MAGNETRODES
Electromagnetic detection of neural activity at cellular resolution
| Coordinatore | COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES
Organization address
address: CEA Saclay - Building 524 - PC 83 contact info |
| Nazionalità Coordinatore | France [FR] |
| Totale costo | 2˙222˙049 € |
| EC contributo | 1˙700˙000 € |
| Programma | FP7-ICT
Specific Programme "Cooperation": Information and communication technologies |
| Code Call | FP7-ICT-2011-9 |
| Funding Scheme | CP |
| Anno di inizio | 2013 |
| Periodo (anno-mese-giorno) | 2013-01-01 - 2015-12-31 |
Partecipanti
| # | ||||
|---|---|---|---|---|
| 1 |
COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES
Organization address
address: CEA Saclay - Building 524 - PC 83 contact info |
FR (Gif-sur-Yvette) | coordinator | 0.00 |
| 2 |
AALTO-KORKEAKOULUSAATIO
Organization address
address: OTAKAARI contact info |
FI (AALTO) | participant | 0.00 |
| 3 |
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
Organization address
address: RUE MICHEL -ANGE contact info |
FR (PARIS) | participant | 0.00 |
| 4 |
ERNST STRUNGMANN INSTITUTE GGMBH
Organization address
address: DEUTSCHORDENSTRASSE contact info |
DE (FRANKFURT AM MAIN) | participant | 0.00 |
| 5 |
INESC MICROSISTEMAS E NANOTECNOLGIAS-INSTITUTO DE ENGENHARIA DE SISTEMAS DE COMPUTADORES PARA OS MICROSISTEMAS E AS NANOTECNOLOGIAS
Organization address
address: Rua Alves Redol contact info |
PT (LISBOA) | participant | 0.00 |
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Obiettivo del progetto (Objective)
The main goal of the project is to develop a new generation of neuroscience tools for electromagnetic measurement and spectroscopy at the neuron level.nSpin electronics offers nowadays the possibility to create very sensitive, micrometer-scale magnetic field detectors. Here, we propose to exploit this technological advance to create novel tools for probing neuronal magnetic fields at the cellular level. The first goal of the project will be to develop the magnetic equivalent of an electrode, a 'magnetrode', sensitive enough to detect the very small magnetic fields induced by the ionic currents flowing within electrically active neurons, and small enough to probe a limited number of cells. We will adapt magnetrodes also for local nuclear magnetic resonance spectroscopy (MRS); thus, they could record both electromagnetic and chemical activity of neurons. In addition, means for local electric or magnetic stimulation could be integrated in to a magnetrode. We will test magnetrodes in vitro and in vivo at various spatial scales, from brain areas down to single neurons. In parallel, based on the measurements with magnetrodes, we will augment existing computational models and develop new ones to characterize the electromagnetic fields emitted by neurons and neuron assemblies. We will use these models to bridge from the activity of single neurons to macroscopic non-invasive measurements such as electroencephalography (EEG) and magnetoencephalography (MEG).nThis project shall pave the way towards 'magnetophysiology', which enables investigating electric activity of neurons without disturbing the ionic flow and without physical contact to the cell. We will create new experimental and modeling tools for magnetic measurements and stimulation at neuron scale. The resulting techniques will be applicable in neurosciences, brain–computer interfacing and possibly in the treatment of certain brain diseases.nThe consortium is composed of 5 teams from 4 EU countries.