NEW ORGANOMETALLICS

Preparation of polyfunctional organometallics: new key intermediates for synthetic organic chemistry

Coordinatore	LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN    more Spiacenti, non ci sono informazioni su questo coordinatore. Contattare Fabio per maggiori infomrazioni, grazie.
Nazionalità Coordinatore	Germany [DE]
Totale costo	2˙061˙000 €
EC contributo	2˙061˙000 €
Programma	FP7-IDEAS-ERC Specific programme: "Ideas" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013)
Code Call	ERC-2008-AdG
Funding Scheme	ERC-AG
Anno di inizio	2008
Periodo (anno-mese-giorno)	2008-12-01   -   2014-11-30

 Partecipanti

#	participant	country	role	EC contrib. [€]
1	LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN  Organization address address: GESCHWISTER SCHOLL PLATZ 1 city: MUENCHEN postcode: 80539 contact info Titolo: Ms. Nome: Monika Cognome: Bernhardt Email: send email Telefono: +49 89 21803449 Fax: +49 89 21802985	DE (MUENCHEN)	hostInstitution	0.00
2	LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN  Organization address address: GESCHWISTER SCHOLL PLATZ 1 city: MUENCHEN postcode: 80539 contact info Titolo: Prof. Nome: Paul Cognome: Knochel Email: send email Telefono: -79901 Fax: -79900	DE (MUENCHEN)	hostInstitution	0.00

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 Obiettivo del progetto (Objective)

The use of organometallic reagents in the last decades completely changed synthetic organic chemistry. These reactive intermediates made now available new materials with outstanding physical properties, novel drugs with excellent activity spectra, modern highly efficient and ecologically benign agrochemicals. The goal of this work is the development of new synthetic routes and a practical access to polyfunctional organometallic reagents using affordable and non-toxic metals such as Mg, Al, Ti, Ca, Mn, and Fe. These new types of organometallics will find an extremely broad range of applications in contemporary organic synthesis. New advanced approaches to these reagents will be based on the recently discovered beneficial influence of environmentally friendly salts such as LiCl on the preparation of these reactive intermediates. Our experience will allow us to design organometallic reagents bearing practically all important functional groups used in organic synthesis. This work will lead to ground-breaking advances in main-group synthetic chemistry and make a broad range of completely novel organometallic compounds available for applications in industry. The availability of such intermediates will revolutionize from the point of view of economy and environmental impact the syntheses of important drugs, modern agrochemicals, as well as perspective compounds with new groundbreaking physical properties for sophisticated electronics and adjacent applications. We plan to study the applications of these new reagents in the field of pharmacology, natural product synthesis, and life and material sciences. The new approach will concentrate on ecologically friendly organometallics of low toxicity and finding the novel synthetic ways in order to minimize the environmental impact of the synthetic intermediates.