Explore the words cloud of the PHOCNOSIS project. It provides you a very rough idea of what is the project "PHOCNOSIS" about.
The following table provides information about the project.
Coordinator |
UNIVERSITAT POLITECNICA DE VALENCIA
Organization address contact info |
Coordinator Country | Spain [ES] |
Project website | https://web.archive.org/web/20180412122207/https://phocnosis.eu/ |
Total cost | 4˙146˙163 € |
EC max contribution | 3˙593˙962 € (87%) |
Programme |
1. H2020-EU.3.1.3. (Treating and managing disease) |
Code Call | H2020-PHC-2014-two-stage |
Funding Scheme | RIA |
Starting year | 2015 |
Duration (year-month-day) | from 2015-09-01 to 2019-02-28 |
Take a look of project's partnership.
# | ||||
---|---|---|---|---|
1 | UNIVERSITAT POLITECNICA DE VALENCIA | ES (VALENCIA) | coordinator | 1˙097˙891.00 |
2 | UNIVERSITEIT TWENTE | NL (ENSCHEDE) | participant | 423˙731.00 |
3 | FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V. | DE (MUNCHEN) | participant | 409˙050.00 |
4 | AALBORG UNIVERSITET | DK (AALBORG) | participant | 344˙915.00 |
5 | CDA GMBH | DE (SUHL OT ALBRECHTS) | participant | 336˙537.00 |
6 | ST GEORGE'S HOSPITAL MEDICAL SCHOOL | UK (LONDON) | participant | 315˙937.00 |
7 | EV GROUP E. THALLNER GMBH | AT (ST FLORIAN AM INN) | participant | 257˙650.00 |
8 | BIONOS BIOTECH SL | ES (VALENCIA) | participant | 227˙000.00 |
9 | DB VENTURE BUILDER SL | ES (VALENCIA) | participant | 131˙515.00 |
10 | GENERA BIOTECH SL | ES (PATERNA VALENCIA) | participant | 49˙734.00 |
11 | ART OF TECHNOLOGY AG | CH (ZURICH) | participant | 0.00 |
The PHOCNOSIS project aims at the development and the preclinical validation of a nanotechnology-based handheld point-of-care testing (POCT) analysis device for its application in the early diagnosis of cardiovascular diseases (CVD). The diagnosis will be carried out by means of the fast (<10 minutes), ultra-sensitive (<1 ng/L) and label-free detection of multiple cardiac biomarkers, using a small volume of whole blood (<100 μL). This POCT analysis device will significantly help in the implementation of mass screening programs, with the consequent impact on clinical management, reducing also costs of treatments, and increasing survival rates. The PHOCNOSIS analysis device will be based on two state-of-the-art technological elements in order to obtain a compact and highly sensitive final device. First, an integrated micro-/nanofluidic system will be used for biomarkers separation, purification and concentration, targeting an effective concentration increase by a factor greater than 1000x for the targeted biomarkers. Then, the concentrated biomarkers will be detected using a novel nanophotonic-based sensing technique, envisaging a final combined detection limit below 1 ng/L. This novel sensing technique allows us to obtain systems which are low-cost, compact and with a lower complexity, thus making them suitable for the development of portable devices for POCT. The PHOCNOSIS project will target the deployment of disposable biochips with an envisaged cost below €3 to be used in a handheld analysis device with an envisaged cost below €3000. Special attention will be paid within the PHOCNOSIS project to explore the potential deployment and commercialisation of the analysis device, by means of the involvement of relevant academic and industrial partners, as well as end users.
year | authors and title | journal | last update |
---|---|---|---|
2019 |
L. Torrijos-Morán, J. GarcÃa-Rupérez Single-channel bimodal interferometric sensor using subwavelength structures published pages: 8168, ISSN: 1094-4087, DOI: 10.1364/oe.27.008168 |
Optics Express 27/6 | 2019-09-09 |
2017 |
Odete Gonçalves, Scott Snider, Ruben Zadoyan, Quoc-Thang Nguyen, Henrik Vorum, Steffen B. Petersen, Maria Teresa Neves-Petersen Novel microfabrication stage allowing for one-photon and multi-photon light assisted molecular immobilization and for multi-photon microscope published pages: 100790F, ISSN: , DOI: 10.1117/12.2250567 |
Reporters, Markers, Dyes, Nanoparticles, and Molecular Probes for Biomedical Applications IX | 2019-09-09 |
2018 |
V.A. Papadimitriou, L.I. Segerink, A. van den Berg, J.C.T. Eijkel 3D capillary stop valves for versatile patterning inside microfluidic chips published pages: 232-238, ISSN: 0003-2670, DOI: 10.1016/j.aca.2017.11.055 |
Analytica Chimica Acta 1000 | 2019-09-09 |
2019 |
Jad Sabek, Paula MartÃnez-Pérez, Jaime GarcÃa-Rupérez Computational binding study of cardiac troponin I antibody towards cardiac versus skeletal troponin I published pages: 147-151, ISSN: 1476-9271, DOI: 10.1016/j.compbiolchem.2019.04.002 |
Computational Biology and Chemistry 80 | 2019-09-09 |
2019 |
Jad Sabek, Luis Torrijos-Morán, Amadeu Griol, Zeneida DÃaz Betancor, MarÃa-José Bañuls Polo, Ãngel Maquieira, Jaime GarcÃa-Rupérez Real Time Monitoring of a UV Light-Assisted Biofunctionalization Protocol Using a Nanophotonic Biosensor published pages: 6, ISSN: 2079-6374, DOI: 10.3390/bios9010006 |
Biosensors 9/1 | 2019-09-09 |
2018 |
Rafael Alonso, Pilar Jiménez-Meneses, Jaime GarcÃa-Rupérez, MarÃa-José Bañuls, Ãngel Maquieira Thiol–ene click chemistry towards easy microarraying of half-antibodies published pages: 6144-6147, ISSN: 1359-7345, DOI: 10.1039/c8cc01369a |
Chemical Communications 54/48 | 2019-09-09 |
2019 |
MarÃa-José Bañuls, Miguel Ãngel González-MartÃnez, Jad Sabek, Jaime GarcÃa-Rupérez, Ãngel Maquieira Thiol-click photochemistry for surface functionalization applied to optical biosensing published pages: 103-113, ISSN: 0003-2670, DOI: 10.1016/j.aca.2019.01.055 |
Analytica Chimica Acta 1060 | 2019-09-09 |
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The information about "PHOCNOSIS" are provided by the European Opendata Portal: CORDIS opendata.