NANOPAD

Nano cellulose based paper diagnostic devices

Coordinatore	KUNGLIGA TEKNISKA HOEGSKOLAN    more  Organization address address: Valhallavaegen 79 city: STOCKHOLM postcode: 10044 contact info Titolo: Mrs. Nome: Maria Cognome: Andersz Email: send email Telefono: 4687908277
Nazionalità Coordinatore	Sweden [SE]
Totale costo	375˙374 €
EC contributo	375˙374 €
Programma	FP7-PEOPLE Specific programme "People" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013)
Code Call	FP7-PEOPLE-2012-IOF
Funding Scheme	MC-IOF
Anno di inizio	2013
Periodo (anno-mese-giorno)	2013-09-01   -   2016-12-31

 Partecipanti

#	participant	country	role	EC contrib. [€]
1	KUNGLIGA TEKNISKA HOEGSKOLAN  Organization address address: Valhallavaegen 79 city: STOCKHOLM postcode: 10044 contact info Titolo: Mrs. Nome: Maria Cognome: Andersz Email: send email Telefono: 4687908277	SE (STOCKHOLM)	coordinator	375˙374.80

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 Obiettivo del progetto (Objective)

'Diagnostic devices made of patterned papers devices, termed microfluidic paper-based analytical devices PADs, are a new platform designed for ASSURED (Affordable, Sensitive, Specific, User-friendly, Rapid and robust, Equipment free and Deliverable to end-users) point-of-care POC diagnostic assays. PADs overcome many disadvantages of strip test devices and offer completely new opportunities to POC.

The design paradigm of PAD is based on creating a complete Lab on a chip, including 2D/3D micro fluidic systems, filtering, biosensing and readout, all combined on a stamp sized piece of paper. The use of conventional paper as a substrate for developing PAD depends on numerous advantages: - The porous structure of paper allows manipulation of fluids through the bulk of the materials, allowing for active fluidics, and filtering. - Paper is thin, lightweight, many dimensions and form factors, easy to stack, store, and transport. - Cellulose is compatible with biological samples, and can be chemically functionalized to bound to proteins, DNA, or small molecules. - Paper is flammable, so PADs can be disposed of by incineration easily and safely after use - Compatibility with printing technologies enables micro fabrication PADs cheap and efficient.

In this project conducting polymer based organic electrochemical transistors will be printed inside PADs and used as a tool for high sensitive diagnostics in PAD.

Nanofibrialted cellulose and nanopaper will be explored for creating new and highly sensitive PAD devices, specially for colorimetric analysis on enzyme markers, and enzyme linked immunosorbent assays (ELISA)

Finally chemically functionalized nanofibrilated cellulose will be explored for covalent attachment of proteins inside nanopaper for high-sensitive and precise paper diagnostics.'