EXCELL

Exploring Cellular Dynamics at Nanoscale

Coordinatore	DANMARKS TEKNISKE UNIVERSITET    more  Organization address address: Anker Engelundsvej 1, Building 101A city: KONGENS LYNGBY postcode: 2800 contact info Titolo: Mr. Nome: Niels Cognome: Freese Email: send email Telefono: +45 45256329 Fax: +45 45887762
Nazionalità Coordinatore	Denmark [DK]
Sito del progetto	http://www.excell.nu
Totale costo	4˙946˙406 €
EC contributo	3˙780˙750 €
Programma	FP7-NMP Specific Programme "Cooperation": Nanosciences, Nanotechnologies, Materials and new Production Technologies
Code Call	FP7-NMP-2007-SMALL-1
Funding Scheme	CP-FP
Anno di inizio	2008
Periodo (anno-mese-giorno)	2008-09-01   -   2011-12-31

 Partecipanti

#	participant	country	role	EC contrib. [€]
1	DANMARKS TEKNISKE UNIVERSITET  Organization address address: Anker Engelundsvej 1, Building 101A city: KONGENS LYNGBY postcode: 2800 contact info Titolo: Mr. Nome: Niels Cognome: Freese Email: send email Telefono: +45 45256329 Fax: +45 45887762	DK (KONGENS LYNGBY)	coordinator	788˙000.00
2	TEL AVIV UNIVERSITY  Organization address address: RAMAT AVIV city: TEL AVIV postcode: 69978 contact info Titolo: Ms. Nome: Lea Cognome: Pais Email: send email Telefono: 972-3-640-8774 Fax: 972-3-640-9697	IL (TEL AVIV)	participant	515˙600.00
3	UNIVERSIDAD AUTONOMA DE MADRID  Organization address address: CALLE EINSTEIN, CIUDAD UNIV CANTOBLANCO RECTORADO 3 city: MADRID postcode: 28049 contact info Titolo: Ms. Nome: Mª Carmen Cognome: Puerta Email: send email Telefono: +34 91 497 8663 Fax: +34 91 497 5503	ES (MADRID)	participant	418˙400.00
4	UNIVERSITA DEGLI STUDI DI GENOVA  Organization address address: VIA BALBI 5 city: GENOVA postcode: 16126 contact info Titolo: Prof. Nome: Daniele Cognome: Caviglia Email: send email Telefono: +39-010-353 6588 Fax: -3532067	IT (GENOVA)	participant	346˙080.00
5	POLITECNICO DI MILANO  Organization address address: PIAZZA LEONARDO DA VINCI 32 city: MILANO postcode: 20133 contact info Titolo: Mr. Nome: Fabio Cognome: Conti Email: send email Telefono: +39 0223993431 Fax: +39 02 23993437	IT (MILANO)	participant	344˙280.00
6	LUXCEL BIOSCIENCES LTD  Organization address address: BIOTRANSFER UNIT SUITE 3-32 BIOL city: CORK contact info Titolo: Dr. Nome: Richard Cognome: Fernandes Email: send email Telefono: -7971458 Fax: 353-1-481-1801	IE (CORK)	participant	329˙010.00
7	UNIVERSITAET POTSDAM  Organization address address: AM NEUEN PALAIS 10 city: POTSDAM postcode: 14469 contact info Titolo: Dr. Nome: Regina Cognome: Gerber Email: send email Telefono: -9771362 Fax: -9771580	DE (POTSDAM)	participant	286˙400.00
8	SCITECH LINK AB  Organization address address: BORGASLINGAN 31 city: LUND postcode: 22472 contact info Titolo: Dr. Nome: Elisabeth Cognome: Csöregi Email: send email Telefono: -128856 Fax: -128856	SE (LUND)	participant	285˙200.00
9	LUNDS UNIVERSITET  Organization address address: Paradisgatan 5c city: LUND postcode: 22100 contact info Titolo: Prof. Nome: Merab Cognome: Kokaia Email: send email Telefono: +46 46 2220547 Fax: +46 46 2220560	SE (LUND)	participant	246˙840.00
10	RESEARCH CENTRE FOR NATURAL SCIENCES, HUNGARIAN ACADEMY OF SCIENCES  Organization address address: PUSZTASZERI UTCA 59-67 city: BUDAPEST postcode: 1025 contact info Titolo: Mr. Nome: Gábor Cognome: Barlai Email: send email Telefono: +36 1 438-1100 ext. 505 Fax: +36 1 438-1164	HU (BUDAPEST)	participant	220˙940.00

Mappa

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 Obiettivo del progetto (Objective)

'EXCELL is a novel innovative approach to explore interaction mechanisms between biological materials and systems/nanostructures. It involves a forward-looking cross-disciplinary and design-based research to generate an integrated, biologically inspired technological platform of high complexity, able to monitor cell dynamics at nano-scale. Expertise in cellular and molecular biology, nanosciences, material engineering, biophysics, biotechnology, modelling, and analytical chemistry, are combined to address the targeted goals, which go beyond the state of the art methods used in traditional biotechnology and systems biology. EXCELL will provide a complete Lab-in-a-Cell (LIC) sensor and actuator platform, which is capable of: (1) studying single cells in their natural environment surrounded by other cells or a complex mixture of different cells/tissue, (2) following the dynamics and interdependence of single cell processes from gene, protein, metabolite to compound secretion, exocytosis and cell-to-cell communication, (3) testing how and where various stimuli affect the different levels of the molecular machinery and finally (4) programming cells to be able to differentiate into a particular phenotype. A major task is the design of suitable biocompatible nano/bio interfaces that ensures a sustainable cellular environment. EXCELL provides a unique opportunity for developing advanced, novel experimental tools to address fundamental problems of stem cell research and poses a potential for possible diversification and modulation of developmental programs of stem cells to differentiate them into specific phenotypes. EXCELL has the capacity to drive new discoveries having a significant impact not only in the field of stem cell research and clinical use, but also on molecular engineering, nanosciences, sensor development, diagnostics, therapeutics, biotechnology and industry (smart materials, medical diagnostics, pharmaceutical companies, start-ups)'