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PROTEOMICS4D SIGNED
Proteomics 4D: The proteome in context
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Explore the words cloud of the PROTEOMICS4D project. It provides you a very rough idea of what is the project "PROTEOMICS4D" about.
wgs
seemingly
quantitative
multiple
mutations
interacting
tissue
wild
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tenants
notion
cryoem
technologies
generate
hybrid
spectrometry
relate
topology
integrate
few
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chemical
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proteomic
structural
comprehensively
disease
mechanistic
base
modules
data
elusive
independent
proteins
variants
transformation
phenotypes
context
molecular
elements
entity
perturbation
basic
linking
gwas
broad
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cross
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single
phosphoproteomic
genetic
genomic
disseminated
functional
protein
mass
computational
modular
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supporting
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medicine
biochemical
epigenetic
perturbed
initially
generalize
kinase
proteome
composition
genetically
cancer
transcriptomics
catalyze
4d
arise
biology
explores
probe
science
integration
consisting
Project "PROTEOMICS4D" data sheet
The following table provides information about the project.
| Coordinator |
EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH
Organization address contact info |
| Coordinator Country | Switzerland [CH] |
| Project website | http://www.imsb.ethz.ch/research/aebersold.html |
| Total cost | 2˙208˙150 € |
| EC max contribution | 2˙208˙150 € (100%) |
| Programme |
1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC)) |
| Code Call | ERC-2014-ADG |
| Funding Scheme | ERC-ADG |
| Starting year | 2015 |
| Duration (year-month-day) | from 2015-09-01 to 2020-08-31 |
Partnership
Take a look of project's partnership.
| # | ||||
|---|---|---|---|---|
| 1 | EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH | CH (ZUERICH) | coordinator | 2˙208˙150.00 |
Map
Project objective
Elements operating in the context of a system generate results that are different from the simple addition of the results of each element. This notion is one of the basic tenants of systems science. In systems biology/medicine complex (disease) phenotypes arise from multiple interacting factors, specifically proteins. Yet, the biochemical and mechanistic base of complex phenotypes remain elusive. An array of powerful genomic technologies including GWAS, WGS, transcriptomics, epigenetic analyses and proteomics have identified numerous factors that contribute to complex phenotypes. It can be expected that over the next few years, genetic factors contributing to specific complex phenotypes will be comprehensively identified, while their interactions will remain elusive. The project “Proteomics 4D: The proteome in context “explores the concept, that complex phenotypes arise from the perturbation of modules of interacting proteins and that these modules integrate seemingly independent genomic variants into a single biochemical response. We will develop and apply a generic technology to directly measure the composition, topology and structure of wild type and genetically perturbed protein modules and relate structural changes to their functional output. This will be achieved by a the integration of quantitative proteomic and phosphoproteomic technologies determining molecular phenotypes, and hybrid structural methods consisting of chemical cross-linking and mass spectrometry, cryoEM and computational data integration to probe structural perturbations. The project will focus initially on the structural and functional effects of cancer associated mutations in protein kinase modules and then generalize to study perturbed modules in any tissue and disease state. The resources supporting this technology will be disseminated to catalyze a broad transformation of biology and molecular medicine towards the analysis of the proteome as a modular entity, the proteome in context.
