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DISCO

Targeted DISCOvery of novel cellulases and hemicellulases and their reaction mechanisms for hydrolysis of lignocellulosic biomass

Coordinatore	TEKNOLOGIAN TUTKIMUSKESKUS VTT Organization address address: TEKNIIKANTIE 4 A city: ESPOO postcode: 02044 VTT contact info Titolo: Ms. Nome: Riitta Cognome: Kervinen Email: send email Telefono: +358 20 722 5206 Fax: +358 20 7227071
Nazionalità Coordinatore	Finland [FI]
Totale costo	4˙001˙460 €
EC contributo	2˙985˙845 €
Programma	FP7-KBBE Specific Programme "Cooperation": Food, Agriculture and Biotechnology
Code Call	FP7-KBBE-2007-1
Funding Scheme	CP-FP
Anno di inizio	2008
Periodo (anno-mese-giorno)	2008-08-01 - 2012-07-31

Partecipanti

#	participant	country	role
1	TEKNOLOGIAN TUTKIMUSKESKUS VTT Organization address address: TEKNIIKANTIE 4 A city: ESPOO postcode: 02044 VTT contact info Titolo: Ms. Nome: Riitta Cognome: Kervinen Email: send email Telefono: +358 20 722 5206 Fax: +358 20 7227071	FI (ESPOO)	coordinator
2	"Institution of the Russian Academy of Sciences, A.N. Bach Institute of Biochemistry of RAS" Organization address address: Leninsky Prospect 33 city: MOSCOW postcode: 119071 contact info Titolo: Prof. Nome: Vladimir Cognome: Popov Email: send email Telefono: +7 495 9523441 Fax: +7 495 9542732	RU (MOSCOW)	participant
3	AGRIFIRM GROUP BV Organization address address: BOOGSCHUTTERSTRAAT 1A city: APELDOORN postcode: 7324 AE contact info Titolo: Mr. Nome: Erik Cognome: Langenhuijzen Email: send email Telefono: 31413382255 Fax: 31413382013	NL (APELDOORN)	participant
4	BIOGOLD OU Organization address address: Lossi city: TALLINN postcode: 12616 contact info Titolo: Mr. Nome: Priit Cognome: Kotli Email: send email Telefono: +372 5013653 Fax: 3726775288	EE (TALLINN)	participant
5	BUDAPESTI MUSZAKI ES GAZDASAGTUDOMANYI EGYETEM Organization address address: MUEGYETEM RAKPART 3 city: BUDAPEST postcode: 1111 contact info Titolo: Prof. Nome: Miklós Cognome: Zrínyi Email: send email Telefono: 3614632277 Fax: 3614632270	HU (BUDAPEST)	participant
6	COOPERATIE CEHAVE LANDBOUWBELANG U.A. Organization address address: POORT VAN VEGHEL 4949 city: VEGHEL postcode: 5466 SB contact info Titolo: Dr. Nome: Albert Jan Cognome: Van Dijk Email: send email Telefono: 31413382255 Fax: 31413382013	NL (VEGHEL)	participant
7	DYADIC NEDERLAND BV Organization address address: NIEUWE KANAAL 7 S city: Wageningen postcode: 6709 PA contact info Titolo: Dr. Nome: Wim Cognome: Van Der Wilden Email: send email Telefono: +31 317 465458 Fax: +31 317 465455	NL (Wageningen)	participant
8	G R WRIGHT AND SONS LTD Organization address address: Ponders End Mills city: ENFIELD postcode: EN3 4Tg contact info Titolo: Ms. Nome: Lesley Cognome: Morris Email: send email Telefono: -2083446856 Fax: -2088040489	UK (ENFIELD)	participant
9	HELSINGIN YLIOPISTO Organization address address: YLIOPISTONKATU 4 city: HELSINGIN YLIOPISTO postcode: 14 contact info Titolo: Dr. Nome: Sanna-Maija Cognome: Miettinen Email: send email Telefono: +358 9 19159792 Fax: +358 9 19158873	FI (HELSINGIN YLIOPISTO)	participant
10	INSTITUTE OF FOOD RESEARCH Organization address address: "Norwich Research Park, Colney" city: NORWICH postcode: NR47UA contact info Titolo: Dr. Nome: Mary Cognome: Anderson Email: send email Telefono: +44 1603 450244 Fax: +44 1603 450887	UK (NORWICH)	participant
11	SEKAB E-TECHNOLOGY AB Organization address address: Hoerneborgsvaegen city: OERNSKOELDSVIK postcode: 89121 contact info Titolo: Dr. Nome: Torbjörn Cognome: Van Der Meulen Email: send email Telefono: +46 660 751 67 Fax: +46 660 549 03	SE (OERNSKOELDSVIK)	participant
12	WAGENINGEN UNIVERSITY Organization address address: DROEVENDAALSESTEEG 4 city: WAGENINGEN postcode: 6708 PB contact info Titolo: Mr. Nome: Jos Cognome: Teunissen Email: send email Telefono: +31 317 485313 Fax: +31 317 484612	NL (WAGENINGEN)	participant

Mappa

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biomass bioethanol enzyme hydrolysis lignocellulosic hemicellulases enzymes co mechanisms

Obiettivo del progetto (Objective)

'The aim of the proposed DISCO project is to develop more efficient and therefore more cost-effective cellulosic and hemicellulosic enzyme tools for the enhanced hydrolysis of pre-treated lignocellulosic biomass in simultaneous saccharification and fermentation (SSF) conditions for bioethanol production. The focus will be on enzymes having increased catalytic activity on various types of relevant European lignocellulosic biomass. In addition enzymes with lower affinity for lignin shall also be developed. Such enzymes would increase the effective amount of cellulases/ hemicellulases for cellulose hydrolysis. Furthermore the recycling of these enzymes would be applicable. The approach in this proposal is to discover the desired activities by combining classical and modern screening technologies. The enzymes will be produced in suitable host systems for industrial enzyme production. The project also focuses on elucidation of enzymatic hydrolysis mechanisms, about which there is a paucity of knowledge. The project will determine the limiting structural factors in these mechanisms by characterisation of the substrate during the course of the hydrolysis and the remaining recalcitrant residue. Synergy between different cellulase and hemicellulases components will also be addresses on the chosen lignocellulosic substrates. Furthermore, the project seeks to demonstrate the proof of concept with the cellulolytic enzymes in a pilot scale using the most relevant European feedstock pretreated wheat straw and related high-volume co-products.'

Introduzione (Teaser)

Bioethanol from plant material is a sustainable alternative to fossil fuels because the carbon dioxide (CO2) emitted is balanced out by the CO2 taken up by the plants as they grow. Scientists investigated production of second generation biofuels from forestry, agriculture and wood-based waste.