NSR-ANP
New Synthetic Reactions for Antitumor Natural Products
| Coordinatore | THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE
Organization address
address: The Old Schools, Trinity Lane contact info |
| Nazionalità Coordinatore | United Kingdom [UK] |
| Totale costo | 250˙229 € |
| EC contributo | 250˙229 € |
| Programma | FP7-PEOPLE
Specific programme "People" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013) |
| Code Call | FP7-PEOPLE-2009-IOF |
| Funding Scheme | MC-IOF |
| Anno di inizio | 2010 |
| Periodo (anno-mese-giorno) | 2010-05-03 - 2013-05-02 |
Partecipanti
| # | ||||
|---|---|---|---|---|
| 1 |
THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE
Organization address
address: The Old Schools, Trinity Lane contact info |
UK (CAMBRIDGE) | coordinator | 250˙229.80 |
Mappa
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Obiettivo del progetto (Objective)
'This project seek to study potential advances in organic synthesis and to apply such advances to the elaboration and study of natural products or natural product congeners of novel biological activity. This project has three main goals of broad relevance. The first is the development of new chemistry, (both in terms of strategy as well as specific reactions) to assist in the synthesis of complex target systems. The second is the application of this chemistry to the synthesis of potentially useful anticancer agents bearing a priviledged and natural-ocurring dipyrrolo[1,2-a:1',2'-d]pyrazine core. Thus, natural products such as phakellins, phakellstatins, palau'amine, spirotryprostatins and structure related to natural products provide the focus for our synthetic efforts. Finally we hope to evaluate, albeit on a qualitative basis some notions as to the mode of action of these substances. It is anticipated that such studies will help to clarify chemical possibilities which might be of relevance to drug activation. This project provides an excellent framework to the transference of chemical efforts to medicinal research in diseases of global impact, such cancer is nowadays.'
Introduzione (Teaser)
The cure for various diseases often exists in nature. Chemistry could provide a helping hand through the development of natural substances with novel biological activity.