ESI-TBVI

"Establishment, Strategy and Initial activities of the TuBerculosis Vaccine Initiative : Coordination of European efforts with global research initiatives."

 Coordinatore "ID-LELYSTAD, INSTITUUT VOOR DIERHOUDERIJ EN DIERGEZONDHEID B.V." 

 Organization address address: Edelhertweg 15
city: LELYSTAD
postcode: 8219PH

contact info
Titolo: Dr.
Nome: Jelle
Cognome: Thole
Email: send email
Telefono: +31 320 2 38508
Fax: -+31 320 2 38050

 Nazionalità Coordinatore Netherlands [NL]
 Totale costo 520˙146 €
 EC contributo 429˙601 €
 Programma FP7-HEALTH
Specific Programme "Cooperation": Health
 Code Call FP7-HEALTH-2007-B
 Funding Scheme CSA-SA
 Anno di inizio 2008
 Periodo (anno-mese-giorno) 2008-05-01   -   2010-04-30

 Partecipanti

# participant  country  role  EC contrib. [€] 
1    "ID-LELYSTAD, INSTITUUT VOOR DIERHOUDERIJ EN DIERGEZONDHEID B.V."

 Organization address address: Edelhertweg 15
city: LELYSTAD
postcode: 8219PH

contact info
Titolo: Dr.
Nome: Jelle
Cognome: Thole
Email: send email
Telefono: +31 320 2 38508
Fax: -+31 320 2 38050

NL (LELYSTAD) coordinator 0.00
2    LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE

 Organization address address: KEPPEL STREET
city: LONDON
postcode: WC1E7HT

contact info
Titolo: Prof.
Nome: Hazel
Cognome: Dockrell
Email: send email
Telefono: 442079000000
Fax: -442079000000

UK (LONDON) participant 0.00
3    MAX PLANCK GESELLSCHAFT ZUR FOERDERUNG DER WISSENSCHAFTEN E.V.

 Organization address address: Hofgartenstrasse 8
city: MUENCHEN
postcode: 80539

contact info
Titolo: Prof.
Nome: Stefan H. E.
Cognome: Kaufmann
Email: send email
Telefono: -28460481
Fax: -28460482

DE (MUENCHEN) participant 0.00
4    STATENS SERUM INSTITUT

 Organization address address: ARTILLERIVEJ 5
city: KOBENHAVN S
postcode: 2300

contact info
Titolo: Prof.
Nome: Peter
Cognome: Andersen
Email: send email
Telefono: 4532683480
Fax: -4532683035

DK (KOBENHAVN S) participant 0.00
5    STICHTING TUBERCULOSIS VACCINE INITIATIVE

 Organization address address: Runderweg 6
city: LELYSTAD
postcode: 8219 PH

contact info
Titolo: Dr.
Nome: Jelle
Cognome: Thole
Email: send email
Telefono: +31 320 2 38508
Fax: +31 320 2 38050

NL (LELYSTAD) participant 0.00

Mappa


 Word cloud

Esplora la "nuvola delle parole (Word Cloud) per avere un'idea di massima del progetto.

tb    clinical    held    steering    expand    completion    ec    teams    public    expertise    vaccine    efforts    board    regular    foundation    governance    tuberculosis    tbvi    private    meetings    trustees    committee    area    office    group    global    related    mobilization    sustain    budget    vaccines    partnership   

 Obiettivo del progetto (Objective)

'The goal is to establish a TB Vaccine Initiative (TBVI) as a private public partnership. It will ensure an appropriate linkage between EC supported projects and global initiatives aiming at the development of new TB vaccines. TBVI will be established as a legal entity stemming from TBVAC, the FP6 EC supported project on TB vaccines, that has proven remarkably successful. TBVI will aim to facilitate the completion of vaccine development by their respective developers, and will not claim the ownership of any new products nor IP rights. Specific objectives of TBVI will be: a-To establish a working group to ensure coordination of activities related to TB vaccine development. It will comprise leaders of AERAS, BMGF, Stop TB (vaccines), TBVI and related EC projects. Regular meetings will be organized to define approaches regarding pre-clinical and clinical development. b- To advocate efforts towards the completion of TB vaccine development, including the mobilization of additional resources. c- To sustain and expand project management activities in the area of TB vaccine development . This will include advisory activities conducted through vaccine-specific product development teams (PDT) and management of specific European projects. The executive operational office will be based in ID-Lelystad (NL). A steering board comprising European scientists, with expertise in vaccine development, will meet on a monthly basis to decide on proposed and ongoing activities, development strategies and selection of new projects. A board of stakeholders/interested parties will review the overall activities and budget, and facilitate the mobilization of resources for TB vaccine development.'

Introduzione (Teaser)

The development of vaccines for tuberculosis is a pressing issue as international migration spreads and disease boundaries fall away.

Descrizione progetto (Article)

The 'Establishment, strategy and initial activities of the tuberculosis vaccine initiative: coordination of European efforts with global research initiatives' (ESI-TBVI) project worked to establish a Tuberculosis Vaccine Initiative (TBVI) as a private public partnership. The goal was to facilitate a productive link between EC-supported projects and worldwide initiatives working to develop new TB vaccines.

A TBVI working group was set up to enhance coordination of activities in the area of TB vaccine development. Regular meetings were held to define preclinical and clinical approaches, assist efforts to complete vaccine development, and sustain and expand relevant project management activities.

The TBVI was established in 2008 as a not-for-profit private foundation. Over 40 TBVI partners belong to 2 programmes for vaccine development: 1 for biomarkers and 1 for support in infrastructure activities and clinical trials development.

Both programmes are managed by a TBVI steering committee, which receives feedback from the product and clinical development teams (guiding the advancement of each product. A board of trustees advises the steering committee on strategic issues and approves the overall TBVI budget, while the governance board verifies process and financial resources of allocated project funds.

Supporting the steering committee, the board of trustees and governance board in their tasks, the operational office prepares project proposals, offers project management expertise and assists in mobilising resources. Activities to mobilise resources resulted in a USD-3-million grant from the Bill & Melinda Gates foundation and approval of the Seventh Framework Programme NEWTBVAC collaborative project proposal.

Meetings were held with various government officials in Belgium, Germany, Spain, France, Hungary, the Netherlands, Finland, Sweden and the UK. In Brussels a public debate was held in the European parliament on 24 March 2010, on the occasion of World Tuberculosis Day.

Annual reports of 2008 and 2009 and the TBVI website provide further information. These wide-ranging activities have created TB awareness and boosted efforts made by TBVI to boost TB vaccine development.

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