IVSCP

Knowledge Transfer of In vivo surgery and cardiovascular phenotyping for angiogenesis and preeclampsia studies

 Coordinatore ASTON UNIVERSITY 

 Organization address address: ASTON TRIANGLE
city: BIRMINGHAM
postcode: B4 7ET

contact info
Titolo: Prof.
Nome: Asif
Cognome: Ahmed
Email: send email
Telefono: 441212000000

 Nazionalità Coordinatore United Kingdom [UK]
 Totale costo 309˙235 €
 EC contributo 309˙235 €
 Programma FP7-PEOPLE
Specific programme "People" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013)
 Code Call FP7-PEOPLE-2013-IIF
 Funding Scheme MC-IIF
 Anno di inizio 2014
 Periodo (anno-mese-giorno) 2014-05-01   -   2016-04-30

 Partecipanti

# participant  country  role  EC contrib. [€] 
1    ASTON UNIVERSITY

 Organization address address: ASTON TRIANGLE
city: BIRMINGHAM
postcode: B4 7ET

contact info
Titolo: Prof.
Nome: Asif
Cognome: Ahmed
Email: send email
Telefono: 441212000000

UK (BIRMINGHAM) coordinator 309˙235.20

Mappa


 Word cloud

Esplora la "nuvola delle parole (Word Cloud) per avere un'idea di massima del progetto.

host    models    sflt    transfer    redox    vivo    dr    glutaredoxin    aston    university    international    medical    preeclampsia    angiogenesis    angiogenic    murdoch    ivscp    cardiovascular    biology    vascular    regulation    students   

 Obiettivo del progetto (Objective)

'The major aim of this IVSCP project is the knowledge transfer from the Marie Curie International Incoming Fellow (IIF), Dr. Murdoch with strong expertise in cardiovascular microsurgery and background in effectively phenotyping cardiovascular disease in transgenic mouse models to the EU host organisation – Vascular Biology at Aston University. The area of medical research is geared around the knowledge that pivotal in the development of preeclampsia are changes in anti-angiogenic soluble Flt-1 (sFlt-1) and angiogenic placenta growth factor (PlGF). Therefore to find an answer to the current unmet medical need a better understanding of their regulation in preeclampsia and angiogenesis is required. The research aims will drive the knowledge transfer, these include to (i) Assess glutaredoxin-1 as a therapeutic target of preeclampsia; (ii) identify whether Heme oxgenase 1 and cystathionine-g-lyase regulate sFlt-1 by changes in glutaredoxin-1 to effect in vivo angiogenesis; and (iii) Increase our understanding of PIGF gene regulation and function in the endothelium. Dr. Murdoch will aid knowledge transfer through IVSCP by (i) establishing a new research collaboration with his current institute, Vascular Biology Section, Boston University; (ii) provide in vivo training of angiogenesis models and understanding of redox signalling to PhD students and Post-Doctoral Fellows in the host institute and co-host institutes (University of Birmingham and Exeter); (iii) identify novel redox sensitive targets involved in preeclampsia; (iv) provide lectures/practical to undergraduate and MSc students in the School of Life Science; and (v) organise workshops/forums for the wider ERA. Overall, the proposal intends to impart valuable skills and launch an international collaboration. In addition, this will accelerate scientific output from the Vascular Research team which recently moved to Aston University, to maintain its world-leading reputation in preeclampsia.'

Altri progetti dello stesso programma (FP7-PEOPLE)

CONTACT MANIFOLDS (2008)

Complex Projective Contact Manifolds

Read More  

CHIRALMOF (2015)

Rational design of novel nanoprous materials for the separattion of enantiomers

Read More  

EU CRIMINAL SECURITY (2010)

The Criminal Regulatory Network for Private Security Companies: European and International Perspectives

Read More