MeTABLE
Advanced bioinformatics for genome and metagenome analyses and discovery of novel biocatalists from extremophiles: implications for improving industrial bioprocesses
Total Cost €
0EC-Contrib. €
0Partnership
0Views
0MeTABLE project word cloud
Explore the words cloud of the MeTABLE project. It provides you a very rough idea of what is the project "MeTABLE" about.
Project "MeTABLE" data sheet
The following table provides information about the project.
| Coordinator |
UNIVERSITA DEGLI STUDI DI CAMERINO
Organization address contact info |
| Coordinator Country | Italy [IT] |
| Project website | http://www.metable.eu/metable/ |
| Total cost | 337˙500 € |
| EC max contribution | 337˙500 € (100%) |
| Programme |
1. H2020-EU.1.3.3. (Stimulating innovation by means of cross-fertilisation of knowledge) |
| Code Call | H2020-MSCA-RISE-2014 |
| Funding Scheme | MSCA-RISE |
| Starting year | 2014 |
| Duration (year-month-day) | from 2014-12-01 to 2018-11-30 |
Partnership
Take a look of project's partnership.
| # | ||||
|---|---|---|---|---|
| 1 | UNIVERSITA DEGLI STUDI DI CAMERINO | IT (CAMERINO) | coordinator | 81˙000.00 |
| 2 | EPIGENETIKS GENETIK BIYOINFORMATIK YAZILIM AS | TR (ISTANBUL) | participant | 130˙500.00 |
| 3 | UNIVERSITA' DEGLI STUDI DI MILANO-BICOCCA | IT (MILANO) | participant | 58˙500.00 |
| 4 | BIOMOLECULAR RESEARCH GENOMICS SRL | IT (PADOVA) | participant | 45˙000.00 |
| 5 | THE CHANCELLOR MASTERS AND SCHOLARSOF THE UNIVERSITY OF CAMBRIDGE | UK (CAMBRIDGE) | participant | 22˙500.00 |
| 6 | ELVESYS | FR (PARIS) | participant | 0.00 |
| 7 | COMSATS INSTITUTE OF INFORMATION TECHNOLOGY | PK (Islamabad) | partner | 0.00 |
Map
Project objective
The aim of this proposal is to acquire new insights about the mechanisms of environmental adaptation, particularly for cold-adapted organisms, and to discover novel metabolic pathways and enzymes with potential industrial value. We intend to accomplish this goal by establishing a collaboration and a knowledge-exchange network between industrial and academic partners aiming at developing bioinformatic tools for genomic analysis and biotechnology tools for directed evolution. The partners present high complementarity: UNICAM holds genomic sequences from psychrophilic and mesophilic ciliates that need to be annotated and analysed. Sabanci provides environmental samples for the isolation and characterization of new extremophiles. CAMBRIDGE provides the know-how for the discovery of new metabolic pathways valuable for understanding environmental adaptation. BMR Genomics and COMSATS possess all the facilities for genome sequencing and annotation and bioinformatic expertise with the purpose of developing new tools to analyse genomes of microorganisms from extreme environment. UNIMIB owns the facilities for the heterologous expression of gene sequences in bacteria and yeasts and technologies to assess and implement the properties of novel enzymes towards industrial application. We are confident that the establishment of the international research network proposed, with its synergistic effects, will significantly contribute to push all the involved laboratories to the top level in the field of production of active biomolecules and in the discovery of mechanisms of molecular adaptation under extreme environmental conditions. These discoveries may help the manufacturing of a new generation of ordinary facilities, as cleaning agents, biofuels, with a significant impact on the everyday life of European citizens.
Deliverables
| Optimized biomolecules | Other | 2019-08-06 18:17:09 |
| Patents | Websites, patent fillings, videos etc. | 2019-08-06 18:17:09 |
| optimized molecules for bioremediation | Other | 2019-08-06 18:17:09 |
| patent on optimized biomolecules | Websites, patent fillings, videos etc. | 2019-08-06 18:17:09 |
| Characterized new biocatalists | Other | 2019-08-06 18:17:08 |
| genome annotations | Other | 2019-08-06 18:17:07 |
| E. focardii genome database and identification of sequences encoding molecules of interest for industrial applications. | Documents, reports | 2019-08-06 18:17:08 |
| proposals for new projects | Documents, reports | 2019-08-06 18:17:08 |
| Web page ,Twitter and Facebook account | Documents, reports | 2019-08-06 18:17:07 |
| reports on new biocatalists | Documents, reports | 2019-08-06 18:17:06 |
| Isolation of microbes that can survive to extreme environments for cultivation when possible that can survive to extreme environments for cultivation when possibles | Other | 2019-08-06 18:17:07 |
| characterization of biocatalysts of interest | Other | 2019-08-06 18:17:07 |
| Characterized new metabolic pathways | Other | 2019-08-06 18:17:08 |
| Improved bioinformatics tools | Documents, reports | 2019-08-06 18:17:07 |
| Joint publications concerning WP1-WP5 | Documents, reports | 2019-08-06 18:17:08 |
| New insight on the molecular mechanisms responsible for cold-adaptation and/or environmental adaptation | Documents, reports | 2019-08-06 18:17:07 |
| metagenome sequence and annotation | Documents, reports | 2019-08-06 18:17:07 |
| New rules for system biology | Documents, reports | 2019-08-06 18:17:07 |
| patenting and industrial applications | Documents, reports | 2019-08-06 18:17:07 |
| trained researchers on bioinformatics | Other | 2019-08-06 18:17:07 |
Take a look to the deliverables list in detail: detailed list of MeTABLE deliverables.
