BIOACTIVECPDS
Biologically Active Organic Compounds Interacting with Adenine-binding Proteins
| Coordinatore | Masarykova univerzita
Organization address
address: Zerotinovo namesti 9 contact info |
| Nazionalità Coordinatore | Czech Republic [CZ] |
| Totale costo | 100˙000 € |
| EC contributo | 100˙000 € |
| Programma | FP7-PEOPLE
Specific programme "People" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013) |
| Code Call | FP7-PEOPLE-IRG-2008 |
| Funding Scheme | MC-IRG |
| Anno di inizio | 2010 |
| Periodo (anno-mese-giorno) | 2010-01-01 - 2015-05-01 |
Partecipanti
| # | ||||
|---|---|---|---|---|
| 1 |
Masarykova univerzita
Organization address
address: Zerotinovo namesti 9 contact info |
CZ (BRNO STRED) | coordinator | 100˙000.00 |
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Obiettivo del progetto (Objective)
'Proposed are rational design and synthesis of novel patentable organic compounds that are envisioned to be active against various adenine-binding proteins, e.g. kinases. The structures contain heterocyclic cores relatively unknown in the literature and will mimic interations of purine-containing biological substrates (especially ATP) with proteins that are relevant in oncology. The compounds will be synthesized by modern methods of organic synthesis, namely by ring-closing olefin metathesis and will be profiled in biological assays that include diverse biological targets, especially those that are related to the treatment of cancer.'