ENCOMOLE-2i SIGNED
Endoscopic Comprehensive Optical Multimodal Molecular Intelligent Imaging
Total Cost €
0EC-Contrib. €
0Partnership
0Views
0ENCOMOLE-2i project word cloud
Explore the words cloud of the ENCOMOLE-2i project. It provides you a very rough idea of what is the project "ENCOMOLE-2i" about.
Project "ENCOMOLE-2i" data sheet
The following table provides information about the project.
| Coordinator |
UNIVERSITAET zu LUEBECK
Organization address contact info |
| Coordinator Country | Germany [DE] |
| Total cost | 1˙998˙530 € |
| EC max contribution | 1˙998˙530 € (100%) |
| Programme |
1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC)) |
| Code Call | ERC-2014-CoG |
| Funding Scheme | ERC-COG |
| Starting year | 2016 |
| Duration (year-month-day) | from 2016-01-01 to 2020-12-31 |
Partnership
Take a look of project's partnership.
| # | ||||
|---|---|---|---|---|
| 1 | UNIVERSITAET zu LUEBECK | DE (LUBECK) | coordinator | 1˙998˙530.00 |
Map
Project objective
Optical imaging has exceptional potential for medical diagnosis, because it can provide high spatial resolution and molecular contrast. However, for in vivo imaging in humans, the poor penetration of only a few millimetres is a major obstacle. Optical endoscopes solve this problem, but currently most of them only perform non-advanced, classical white light imaging. Also, the speed of current devices is not sufficient to comprehensively scan entire organs at microscopic resolution. Hence, medical imaging is still dominated by non-optical techniques like X-ray, ultrasound and magnetic resonance imaging. The objective of ENCOMOLE-2i is to push the performance of advanced optical in vivo imaging techniques to cross the application threshold for clinical research and practice. An endoscopic multi-modal molecular imaging platform will be developed with unprecedented capabilities for the diagnosis of disease. The hardware technology development includes three novel imaging modalities. Optical coherence tomography with line rates of several Megahertz will be used for comprehensive structural imaging over large areas. Time encoded stimulated Raman sensing, supported by a new type of two photon microscopy, will be used for guided and referenced molecular imaging. Combining these techniques into one system and interfacing it with a newly developed endoscope will generate great synergy. Moreover, the unique synchronization capabilities of these modalities enable a radically new strategy for more efficient data acquisition: The concept of adaptive “Intelligent Imaging”. The goal is to develop a universal endoscopy platform which can then be specifically tailored to the individual application. In the project the focus is on gastrointestinal imaging. The synergy between technological and algorithmic advances in ENCOMOLE-2i will break ground for more optical in vivo imaging in clinical research and routine, which can finally lead to improved diagnosis of many types of disease.
Publications
| year | authors and title | journal | last update |
|---|---|---|---|
| 2017 |
Tianshi Wang, Tom Pfeiffer, Min Wu, Wolfgang Wieser, Gaetano Amenta, Wolfgang Draxinger, Antonius F. W. van der Steen, Robert Huber, Gijs van Soest Thermo-elastic optical coherence tomography published pages: 3466, ISSN: 0146-9592, DOI: 10.1364/ol.42.003466 |
Optics Letters 42/17 | 2020-02-21 |
| 2017 |
Matthias Eibl, Sebastian Karpf, Hubertus Hakert, Daniel Weng, Robert Huber Two-photon-excited fluorescence (TPEF) and fluorescence lifetime imaging (FLIM) with sub-nanosecond pulses and a high analog bandwidth signal detection published pages: 100691F, ISSN: , DOI: 10.1117/12.2250831 |
Multiphoton Microscopy in the Biomedical Sciences XVII | 2020-02-21 |
| 2017 |
Christian Jirauschek, Robert Huber Efficient simulation of the swept-waveform polarization dynamics in fiber spools and Fourier domain mode-locked (FDML) lasers published pages: 1135, ISSN: 0740-3224, DOI: 10.1364/JOSAB.34.001135 |
Journal of the Optical Society of America B 34/6 | 2020-02-21 |
| 2016 |
Sebastian Karpf, Matthias Eibl, Benjamin Sauer, Fred Reinholz, Gereon Hüttmann, Robert Huber Two-photon microscopy using fiber-based nanosecond excitation published pages: 2432, ISSN: 2156-7085, DOI: 10.1364/BOE.7.002432 |
Biomedical Optics Express 7/7 | 2020-02-21 |
| 2018 |
Hinnerk Schulz-Hildebrandt, Tom Pfeiffer, Tim Eixmann, Sabrina Lohmann, Martin Ahrens, Joshua Rehra, Wolfgang Draxinger, Peter König, Robert Huber, Gereon Hüttmann High-speed fiber scanning endoscope for volumetric multi-megahertz optical coherence tomography published pages: 4386, ISSN: 0146-9592, DOI: 10.1364/ol.43.004386 |