Publications
| year | authors and title | journal | last update |
|---|---|---|---|
| 2018 |
Saikat Chowdhury, Chinatsu Otomo, Alexander Leitner, Kazuto Ohashi, Ruedi Aebersold, Gabriel C. Lander, Takanori Otomo Insights into autophagosome biogenesis from structural and biochemical analyses of the ATG2A-WIPI4 complex published pages: E9792-E9801, ISSN: 0027-8424, DOI: 10.1073/pnas.1811874115 |
Proceedings of the National Academy of Sciences 115/42 | 2020-04-15 |
| 2019 |
Helleboid, Pierre-Yves; Heusel, Moritz; Duc, Julien; Piot, Cecile; Thorball, Christian W.; Coluccio, Andrea; Pontis, Julien; Turelli, Priscilla; Aebersold, Ruedi; Trono, Didier The interactome of KRAB zinc finger proteins reveals the evolutionary history of their functional diversification published pages: , ISSN: 0261-4189, DOI: 10.3929/ethz-b-000360670 |
The EMBO Journal, 38 (18) 2 | 2020-04-15 |
| 2019 |
Guo, T.; Luna, A.; Rajapakse, V.N.; Koh, C.C.; Wu, Z.; Liu, W.; Sun, Y.; Gao, H.; Menden, M.P.; Xu, C.; Calzone, L.; Martignetti, L.; Auwerx, C.; Buljan, M.; Banaei-Esfahani, A.; Ori, A.; Iskar, M.; Gillet, L.; Bi, R.; Zhang, J.; Zhang, H.; Yu, C.; Zhong, Q.; Varma, S.; Schmitt, U.; Qiu, P.; Zhang, Q.; Zhu, Y.; Wild, P.J.; Garnett, M.J.; Bork, P.; Beck, M.; Liu, K.; Saez-Rodriguez, J.; Elloumi, F. Quantitative Proteome Landscape of the NCI-60 Cancer Cell Lines published pages: , ISSN: 1538-8514, DOI: 10.3929/ethz-b-000378057 |
iScience, 21 5 | 2020-04-15 |
| 2018 |
Yi Zhu, Jiang Zhu, Cong Lu, Qiushi Zhang, Wei Xie, Ping Sun, Xiaochuan Dong, Liang Yue, Yaoting Sun, Xiao Yi, Tiansheng Zhu, Guan Ruan, Ruedi Aebersold, Shi\'ang Huang, Tiannan Guo Identification of Protein Abundance Changes in Hepatocellular Carcinoma Tissues Using PCT–SWATH published pages: 1700179, ISSN: 1862-8346, DOI: 10.1002/prca.201700179 |
PROTEOMICS – Clinical Applications 13/1 | 2020-04-15 |
| 2019 |
Natalie Romanov, Michael Kuhn, Ruedi Aebersold, Alessandro Ori, Martin Beck, Peer Bork Disentangling Genetic and Environmental Effects on the Proteotypes of Individuals published pages: 1308-1318.e10, ISSN: 0092-8674, DOI: 10.1016/j.cell.2019.03.015 |
Cell 177/5 | 2020-04-15 |
| 2019 |
Shao, Wenguang; Guo, Tiannan; Toussaint, Nora C.; Xue, Peng; Wagner, Ulrich; Li, Li; Charmpi, Konstantina; Zhu, Yi; Wu, Jianmin; Buljan, Marija; Sun, Rui; Rutishauser, Dorothea; Hermanns, Thomas; Fankhauser, Christian Daniel; Poyet, Cedric; Ljubicic, Jelena; Rupp, Niels; Rüschoff, Jan H.; Zhong, Qing; Beyer, Andreas; Ji, Jiafu; Collins, Ben C.; Liu, Yansheng; Rätsch, Gunnar; Wild, Peter J.; Aebe Comparative analysis of mRNA and protein degradation in prostate tissues indicates high stability of proteins published pages: , ISSN: 2041-1723, DOI: 10.5167/uzh-171764 |
Shao, Wenguang <javascript:contributorCitation( \'Shao, Wenguang\' );>; Guo, Tiannan <javascript:contributorCitation( \'Guo, Tiannan\' );>; Toussaint, Nora C <javascript:contributorCitation( \'Toussaint, Nora C\' );>; Xue, Peng <javascript:contributorCitation( \'Xue, Peng\' );>; Wagner, Ulrich <javascript:contributorCitation( \'Wagner, Ulrich\' );>; Li, Li <javascript:contri 8 | 2020-04-15 |
