NMS Physiome

VPHOP-SIMBIOS cooperation: Tools to develop the NeuroMusculoSkeletal Physiome

Coordinatore	ISTITUTO ORTOPEDICO RIZZOLI    more  Organization address address: VIA DI BARBIANO 1/10 1/10 city: BOLOGNA postcode: 40136 contact info Titolo: Dr. Nome: Andrea Cognome: Rizzi Email: send email Telefono: +39 0516366923 Fax: +39 0516447344
Nazionalità Coordinatore	Italy [IT]
Totale costo	1˙156˙455 €
EC contributo	929˙450 €
Programma	FP7-ICT Specific Programme "Cooperation": Information and communication technologies
Code Call	FP7-ICT-2009-4
Funding Scheme	CP
Anno di inizio	2010
Periodo (anno-mese-giorno)	2010-01-01   -   2013-06-30

 Partecipanti

#	participant	country	role	EC contrib. [€]
1	ISTITUTO ORTOPEDICO RIZZOLI  Organization address address: VIA DI BARBIANO 1/10 1/10 city: BOLOGNA postcode: 40136 contact info Titolo: Dr. Nome: Andrea Cognome: Rizzi Email: send email Telefono: +39 0516366923 Fax: +39 0516447344	IT (BOLOGNA)	coordinator	0.00
2	EMPIRICA GESELLSCHAFT FUER KOMMUNIKATIONS- UND TECHNOLOGIE FORSCHUNG MBH  Organization address address: OXFORDSTRASSE city: BONN postcode: 53111 contact info Titolo: Mr. Nome: Simon Cognome: Robinson Email: send email Telefono: +49 228985300 Fax: +49 2289853012	DE (BONN)	participant	0.00
3	SCS SRL  Organization address address: VIALE FERDINANDO DI SAVOIA 5 city: MILANO postcode: 20124 contact info Titolo: Dr. Nome: Debora Cognome: Testi Email: send email Telefono: +39 051 593543 Fax: +39 051 0544450	IT (MILANO)	participant	0.00
4	THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY  Organization address address: SERRA STREET 651 SUITE 220 city: STANFORD CALIFORNIA postcode: 94305 6203 contact info Titolo: Prof. Nome: Scott Cognome: Delp Email: send email Telefono: +1 6507254009 Fax: +1 6507238544	US (STANFORD CALIFORNIA)	participant	0.00
5	THE UNIVERSITY OF SHEFFIELD  Organization address address: FIRTH COURT WESTERN BANK city: SHEFFIELD postcode: S10 2TN contact info Titolo: Ms. Nome: Joanne Cognome: Watson Email: send email Telefono: +44 114 222 4754 Fax: +44 114 222 1455	UK (SHEFFIELD)	participant	0.00
6	UNIVERSITY OF BEDFORDSHIRE  Organization address address: PARK SQUARE city: LUTON postcode: LU1 3JU contact info Titolo: Prof. Nome: Gordon Cognome: Clapworthy Email: send email Telefono: +44 1582743440 Fax: +44 1582489212	UK (LUTON)	participant	0.00

Mappa

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 Obiettivo del progetto (Objective)

The musculoskeletal apparatus is probably the organ system where the need for the integrative approach advocated by the Virtual Physiological Human (VPH) initiative is most pronounced. The neuromotor control involves the entire body, whereas the processes involved in muscle twitching, bones and muscle adaptation, musculoskeletal aging, and in most musculoskeletal diseases take place at the molecular level. The traditional reductionist approach is reaching dead ends in a number of relevant questions in musculoskeletal research, such as those related to osteoporotic fractures, the pathophysiology of growth in cerebral palsy children, the pathogenesis of rheumatoid arthritis and osteoarthritis, etc. It is becoming more and more evident that the way out is the development of new Information and Communication Technology (ICT) that makes personalised, predictive, and integrative musculoskeletal medicine possible. Worldwide, the two largest research projects focused on this are the Osteoporotic Virtual Physiological Human (VPHOP) integrated project funded by the European Commission, and the Center for Physics-based Simulation of Biological Structures (SIMBIOS) funded by the USA National Institute of Health. Both projects are targeting the same strategic objective, but each project breaks it into research goals that are overlapping in a few cases and complementary in all the others. This unique condition creates an extremely interesting opportunity for international collaboration, which drastically increases the international impact of the work being done by the VPHOP project, and produces the conditions for global cooperation on this grand challenge of biomedical research. With the Neuro Musculo Skeletal Physiome (NMS Physiome) project, the SIMBIOS and VPHOP consortia intend to establish a more organic cooperation, structured around three objectives: integrate the project communities, integrate the projects' tools, and work collaboratively on grand challenges.