METDEF

Metabolic engineering of triterpenoid pathways involved in plant defense in Arabidopsis and rice

 Coordinatore JOHN INNES CENTRE 

 Organization address address: "Norwich Research Park, Colney"
city: NORWICH
postcode: NR4 7UH

contact info
Titolo: Dr.
Nome: Mary
Cognome: Anderson
Email: send email
Telefono: +44 1603 450244
Fax: +44 1603 450045

 Nazionalità Coordinatore United Kingdom [UK]
 Totale costo 221˙606 €
 EC contributo 221˙606 €
 Programma FP7-PEOPLE
Specific programme "People" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013)
 Code Call FP7-PEOPLE-2012-IEF
 Funding Scheme MC-IEF
 Anno di inizio 2013
 Periodo (anno-mese-giorno) 2013-03-04   -   2015-03-03

 Partecipanti

# participant  country  role  EC contrib. [€] 
1    JOHN INNES CENTRE

 Organization address address: "Norwich Research Park, Colney"
city: NORWICH
postcode: NR4 7UH

contact info
Titolo: Dr.
Nome: Mary
Cognome: Anderson
Email: send email
Telefono: +44 1603 450244
Fax: +44 1603 450045

UK (NORWICH) coordinator 221˙606.40

Mappa


 Word cloud

Esplora la "nuvola delle parole (Word Cloud) per avere un'idea di massima del progetto.

genes    triterpenes    species    plant    natural    arabidopsis    rice    et    triterpene    diseases    al    metabolic    pathways    plants    protective    pests    multiple   

 Obiettivo del progetto (Objective)

'Plants produce a diversity array of natural products (otherwise known as secondary metabolites) that have important ecological functions (Dixon 2001; Field and Osbourn 2008). Triterpenes are one of the largest classes of plant-derived natural products. These compounds protect plants against pests and diseases and are also important as drugs and anticancer agents (Papadopoulou et al 1999; Phillips et al 2006; Liby et al 2007). Arabidopsis and also cereals such as rice do not make protective triterpene glycosides (Hostettmann & Marston, 1995; Vincken et al 2007). These model species are therefore excellent experimental systems for proof-of-concept experiments involving metabolic engineering of triterpene pathways into heterologous species. The aim of this proposal is to engineer triterpene metabolic pathways into Arabidopsis and rice by genetic modification. As part of this work I will develop methods for introducing multiple genes into plants using recombineering and synthetic biology approaches. At the end of this project we will have the necessary knowledge to devise strategies to introduce multiple genes into diverse plant species for control of plant pests and diseases based on synthesis of protective triterpenes.'

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