| 2020 |
Marte Molenaars, Georges E. Janssens, Evan G. Williams, Aldo Jongejan, Jiayi Lan, Sylvie Rabot, Fatima Joly, Perry D. Moerland, Bauke V. Schomakers, Marco Lezzerini, Yasmine J. Liu, Mark A. McCormick, Brian K. Kennedy, Michel van Weeghel, Antoine H.C. van Kampen, Ruedi Aebersold, Alyson W. MacInnes, Riekelt H. Houtkooper A Conserved Mito-Cytosolic Translational Balance Links Two Longevity Pathways published pages: 549-563.e7, ISSN: 1550-4131, DOI: 10.1016/j.cmet.2020.01.011 |
Cell Metabolism 31/3 | 2020-04-15 |
| 2020 |
Rodrigo Villaseñor, Ramon Pfaendler, Christina Ambrosi, Stefan Butz, Sara Giuliani, Elana Bryan, Thomas W. Sheahan, Annika L. Gable, Nina Schmolka, Massimiliano Manzo, Joël Wirz, Christian Feller, Christian von Mering, Ruedi Aebersold, Philipp Voigt, Tuncay Baubec ChromID identifies the protein interactome at chromatin marks published pages: , ISSN: 1087-0156, DOI: 10.1038/s41587-020-0434-2 |
Nature Biotechnology | 2020-04-15 |
| 2019 |
Daniel Gestaut, Soung Hun Roh, Boxue Ma, Grigore Pintilie, Lukasz A. Joachimiak, Alexander Leitner, Thomas Walzthoeni, Ruedi Aebersold, Wah Chiu, Judith Frydman The Chaperonin TRiC/CCT Associates with Prefoldin through a Conserved Electrostatic Interface Essential for Cellular Proteostasis published pages: 751-765.e15, ISSN: 0092-8674, DOI: 10.1016/j.cell.2019.03.012 |
Cell 177/3 | 2020-04-15 |
| 2019 |
Yansheng Liu, Yang Mi, Torsten Mueller, Saskia Kreibich, Evan G. Williams, Audrey Van Drogen, Christelle Borel, Max Frank, Pierre-Luc Germain, Isabell Bludau, Martin Mehnert, Michael Seifert, Mario Emmenlauer, Isabel Sorg, Fedor Bezrukov, Frederique Sloan Bena, Hu Zhou, Christoph Dehio, Giuseppe Testa, Julio Saez-Rodriguez, Stylianos E. Antonarakis, Wolf-Dietrich Hardt, Ruedi Aebersold Multi-omic measurements of heterogeneity in HeLa cells across laboratories published pages: 314-322, ISSN: 1087-0156, DOI: 10.1038/s41587-019-0037-y |
Nature Biotechnology 37/3 | 2020-04-15 |
| 2019 |
Peter Blattmann, Vivienne Stutz, Giulia Lizzo, Joy Richard, Philipp Gut, Ruedi Aebersold Generation of a zebrafish SWATH-MS spectral library to quantify 10,000 proteins published pages: , ISSN: 2052-4463, DOI: 10.1038/sdata.2019.11 |
Scientific Data 6/1 | 2020-04-15 |
| 2019 |
Javier Celis-Gutierrez, Peter Blattmann, Yunhao Zhai, Nicolas Jarmuzynski, Kilian Ruminski, Claude Grégoire, Youcef Ounoughene, Frédéric Fiore, Ruedi Aebersold, Romain Roncagalli, Matthias Gstaiger, Bernard Malissen Quantitative Interactomics in Primary T Cells Provides a Rationale for Concomitant PD-1 and BTLA Coinhibitor Blockade in Cancer Immunotherapy published pages: 3315-3330.e7, ISSN: 2211-1247, DOI: 10.1016/j.celrep.2019.05.041 |
Cell Reports 27/11 | 2020-04-15 |
| 2019 |
Pavel Bouchal, Olga T. Schubert, Jakub Faktor, Lenka Capkova, Hana Imrichova, Karolina Zoufalova, Vendula Paralova, Roman Hrstka, Yansheng Liu, Holger Alexander Ebhardt, Eva Budinska, Rudolf Nenutil, Ruedi Aebersold Breast Cancer Classification Based on Proteotypes Obtained by SWATH Mass Spectrometry published pages: 832-843.e7, ISSN: 2211-1247, DOI: 10.1016/j.celrep.2019.06.046 |
