MEAD-ET
Novel medical adsorbents for extracorporeal treatment of life threatening conditions
| Coordinatore | UNIVERSITY OF BRIGHTON
Organization address
address: "Lewes Road, Mithras House" contact info |
| Nazionalità Coordinatore | United Kingdom [UK] |
| Totale costo | 113˙400 € |
| EC contributo | 113˙400 € |
| Programma | FP7-PEOPLE
Specific programme "People" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013) |
| Code Call | FP7-PEOPLE-2009-IRSES |
| Funding Scheme | MC-IRSES |
| Anno di inizio | 2010 |
| Periodo (anno-mese-giorno) | 2010-12-01 - 2014-11-30 |
Partecipanti
| # | ||||
|---|---|---|---|---|
| 1 |
UNIVERSITY OF BRIGHTON
Organization address
address: "Lewes Road, Mithras House" contact info |
UK (BRIGHTON) | coordinator | 63˙000.00 |
| 2 |
UNIVERSITE D'AUVERGNE CLERMONT-FERRAND 1
Organization address
address: Boulevard Francois Mitterand 49 contact info |
FR (Clermont-Ferrand) | participant | 50˙400.00 |
Mappa
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Obiettivo del progetto (Objective)
'Recently a program of development of super active carbonic adsorbents for the deep purification of whole blood and blood plasma was realised in the series of joint projects between The EU partners and Ukraine. As a result, nanostructured activated carbons with mass-fractal internal structure and unique capacity towards tightly protein-bound toxins, uncoated or coated with albumin conformers have been synthesized. These materials have been tested and approved for clinical use in Ukraine and Uzbekistan expressly for the treatment of severe hepatic insufficiency, renal insufficiency and multi-organ failure. The goal of this project is the transfer of these findings to a new version of nanostructured carbon, synthesized on the base of phenol-formaldehyde resin modified and coated with haemocompatible dextrans and its sulfated derivates in the Department of Physico-Chemical Mechanisms of Adsorptive Detoxification in the Institute of Experimental Pathology, Oncology and Radiobiology Nat. Acad. of Sci of Ukraine and studied in the School of Pharmacy and Biomolecular Sciences at the University of Brighton (biocompatibility, inflammatory mediator adsorption) and the Laboratory of Immunology, School of Medicine and Pharmacy, University of Clermont-Ferrand (investigation of immunoadsorptive properties of nanostructured carbonic adsorbents coated with sulfated polysaccharides). This program gives the opportunity to cultivate a high scientific quality consortium consisting of 2 European and 1 third country academic institute, with the aim to sustain and create new collaborative partnerships between EU partners and Ukraine, and transfer knowledge and technologies in one of the most exciting fields of modern biomaterial science. Focusing on the development of extracorporeal methods for toxin removal, for the treatment of many life threatening conditions and chronic conditions, that result in a low quality of patient life.'
Introduzione (Teaser)
An EU-funded project is dedicated to the development and characterisation of novel medical adsorbents for blood purification. Potential applications include a number of chronic and acute life threatening conditions.