NeoMark
ICT Enabled Prediction of Cancer Reoccurrence
| Coordinatore | AZIENDA OSPEDALIERO-UNIVERSITARIA DI PARMA
Organization address
address: VIA GRAMSCI 14 contact info |
| Nazionalità Coordinatore | Italy [IT] |
| Totale costo | 3˙981˙536 € |
| EC contributo | 2˙896˙600 € |
| Programma | FP7-ICT
Specific Programme "Cooperation": Information and communication technologies |
| Code Call | FP7-ICT-2007-2 |
| Funding Scheme | CP |
| Anno di inizio | 2008 |
| Periodo (anno-mese-giorno) | 2008-06-01 - 2011-09-30 |
Partecipanti
| # | ||||
|---|---|---|---|---|
| 1 |
AZIENDA OSPEDALIERO-UNIVERSITARIA DI PARMA
Organization address
address: VIA GRAMSCI 14 contact info |
IT (PARMA) | coordinator | 0.00 |
| 2 |
FRAUNHOFER-GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V
Organization address
address: Hansastrasse contact info |
DE (MUENCHEN) | participant | 0.00 |
| 3 |
FUNDACION MD ANDERSON INTERNATIONAL ESPANA
Organization address
address: CALLE GOMEZ HEMANS 2 contact info |
ES (MADRID) | participant | 0.00 |
| 4 |
ISTITUTI FISIOTERAPICI OSPITALIERI
Organization address
address: VIA CHIANESI contact info |
IT (ROMA) | participant | 0.00 |
| 5 |
LINK CONSULTING - TECNOLOGIAS DE INFORMACAO S.A.
Organization address
address: AVENIDA DUQUE D'AVILA 23 contact info |
PT (LISBOA) | participant | 0.00 |
| 6 |
MULTIMED S.R.L.
Organization address
address: VIA PORTINARI DEL PO 21 contact info |
IT (CREMONA) | participant | 0.00 |
| 7 |
PANEPISTIMIO IOANNINON
Organization address
address: LEOFOROS STAVROS S NIARCHOS, PANEPISTIMIOUPOLI IOANNINON contact info |
EL (IOANNINA) | participant | 0.00 |
| 8 |
STMICROELECTRONICS SRL
Organization address
address: VIA C.OLIVETTI contact info |
IT (AGRATE BRIANZA) | participant | 0.00 |
| 9 |
UNIVERSIDAD POLITECNICA DE MADRID
Organization address
address: Calle Ramiro de Maeztu contact info |
ES (MADRID) | participant | 0.00 |
Mappa
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Obiettivo del progetto (Objective)
NeoMark will perform research in the integration of heterogeneous clinical, laboratory, molecular and imaging data to develop a data integration environment facilitating multiscale and multilevel modeling, aimed at advancing models and methods currently in use to predict neoplastic reoccurrences, and to apply it to the study of oral cancer.nSpecifically the scientific target will be to apply this multi-level data integration environment to the monitoring of the disease after remission, in order to early identify local or metastatic reoccurrence of the disease.nThe technical target will be the development of two functional envirnments: one for the definition of biomarker profiles and one for the follow-up of the evolution of the disease. They will be based on the 'fusion' of information from clinical data from health records and standard laboratory markers; from histological data from tumor mass specimens; from high-throughput genomic data from tumor tissue specimens, profiling gene expression at whole-genome level by oligo-RNA microarrays; from high-throughput genomic data from circulating cells specimens (whole blood sample), profiling gene expression at whole-genome level by oligo-RNA microarrays; from imaging data of the prime tumor mass (and secondary localizations if present) through imaging techniques, including image fusion, where relevant.nThe outcomes of the project will be validated in two primary Clinical Centres in Spain and in Italy.nIn this phase the early exploitation of NeoMark will also be assessed through the use of a RT-PCR platform to develop highly individual diagnostic tests to be used both at the time of first diagnosis, as well as for reoccurrence identification.