Cell Reports 28/3 | 2020-04-15 |
| 2020 |
Moritz Heusel, Max Frank, Mario Köhler, Sabine Amon, Fabian Frommelt, George Rosenberger, Isabell Bludau, Simran Aulakh, Monika I. Linder, Yansheng Liu, Ben C. Collins, Matthias Gstaiger, Ulrike Kutay, Ruedi Aebersold A Global Screen for Assembly State Changes of the Mitotic Proteome by SEC-SWATH-MS published pages: 133-155.e6, ISSN: 2405-4712, DOI: 10.1016/j.cels.2020.01.001 |
Cell Systems 10/2 | 2020-04-15 |
| 2019 |
Alexander Schäfer, Enio Gjerga, Richard WD Welford, Imke Renz, Francois Lehembre, Peter MA Groenen, Julio Saezâ€Rodriguez, Ruedi Aebersold, Matthias Gstaiger Elucidating essential kinases of endothelin signalling by logic modelling of phosphoproteomics data published pages: , ISSN: 1744-4292, DOI: 10.15252/msb.20198828 |
Molecular Systems Biology 15/8 | 2020-04-15 |
| 2019 |
Sabine Amon, Fabienne Meier-Abt, Ludovic C. Gillet, Slavica Dimitrieva, Alexandre P. A. Theocharides, Markus G. Manz, Ruedi Aebersold Sensitive Quantitative Proteomics of Human Hematopoietic Stem and Progenitor Cells by Data-independent Acquisition Mass Spectrometry published pages: 1454-1467, ISSN: 1535-9476, DOI: 10.1074/mcp.TIR119.001431 |
Molecular & Cellular Proteomics 18/7 | 2020-04-15 |
| 2019 |
Ruedi Aebersold, Peter Blattmann Mass Spectrometric Exploration of the Biochemical Basis of Living Systems published pages: 540-548, ISSN: 0009-4293, DOI: 10.2533/chimia.2019.540 |
CHIMIA International Journal for Chemistry 73/7 | 2020-04-15 |
| 2019 |
Moritz Heusel, Isabell Bludau, George Rosenberger, Robin Hafen, Max Frank, Amir Banaeiâ€Esfahani, Audrey Drogen, Ben C Collins, Matthias Gstaiger, Ruedi Aebersold Complexâ€centric proteome profiling by SEC †SWATH †MS published pages: , ISSN: 1744-4292, DOI: 10.15252/msb.20188438 |
Molecular Systems Biology 15/1 | 2020-04-15 |
| 2019 |
Lilia Kaustov, Alexander Lemak, Hong Wu, Marco Faini, Lixin Fan, Xianyang Fang, Hong Zeng, Shili Duan, Abdellah Allali-Hassani, Fengling Li, Yong Wei, Masoud Vedadi, Ruedi Aebersold, Yunxing Wang, Scott Houliston, Cheryl H Arrowsmith The MLL1 trimeric catalytic complex is a dynamic conformational ensemble stabilized by multiple weak interactions published pages: , ISSN: 0305-1048, DOI: 10.1093/nar/gkz697 |
Nucleic Acids Research | 2020-04-15 |
| 2016 |
Hirokazu Okada, H. Alexander Ebhardt, Sibylle Chantal Vonesch, Ruedi Aebersold, Ernst Hafen Proteome-wide association studies identify biochemical modules associated with a wing-size phenotype in Drosophila melanogaster published pages: 12649, ISSN: 2041-1723, DOI: 10.1038/ncomms12649 |
Nature Communications 7 | 2019-07-05 |
| 2016 |
Yansheng Liu, Andreas Beyer, Ruedi Aebersold On the Dependency of Cellular Protein Levels on mRNA Abundance published pages: 535-550, ISSN: 0092-8674, DOI: 10.1016/j.cell.2016.03.014 |
Cell 165/3 | 2019-07-05 |
| 2016 |