Publications
| year | authors and title | journal | last update |
|---|---|---|---|
| 2018 |
Alessio Mancini, Sandra Pucciarelli Antibiotic activity of the antioxidant drink effective Microorganism-X (EM-X) extracts against common nosocomial pathogens: an in vitro study published pages: 1-6, ISSN: 1478-6419, DOI: 10.1080/14786419.2018.1517344 |
Natural Product Research | 2019-10-08 |
| 2018 |
Alessio Mancini, Filmon Eyassu, Maxwell Conway, Annalisa Occhipinti, Pietro Liò, Claudio Angione, Sandra Pucciarelli CiliateGEM: an open-project and a tool for predictions of ciliate metabolic variations and experimental condition design published pages: 1-11, ISSN: 1471-2105, DOI: 10.1186/s12859-018-2422-9 |
BMC Bioinformatics 19/S15 | 2019-08-06 |
| 2018 |
Alessandro Pischedda, Kesava Priyan Ramasamy, Marco Mangiagalli, Federica Chiappori, Luciano Milanesi, Cristina Miceli, Sandra Pucciarelli, Marina Lotti Antarctic marine ciliates under stress: superoxide dismutases from the psychrophilic Euplotes focardii are cold-active yet heat tolerant enzymes published pages: , ISSN: 2045-2322, DOI: 10.1038/s41598-018-33127-1 |
Scientific Reports 8/1 | 2019-08-06 |
| 2018 |
Aleksei Kaleda, Lotem Haleva, Guy Sarusi, Tova Pinsky, Marco Mangiagalli, Maya Bar Dolev, Marina Lotti, Marco Nardini, Ido Braslavsky Saturn-Shaped Ice Burst Pattern and Fast Basal Binding of an Ice-Binding Protein from an Antarctic Bacterial Consortium published pages: , ISSN: 0743-7463, DOI: 10.1021/acs.langmuir.8b01914 |
Langmuir | 2019-08-06 |
| 2019 |
Tyler D.R. Vance, Maddalena Bayer-Giraldi, Peter L. Davies, Marco Mangiagalli Ice-binding proteins and the ‘domain of unknown function’ 3494 family published pages: , ISSN: 1742-464X, DOI: 10.1111/febs.14764 |
The FEBS Journal | 2019-08-06 |
| 2018 |
M. Lotti, S. Brocca, M. Mangiagalli, A. Pischedda, M. Orlando, S. Maione, D. De Pascale, S. Pucciarelli, M. Nardini, I. Braslavsky Enzymes and ice binding proteins from Antarctic organisms published pages: S43-S44, ISSN: 1871-6784, DOI: 10.1016/j.nbt.2018.05.091 |
New Biotechnology 44 | 2019-08-06 |
| 2017 |
Katre Juganson, Monika Mortimer, Angela Ivask, Sandra Pucciarelli, Cristina Miceli, Kaja Orupõld, Anne Kahru Mechanisms of toxic action of silver nanoparticles in the protozoan Tetrahymena thermophila : From gene expression to phenotypic events published pages: , ISSN: 0269-7491, DOI: 10.1016/j.envpol.2017.03.013 |
Environmental Pollution | 2019-08-06 |
| 2018 |
Marco Mangiagalli, Guy Sarusi, Aleksei Kaleda, Maya Bar Dolev, Valentina Nardone, Vittoria Federica Vena, Ido Braslavsky, Marina Lotti, Marco Nardini Structure of a bacterial ice binding protein with two faces of interaction with ice published pages: 1653-1666, ISSN: 1742-464X, DOI: 10.1111/febs.14434 |
The FEBS Journal 285/9 | 2019-08-06 |
| 2017 |
Guang Yang, Hua Yao, Matteo Mozzicafreddo, Patrizia Ballarini, Sandra Pucciarelli, Cristina Miceli Rational engineering of a cold-adapted α-amylase from the Antarctic ciliate Euplotes focardii for simultaneous improvement of thermostability and catalytic activity published pages: AEM.00449-17, ISSN: 0099-2240, DOI: 10.1128/AEM.00449-17 |
Applied and Environmental Microbiology | 2019-08-06 |
Are you the coordinator (or a participant) of this project? Plaese send me more information about the "METABLE" project.
For instance: the website url (it has not provided by EU-opendata yet), the logo, a more detailed description of the project (in plain text as a rtf file or a word file), some pictures (as picture files, not embedded into any word file), twitter account, linkedin page, etc.
Send me an email (fabio@fabiodisconzi.com) and I put them in your project's page as son as possible.
Thanks. And then put a link of this page into your project's website.
The information about "METABLE" are provided by the European Opendata Portal: CORDIS opendata.
More projects from the same programme (H2020-EU.1.3.3.)
ROVER (2020)
RELIABLE TECHNOLOGIES AND MODELS FOR VERIFIED WIRELESS BODY-CENTRIC TRANSMISSION AND LOCALIZATION
Read MoreMAIL (2019)
Identifying Marginal Lands in Europe and strengthening their contribution potentialities in a CO2sequestration strategy
Read MoreOPEN (2019)
Outcomes of Patients’ Evidence With Novel, Do-It-Yourself Artificial Pancreas Technology
Read More