ITN-LAN

Initial Training Network: Lateralized Attention Networks

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 Obiettivo del progetto (Objective)

'The proposed Initial Training Network for Lateralized Attention Networks (ITN-LAN) brings together 6 research teams with established international reputations and, more importantly, is founded on well established collaborations. The long-term scientific objectives of the proposed ITN-LAN are: (1) To validate and standardize a behavioural battery for assessing the attentional networks of the two cerebral hemispheres and their interaction, (2) To study its neurophysiological correlates using EEG/ERP, fMRI, NIRS and TMS, (3) To assess methods for modulating the attention networks in each hemisphere and their interaction using: (i) biofeedback of the participants own ongoing EEG or fMRI, (ii) TMS to generate selective 'virtual lesions' of hemispheric attentional networks. The focus of the current proposal is to assess critically and rigorously the effectiveness of biofeedback in modulating attention, a goal which has both basic and applied aspects. Common to both aspects is our ability to harness cortical plasticity in the service of ameliorating not only acquired, but also congenital attention deficits. The clinical application has commercial potential and this will be pursued by the industry associated partner (Bio-Keshev). The proposed ITN-LAN offers a comprehensive range of research methods and theories in attention research. First, we cover ALL the non-invasive research methods applied in this field, and second, we look at attention processes at all levels, from sensory to frontal cortex regions, from childhood to old age, and from normal performance to acquired and developmental disorders. We ask to fund 312 person-months, mostly (92%) ESR. One of the centres is located in a less-favoured region. We are privileged to have Prof. Michael Posner as our consultant, being an eminent researcher in the field of attention.'

Introduzione (Teaser)

Thousands of people across the world are affected by attention disorders. New research is developing improved testing methods for attentiveness, which should shed light on brain function in these disorders.

Descrizione progetto (Article)

Congenital and acquired attention deficits are poorly understood in terms of brain function and this hampers treatment. Better tests and analyses are needed, especially when it comes to understanding the attention networks across the two brain hemispheres, or lateralised attention networks (LANs).

The EU-funded 'Initial training network: Lateralised attention networks' (ITN-LAN) project was established to standardise the testing of LAN function. The initiative brought together eight senior research scientists in six research teams, and employed nine new scientists in the field.

Project members specifically sought to develop and standardise related behavioural tests, and to correlate behavioural data with neurophysiological tests of brain function. A further aim was to advance methods of treating attention deficits based on the data generated.

Research efforts have led to the modification of a well established model of attention theory. A series of psychological, physiological and neurological tests were also developed to predict treatment success in stroke recovery.

Brain imaging protocols for learning and attention tasks were developed as well. And, importantly, several interventions were advanced for people suffering from attention problems, including neurofeedback treatment and cognitive training.

At the conclusion of the project, the research team was satisfied that all scientific objectives were met. The investigations were founded on well established collaborations and, from a skills development point of view, helped boost the scientific careers of several young researchers.