MOLMEDREX

MOLecular MEDicine Regional Center of EXcellence

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 Obiettivo del progetto (Objective)

'The Research Centre for Molecular Medicine of the University of Debrecen, is a recognized centre of excellence in molecular medicine. It represents the highest concentration of biomedical research in the Eastern part of Hungary and the only research institute dedicated to carry out research in the field of molecular medicine in the country. However, the competitiveness and potential of the institute, in spite of considerable progress made, is still yet to be implemented. RCMM lacks sufficient amount of expertise in some very dynamically changing areas and would require further investments to upgrade its technical capacity to fully integrate into ERA and to be competitive in obtaining funding. It would also like to work more effectively for the benefit of the local community. MOLMEDREX is focusing on three key areas: genomics, advanced imaging and academic high throughput screening and is aimed at strengthening the S&T potential, improving human resources, upgrading the research equipment, advancing the visibility and impact, increasing success at applying for EU funding. To achieve these the following coherent set of measures will be implemented: twinning and strategic partnerships with institutions in old Member States, including two-way mobility, recruitment of young and experienced researchers, organization of a set of conferences, workshops and practical courses that will contribute to the mobilization of human resources of the RCMM as well as facilitate exchanges with other institutions, targeted dissemination of scientific information and research results of the RCMM toward the local and European scientific community as well as toward the public, including patient groups As a result RCMM will become a more potent and prepared research center in the Eastern part of Hungary with an improved human and infrastructural capacity to tackle key issues in molecular medicine for the benefit of the population of the region.'

Introduzione (Teaser)

The field of molecular medicine has seen revolutionary changes in the past two decades. A research centre at the University of Debrecen in Hungary has upgraded its molecular medicine facility to keep in line with these changes.

Descrizione progetto (Article)

Supporting the upgrading, the project 'Molecular Medicine Regional Center of Excellence' (http://molmedrex.med.unideb.hu/ (MOLMEDREX)) has focused on three key areas: genomics, next-generation sequencing (NGS) and personalised medicine.

A Genomics Centre, set up in 2000, provides genomic services such as sequencing and single nucleotide polymorphism (SNP) analysis. The challenge has been to incorporate genome-wide analyses incorporating epigenetics and NGS for large-scale disease association studies.

The Research Centre for Molecular Medicine (RCMM) responded by making better use of its available clinical resources for serving regional needs to gain international acclaim. The Centre now has 16 research labs, and genomics, imaging and high-throughput screening are the core of molecular medicine in the country. One of its distinguishing features is the high level of integration of its basic research units, core facilities and clinical departments.

To implement the development plan, RCMM has collaborated with two of Europe's foremost molecular biology institutes, the European Molecular Biology Laboratory (EMBL) and Deutsches Krebsforschungszentrum (DKFZ) in Heidelberg, Germany. Partnerships with another 13 European universities have also been forged for knowledge transfer.

To provide critical mass and technical expertise, young scientists have joined the workforce. Four senior and eight junior researchers are now contributing to the scientific visibility of RCMM.In partnership with the twinned institutes, MOLMEDREX has supported the organisation of workshops, conferences and courses. RCMM also serves as a knowledge centre for key groups of the local population such as patient groups, high school students and the media.

Strategic use of state-of-the-art resources is not only providing genomic resources of the highest calibre to the people of Hungary, it is also projecting the work of RCMM into the high-ranking labs of Europe. Ongoing collaboration and knowledge sharing will continue to promote the ranking of RCMM in the world of molecular medicine.