Optics Letters 43/18 | 2020-02-21 |
| 2016 |
Tom Pfeiffer, Wolfgang Wieser, Thomas Klein, Markus Petermann, Jan-Phillip Kolb, Matthias Eibl, Robert Huber Flexible A-scan rate MHz OCT: computational downscaling by coherent averaging published pages: 96970S, ISSN: , DOI: 10.1117/12.2214788 |
Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XX | 2020-02-21 |
| 2017 |
Cuiping Yao, Florian Rudnitzki, Gereon Hüttmann, Zhenxi Zhang, Ramtin Rahmanzadeh Important factors for cell-membrane permeabilization by gold nanoparticles activated by nanosecond-laser irradiation published pages: 5659-5672, ISSN: 1178-2013, DOI: 10.2147/IJN.S140620 |
International Journal of Nanomedicine Volume 12 | 2020-02-21 |
| 2017 |
Thomas Klein, Robert Huber High-speed OCT light sources and systems [Invited] published pages: 828, ISSN: 2156-7085, DOI: 10.1364/BOE.8.000828 |
Biomedical Optics Express 8/2 | 2020-02-21 |
| 2017 |
Tianshi Wang, Tom Pfeiffer, Min Wu, Wolfgang Wieser, Wolfgang Draxinger, Antonius F. W. van der Steen, Robert Huber, Gijs van Soest Short pulse laser induced thermo-elastic deformation imaging published pages: 100620C, ISSN: , DOI: 10.1117/12.2251502 |
Optical Interactions with Tissue and Cells XXVIII | 2020-02-21 |
| 2017 |
Matthias Eibl, Sebastian Karpf, Daniel Weng, Hubertus Hakert, Tom Pfeiffer, Jan Philip Kolb, Robert Huber Single pulse two photon fluorescence lifetime imaging (SP-FLIM) with MHz pixel rate published pages: 3132, ISSN: 2156-7085, DOI: 10.1364/BOE.8.003132 |
Biomedical Optics Express 8/7 | 2020-02-21 |
| 2017 |
Sebastian Karpf, Matthias Eibl, Wolfgang Wieser, Thomas Klein, Robert Huber Shot-Noise Limited Time-Encoded Raman Spectroscopy published pages: 1-6, ISSN: 2314-4920, DOI: 10.1155/2017/9253475 |
Journal of Spectroscopy 2017 | 2020-02-21 |
| 2017 |
Matthias Eibl, Sebastian Karpf, Hubertus Hakert, Daniel Weng, Torben Blömker, Robert Huber Pulse-to-pulse wavelength switching of diode based fiber laser for multi-color multi-photon imaging published pages: 100831C, ISSN: , DOI: 10.1117/12.2251965 |
Fiber Lasers XIV: Technology and Systems | 2020-02-21 |
| 2016 |
Robert Huber, Lars Dworak, Jacques E. Moser, Michael Grätzel, Josef Wachtveitl Beyond Vibrationally Mediated Electron Transfer: Coherent Phenomena Induced by Ultrafast Charge Separation published pages: 8534-8539, ISSN: 1932-7447, DOI: 10.1021/acs.jpcc.6b02012 |
The Journal of Physical Chemistry C 120/16 | 2020-02-21 |
| 2016 |
Jan Philip Kolb, Thomas Klein, Matthias Eibl, Tom Pfeiffer, Wolfgang Wieser, Robert Huber Megahertz FDML laser with up to 143nm sweep range for ultrahigh resolution OCT at 1050nm published pages: 969703, ISSN: , DOI: 10.1117/12.2214758 |
Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XX | 2020-02-21 |
| 2017 |
Tom Pfeiffer, Wolfgang Draxinger, Wolfgang Wieser, Thomas Klein, Markus Petermann, Robert Huber Analysis of FDML lasers with meter range coherence published pages: 100531T, ISSN: , DOI: 10.1117/12.2254792 |
Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XXI | 2020-02-21 |
| 2017 |
Max-Heinrich Laves, Andreas Schoob, Lüder A. Kahrs, Tom Pfeiffer, Robert Huber, Tobias Ortmaier Feature tracking for automated volume of interest stabilization on 4D-OCT images published pages: 101350W, ISSN: , DOI: 10.1117/12.2255090 |
Medical Imaging 2017: Image-Guided Procedures, Robotic Interventions, and Modeling | 2020-02-21 |
| 2016 |
Tianshi Wang, Tom Pfeiffer, Evelyn Regar, Wolfgang Wieser, Heleen van Beusekom, Charles T. Lancee, Geert Springeling, Ilona Krabbendam-Peters, Antonius F.W. van der Steen, Robert Huber, Gijs van Soest Heartbeat OCT and Motion-Free 3D In Vivo Coronary Artery Microscopy published pages: 622-623, ISSN: 1936-878X, DOI: 10.1016/j.jcmg.2015.08.010 |
JACC: Cardiovascular Imaging 9/5 | 2020-02-21 |
Are you the coordinator (or a participant) of this project? Plaese send me more information about the "ENCOMOLE-2I" project.
For instance: the website url (it has not provided by EU-opendata yet), the logo, a more detailed description of the project (in plain text as a rtf file or a word file), some pictures (as picture files, not embedded into any word file), twitter account, linkedin page, etc.
Send me an email (fabio@fabiodisconzi.com) and I put them in your project's page as son as possible.
Thanks. And then put a link of this page into your project's website.
The information about "ENCOMOLE-2I" are provided by the European Opendata Portal: CORDIS opendata.