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DNAmics SIGNED

DNA mimetics: Synthetic molecular duplexes

Total Cost €

EC-Contrib. €

Partnership

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Outcomes and
results

DNAmics project word cloud

Explore the words cloud of the DNAmics project. It provides you a very rough idea of what is the project "DNAmics" about.

sites molecular smart precise desired adding dna give predictability valuable recognition sequences oligomeric chemical photochemical words biggest science defective nonliving sequence performed modular modern supramolecular explore prepared unprecedented duplex assembly mechanical will fidelity duplexes form complementary programmability components foundation living synthesis preparation multivalent synthetic flexible basic organizes robustness inspired imperfections lay quantitative bonding biological accomplishes structural macroscopic nature interactions reliability materials fascinating electronic

Project "DNAmics" data sheet

The following table provides information about the project.

Coordinator	THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE Organization address address: TRINITY LANE THE OLD SCHOOLS city: CAMBRIDGE postcode: CB2 1TN website: www.cam.ac.uk contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.
Coordinator Country	United Kingdom [UK]
Project website	https://www.ch.cam.ac.uk/person/pt379
Total cost	195˙454 €
EC max contribution	195˙454 € (100%)
Programme	1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
Code Call	H2020-MSCA-IF-2014
Funding Scheme	MSCA-IF-EF-ST
Starting year	2016
Duration (year-month-day)	from 2016-01-01 to 2017-12-31

Partnership

Take a look of project's partnership.

#	participants	country	role	EC contrib. [€]
1	THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE Organization address address: TRINITY LANE THE OLD SCHOOLS city: CAMBRIDGE postcode: CB2 1TN website: www.cam.ac.uk contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	UK (CAMBRIDGE)	coordinator	195˙454.00

Map

Project objective

Precise control of macroscopic properties at molecular level is one of the biggest challenges of modern science. Nature accomplishes this by adding information to matter, and organizes chemical system of nonliving components into living, biological systems. Inspired by the most fascinating nature’s information system, the DNA, and using its basic structural elements, modular and highly flexible synthesis of novel chemical information carrying system will be performed. This will enable the preparation of the desired sequence of H-bonding recognition sites. The prepared short oligomeric sequences will be used to explore robustness of synthetic sequences for the formation of duplexes. By quantitative assessment of multivalent recognition of complementary sequences and imperfections in the duplex formation of non-complementary and defective sequences, valuable information on the structural features and fidelity of supramolecular assembly formation of various sequences will be obtained. This will give insight into reliability and predictability, in other words programmability, of the proposed synthetic recognition sequences to form molecular duplexes. Reliable formation of synthetic duplexes would allow precise control over supramolecular interactions and will lay the foundation for formation of smart advanced materials with unprecedented mechanical, electronic and photochemical properties.

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The information about "DNAMICS" are provided by the European Opendata Portal: CORDIS opendata.