEIM postcode: 7491 contact info Titolo: Dr. Nome: Lise Cognome: Lyngsnes Randeberg Email: send email Telefono: +47 73594416 Fax: +47 73591441	NO (TRONDHEIM)	participant	564˙648.00
4	VERMON SA  Organization address address: RUE DU GENERAL RENAULT 180 city: TOURS CEDEX 1 postcode: 37038 contact info Titolo: Mr. Nome: Jean-Yves Cognome: Corduan Email: send email Telefono: 33247374278 Fax: 33247381545	FR (TOURS CEDEX 1)	participant	384˙518.00
5	TP21 GMBH  Organization address address: LUISENSTRASSE 14 city: BERLIN postcode: 10117 contact info Titolo: Dr. Nome: Petra Cognome: Zalud Email: send email Telefono: +49 681 390 67 19	DE (BERLIN)	participant	235˙680.00
6	JUSTUS-LIEBIG-UNIVERSITAET GIESSEN  Organization address address: Ludwigstrasse 23 city: GIESSEN postcode: 35390 contact info Titolo: Dr. Nome: Christian Cognome: Veldmann Email: send email Telefono: +49 641 99 12117 Fax: +49 60641 99 12109	DE (GIESSEN)	participant	230˙400.00
7	EKSPLA UAB  Organization address address: SAVANORIU PR 231 city: VILNIUS postcode: 2300 contact info Titolo: Dr. Nome: Andrejus Cognome: Michailovas Email: send email Telefono: 37052649631 Fax: 37052641809	LT (VILNIUS)	participant	168˙300.00

Mappa

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 Obiettivo del progetto (Objective)

'Rheumatoid arthritis (RA) and psoriasis arthritis (PSA) are destructive polyarthritic diseases having high incidence rates worldwide of about 1,5% and 0,5% respectively. Arthritis-related joint destruction leads to disabilities which result in a loss of patient’s quality of life, often include an inability to work and significant costs for healthcare systems. The functional outcome is strongly dependent on the time lag between the onset of the disease and the treatment beginning (ideally < 3-6 months). For early diagnosis allowing to improve the course of this devastating disease, sensitive and accurate diagnostic tools are required. Further, excellent image quality is needed for differentiated diagnosis (osteoarthritis vs RA or PSA) permitting the stratification of patient groups required for enabling a personalized therapeutical approach. Therefore, tools for early, precise and reliable diagnosis being affordable for screenings are of highest importance. Within IACOBUS, we suggest a new multimodal approach combining hyperspectral imaging with ultrasound (US) and optoacoustic (OA) techniques for diagnosis of arthritic diseases in finger joints. The proposed concept will allow the diagnosis and monitoring of arthritis based on imaging of early inflammation-induced hyperperfusion. Hyperspectral overview imaging for identification of suspicious joints will be combined with detailed high-resolution 3D imaging of affected joints (OA/US). Osteochondral information will be provided by high-frequency US while OA imaging will allow the high-sensitivity imaging of microvasculature in inflamed tissue. The consortium consisting of 4 SMEs and 3 academic partners will develop a novel non-invasive image-based diagnostic tool with significantly enhanced sensitivity for early arthritis symptoms and thereby allow to make use of the therapeutical window of opportunities. 50% of the overall project budget will go to SMEs which will ensure the exploitation of the developed platform.'