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platinDx

A test for predicting the efficacy of common platinum drugs enabling personalized chemotherapy for bladder cancer patients.

Total Cost €

EC-Contrib. €

Partnership

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Outcomes and
results

platinDx project word cloud

Explore the words cloud of the platinDx project. It provides you a very rough idea of what is the project "platinDx" about.

diagnostics market rapid appropriate certification alternative quantitation 4bn primary accelerator lung gain unnecessary measured innovation dose service tissue white benefit 75 tissye launch platindx clinical 60 diagnoistics tumor predictor personalise trial ams levels appropriately treatments adress medical microdose bladder damage wasted chemotherapy annually drug mass assay biopsy accelerated intend 1 patients dna cancer distinguish blood spectrometry accurate 500 therapeutic run platinum scaled followed cured intervention adducts cells

Project "platinDx" data sheet

The following table provides information about the project.

Coordinator	ACCELERATED MEDICAL DIAGNOSTICS LTD Organization address address: 72 Great Suffolk Street city: London postcode: SE1 0BL website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.
Coordinator Country	United Kingdom [UK]
Project website	http://accleratedmeddiagnostics.com
Total cost	71˙429 €
EC max contribution	50˙000 € (70%)
Programme	1. H2020-EU.3.1.3. (Treating and managing disease)
Code Call	H2020-SMEINST-1-2014
Funding Scheme	SME-1
Starting year	2015
Duration (year-month-day)	from 2015-05-01 to 2015-10-31

Partnership

Take a look of project's partnership.

#	participants	country	role	EC contrib. [€]
1	ACCELERATED MEDICAL DIAGNOSTICS LTD ACCELERATED MEDICAL DIAGNOSTICS LTD Organization address address: 72 Great Suffolk Street city: London postcode: SE1 0BL website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	UK (London)	coordinator	50˙000.00
2	HAMMERSMITH MEDICINES RESEARCH LTD HAMMERSMITH MEDICINES RESEARCH LTD Organization address address: 44 CUMBERLAND AVENUE city: LONDON postcode: NW10 7EW website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	UK (LONDON)	participant	0.00

Map

Project objective

Platinum-based chemotherapy is the primary therapeutic intervention for over 500,000 patients per year in the EU. Although some patients are cured by this type of chemotherapy, as many as 75% of lung cancer patients and 60% of bladder cancer patients show no benefit and could be more appropriately given alternative treatments, and therefore over €4bn annually is wasted on unnecessary treatments. There is a need for a rapid, accurate test to distinguish those patients who are likely to respond to chemotherapy and those who are not. Accelerated Medical Diagnostics aim to personalise chemotherapy for cancer patients through their own developed PlatinDx assay, which can be used to identify those patients which are appropriate for platinum-based chemotherapy. Cancer patients are given a microdose (1% of the therapeutic dose) of a platinum-based drug, followed by quantitation of drug-DNA adducts in biopsy tissye using accelerator mass spectrometry (AMS). Levels of drug-DNA damage are measured by AMS in white blood cells and tumor biopsy tissue, which are used as a predictor of therapeutic response. Within the innovation project Accelerated Medical Diagnoistics intend to: gain medical certification within the EU; run a scaled up clinical trial to gain significant results; and adress the EU market and launch their service in the EU.

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The information about "PLATINDX" are provided by the European Opendata Portal: CORDIS opendata.