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YAKUT SIGNED

Genomics, epigenomics and transcriptomics of Yakutian horses, a unique domestic breed adapted to life in the Arctic

Total Cost €

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EC-Contrib. €

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Partnership

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 YAKUT project word cloud

Explore the words cloud of the YAKUT project. It provides you a very rough idea of what is the project "YAKUT" about.

horses    succeeded    reconstruct    deep    mechanisms    spectacular    sound    transcriptomics    winter    russian    country    yakutia    strategies    extreme    hair    breed    70    record    dna    levels    yakut    ordm    time    controversial    expression    dataset    modifications    people    capacities    extensive    ancient    exceptional    genomic    care    republic    vegetation    receive    temperatures    arctic    hemisphere    cattle    origin    epigenetic    air    domestic    life    responsible    cold    underlying    first    genetic    amazing    epigenomics    parked    sakha    breeding    evolutionary    economy    northern    tools    human    efforts    reveal    snow    cutting    preserve    contrast    stables    origins    living    densities    regulating    cover    months    coldest    edge    heritage    yakutian    history    environment    unsurprisingly    metabolic    mysterious    metabolism    despite    gene    federation    found    natural    seasonal    adaptations    horse    grazing    genomics    genome   

Project "YAKUT" data sheet

The following table provides information about the project.

Coordinator		 KOBENHAVNS UNIVERSITET 

Organization address
address: NORREGADE 10
city: KOBENHAVN
postcode: 1165
website: www.ku.dk

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.
 Coordinator Country Denmark [DK]
 Total cost 200˙194 €
 EC max contribution 200˙194 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2014
 Funding Scheme MSCA-IF-EF-ST
 Starting year 2015
 Duration (year-month-day) from 2015-09-15   to  2017-09-14

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    KOBENHAVNS UNIVERSITET DK (KOBENHAVN) coordinator 200˙194.00

Map

 Project objective

Yakutia (Sakha Republic, Russian Federation) is the coldest country in the Northern hemisphere with winter record temperatures as low as -70ºC. Despite such extreme conditions, the Yakut people succeeded in developing an economy based on extensive horse and cattle breeding. In contrast to cattle, that are parked in stables at winter, horses do not receive much human care, living all the year in the open air and grazing on vegetation that is under deep snow cover for 7-8 months. Unsurprisingly, Yakutian horses developed amazing adaptations to life in the cold Arctic, including exceptional hair densities for domestic horses and spectacular capacities for regulating their metabolism. The origin of Yakutian horses is controversial. In the YAKUT project, we will use cutting-edge genomic tools including genomics, transcriptomics and epigenomics, together with state-of-the-art methods in ancient DNA research, to reconstruct the evolutionary history of Yakutian horses from its mysterious origins to its adaptation to life in the Arctic. Our extensive genomic dataset will provide essential information to foster efforts for developing sound management strategies to preserve this unique genetic heritage. Following seasonal gene expression levels and associated epigenetic modifications at the whole genome scale, we will reveal for the first time the mechanisms responsible for the exceptional metabolic adaptations found in Yakutian horses. Overall, the YAKUT project aims at understanding the process of natural selection underlying the adaptation of a domestic breed to life in an extreme environment.

 Publications

year authors and title journal last update
List of publications.
2016 Michela Leonardi, Pablo Librado, Clio Der Sarkissian, Mikkel Schubert, Ahmed H. Alfarhan, Saleh A. Alquraishi, Khaled A. S. Al-Rasheid, Cristina Gamba, Eske Willerslev, Ludovic Orlando
Evolutionary Patterns and Processes: Lessons from Ancient DNA
published pages: syw059, ISSN: 1063-5157, DOI: 10.1093/sysbio/syw059 		Systematic Biology 2019-06-13
2016 P. Librado, A. Fages, C. Gaunitz, M. Leonardi, S. Wagner, N. Khan, K. Hanghoj, S. A. Alquraishi, A. H. Alfarhan, K. A. Al-Rasheid, C. Der Sarkissian, M. Schubert, L. Orlando
The Evolutionary Origin and Genetic Makeup of Domestic Horses
published pages: 423-434, ISSN: 0016-6731, DOI: 10.1534/genetics.116.194860 		Genetics 204/2 2019-06-13

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