ACROBAT

Adsorbent carbons for the removal of biologically active toxins

Coordinatore	UNIVERSITY OF BRIGHTON    more  Organization address address: "Lewes Road, Mithras House" city: BRIGHTON postcode: BN2 4AT contact info Titolo: Dr. Nome: Susan Cognome: Sandeman Email: send email Telefono: 144274000000
Nazionalità Coordinatore	United Kingdom [UK]
Totale costo	1˙449˙659 €
EC contributo	1˙449˙659 €
Programma	FP7-PEOPLE Specific programme "People" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013)
Code Call	FP7-PEOPLE-2011-IAPP
Funding Scheme	MC-IAPP
Anno di inizio	2012
Periodo (anno-mese-giorno)	2012-12-01   -   2016-11-30

 Partecipanti

#	participant	country	role	EC contrib. [€]
1	UNIVERSITY OF BRIGHTON  Organization address address: "Lewes Road, Mithras House" city: BRIGHTON postcode: BN2 4AT contact info Titolo: Dr. Nome: Susan Cognome: Sandeman Email: send email Telefono: 144274000000	UK (BRIGHTON)	coordinator	297˙642.00
2	ALBUTEC GMBH  Organization address address: SCHILLINGALLEE 68 city: ROSTOCK postcode: 18057 contact info Titolo: Prof. Nome: Jan Cognome: Stange Email: send email Telefono: 49381128985	DE (ROSTOCK)	participant	295˙244.00
3	Polymerics GmbH - Spezialpolymere - Klebstoffe - Polymercharakterisierung  Organization address address: "Landsberger Alle, 378" city: BERLIN postcode: 12681 contact info Titolo: Mr. Nome: Andre Cognome: Leistner Email: send email Telefono: +49 30 54378343	DE (BERLIN)	participant	215˙464.00
4	UNIVERSITY COLLEGE LONDON  Organization address address: GOWER STREET city: LONDON postcode: WC1E 6BT contact info Titolo: Ms. Nome: Greta Cognome: Borg-Carbott Email: send email Telefono: 442031000000	UK (LONDON)	participant	206˙362.00
5	CARDIFF UNIVERSITY  Organization address address: Newport Road 30-36 city: CARDIFF postcode: CF24 ODE contact info Titolo: Ms. Nome: Eevi Cognome: Laukkanen Email: send email Telefono: +44 29 20870114	UK (CARDIFF)	participant	191˙810.00
6	MAST CARBON INTERNATIONAL LTD  Organization address address: JAYS CLOSE VIABLES city: Basingstoke postcode: RG22 4BA contact info Titolo: Prof. Nome: Stefan Cognome: Batchelor Email: send email Telefono: +44 1256 361785 Fax: +44 1256 361785	UK (Basingstoke)	participant	187˙414.00
7	R.E KAVETSKY INSTITUTE OF EXPERIMENTAL PATHOLOGY ONCOLOGY AND RADIOBIOLOGY OF NATIONAL ACADEMY OF SCIENCES OF UKRAINE  Organization address address: VASYLKIVSKA STR 45 city: KYIV postcode: 3022 contact info Titolo: Prof. Nome: Vladimir Cognome: Nikolaev Email: send email Telefono: 442579055 Fax: 442579055	UA (KYIV)	participant	55˙723.00

Mappa

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 Obiettivo del progetto (Objective)

'The aim of the project is to manufacture an adsorbent carbon based cartridge within a perfusion system for the removal of strongly, protein bound and macromolecular toxins and inflammatory molecules including hepatic and uremic toxins, exotoxin, endotoxin and cytokines. These molecules are responsible for systemic toxicity effects and their removal is negligible or unsustained in current systems available for the treatment of renal, hepatic and multiple organ failure (MOF) related to sepsis. Additionally, removal of these molecules during perfusion of organs for transplant will moderate the inflammatory stress response which currently limits the success of marginal organs. The project considers economical and environmental impact in the development of processing strategies which optimise the adsorptive, biocompatible and hydrodynamic design properties of the resultant system for these applications. The project brings together a multidisciplinary consortium of specialists with many years experience in the development, analysis and clinical implementation of adsorbent biomaterials in extracorporeal systems and in the development of transplant organ preservation techniques.'