PHAGOSYS

"Systems biology of phagosome formation and maturation, modulation by intracellular pathogens"

Coordinatore	IMPERIAL COLLEGE OF SCIENCE, TECHNOLOGY AND MEDICINE    more  Organization address address: SOUTH KENSINGTON CAMPUS EXHIBITION ROAD city: LONDON postcode: SW7 2AZ contact info Titolo: Ms. Nome: Tatjana Cognome: Palalic Email: send email Telefono: +44 20 7594 3866 Fax: +44 20 7594 3868
Nazionalità Coordinatore	United Kingdom [UK]
Totale costo	3˙941˙752 €
EC contributo	2˙990˙375 €
Programma	FP7-HEALTH Specific Programme "Cooperation": Health
Code Call	FP7-HEALTH-2007-B
Funding Scheme	CP-FP
Anno di inizio	2008
Periodo (anno-mese-giorno)	2008-11-01   -   2012-04-30

 Partecipanti

#	participant	country	role	EC contrib. [€]
1	IMPERIAL COLLEGE OF SCIENCE, TECHNOLOGY AND MEDICINE  Organization address address: SOUTH KENSINGTON CAMPUS EXHIBITION ROAD city: LONDON postcode: SW7 2AZ contact info Titolo: Ms. Nome: Tatjana Cognome: Palalic Email: send email Telefono: +44 20 7594 3866 Fax: +44 20 7594 3868	UK (LONDON)	coordinator	0.00
2	ACADEMISCH ZIEKENHUIS LEIDEN  Organization address address: Albinusdreef 2 city: LEIDEN postcode: 2333 ZA contact info Titolo: Ms. Nome: Guillaine Cognome: De Blécourt Email: send email Telefono: +31 71 5263323 Fax: +31 71 5266831	NL (LEIDEN)	participant	0.00
3	INSTITUT JOZEF STEFAN  Organization address address: Jamova 39 city: LJUBLJANA postcode: 1000 contact info Titolo: Mr. Nome: Darko Cognome: Korbar Email: send email Telefono: +386 1 477 3310 Fax: +386 1 251 9385	SI (LJUBLJANA)	participant	0.00
4	MAX PLANCK GESELLSCHAFT ZUR FOERDERUNG DER WISSENSCHAFTEN E.V.  Organization address address: Hofgartenstrasse 8 city: MUENCHEN postcode: 80539 contact info Titolo: Dr. Nome: Birgit Cognome: Knepper-Nicolai Email: send email Telefono: +49 351 2102772 Fax: +49 351 2101089	DE (MUENCHEN)	participant	0.00
5	STICHTING HET NEDERLANDS KANKER INSTITUUT  Organization address address: PLESMANLAAN 121 city: AMSTERDAM postcode: 1066 CX contact info Titolo: Dr. Nome: Henri Cognome: Van Luenen Email: send email Telefono: 31205122097 Fax: 31206991383	NL (AMSTERDAM)	participant	0.00

Mappa

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 Obiettivo del progetto (Objective)

'To address the question of how intracellular pathogens modulate phagosome trafficking in the host cell we propose to use a systems biology approach, using an iterative cycle of experimental data, model, new experimental data, improved model. The ultimate aim of our project is to develop a mathematical model of mycobacteria and Salmonella infection of macrophages that can be applied to find new interventions that promote clearance of intracellular bacteria by phagocytic cells, and so boost innate immunity. To answer this question we have assembled a consortium of European experts able to tackle complementary aspects of this problem. By bringing together these laboratories to focus on a common goal we will be able to lever their expertise far beyond the state of the art.'