Ulrike Kusebauch, David S. Campbell, Eric W. Deutsch, Caroline S. Chu, Douglas A. Spicer, Mi-Youn Brusniak, Joseph Slagel, Zhi Sun, Jeffrey Stevens, Barbara Grimes, David Shteynberg, Michael R. Hoopmann, Peter Blattmann, Alexander V. Ratushny, Oliver Rinner, Paola Picotti, Christine Carapito, Chung-Ying Huang, Meghan Kapousouz, Henry Lam, Tommy Tran, Emek Demir, John D. Aitchison, Chris Sander, Le Human SRMAtlas: A Resource of Targeted Assays to Quantify the Complete Human Proteome published pages: 766-778, ISSN: 0092-8674, DOI: 10.1016/j.cell.2016.06.041 |
Cell 166/3 | 2019-07-05 |
| 2016 |
Hannes L Röst, Yansheng Liu, Giuseppe D\'Agostino, Matteo Zanella, Pedro Navarro, George Rosenberger, Ben C Collins, Ludovic Gillet, Giuseppe Testa, Lars Malmström, Ruedi Aebersold TRIC: an automated alignment strategy for reproducible protein quantification in targeted proteomics published pages: 777-783, ISSN: 1548-7091, DOI: 10.1038/nmeth.3954 |
Nature Methods 13/9 | 2019-07-05 |
| 2017 |
Blattmann, Peter; Henriques, David; Zimmermann, Michael; Frommelt, Fabian; Sauer, Uwe; Saez-Rodriguez, Julio; Aebersold, Ruedi Systems Pharmacology Dissection of Cholesterol Regulation Reveals Determinants of Large Pharmacodynamic Variability between Cell Lines published pages: , ISSN: 2405-4712, DOI: 10.3929/ethz-b-000228208 |
Cell Systems 11 | 2019-07-05 |
| 2016 |
E. G. Williams, Y. Wu, P. Jha, S. Dubuis, P. Blattmann, C. A. Argmann, S. M. Houten, T. Amariuta, W. Wolski, N. Zamboni, R. Aebersold, J. Auwerx Systems proteomics of liver mitochondria function published pages: aad0189-aad0189, ISSN: 0036-8075, DOI: 10.1126/science.aad0189 |
Science 352/6291 | 2019-07-05 |
| 2018 |
Buljan, Marija; Blattmann, Peter; Aebersold, Ruedi; Boutros, Michael Systematic characterization of panâ€cancer mutation clusters published pages: , ISSN: 1744-4292, DOI: 10.3929/ethz-b-000256182 |
Molecular Systems Biology 1 | 2019-07-05 |
| 2017 |
George Rosenberger, Yansheng Liu, Hannes L Röst, Christina Ludwig, Alfonso Buil, Ariel Bensimon, Martin Soste, Tim D Spector, Emmanouil T Dermitzakis, Ben C Collins, Lars Malmström, Ruedi Aebersold Inference and quantification of peptidoforms in large sample cohorts by SWATH-MS published pages: 781-788, ISSN: 1087-0156, DOI: 10.1038/nbt.3908 |
Nature Biotechnology 35/8 | 2019-07-05 |
| 2016 |
Pedro Navarro, Jörg Kuharev, Ludovic C Gillet, Oliver M Bernhardt, Brendan MacLean, Hannes L Röst, Stephen A Tate, Chih-Chiang Tsou, Lukas Reiter, Ute Distler, George Rosenberger, Yasset Perez-Riverol, Alexey I Nesvizhskii, Ruedi Aebersold, Stefan Tenzer A multicenter study benchmarks software tools for label-free proteome quantification published pages: 1130-1136, ISSN: 1087-0156, DOI: 10.1038/nbt.3685 |
Nature Biotechnology 34/11 | 2019-07-05 |
| 2017 |
Xiaorong Wang, Peter Cimermancic, Clinton Yu, Andreas Schweitzer, Nikita Chopra, James L. Engel, Charles H Greenberg, Alexander S Huszagh, Florian Beck, Eri Sakata, Yingying Yang, Eric J Novitsky, Alexander Leitner, Paolo Nanni, Abdullah Kahraman, Xing Guo, Jack E Dixon, Scott D Rychnovsky, Ruedi Aebersold, Wolfgang Baumeister, Andrej Sali, Lan Huang Molecular Details Underlying Dynamic Structures and Regulation of the Human 26S Proteasome published pages: mcp.M116.065326, ISSN: 1535-9476, DOI: 10.1074/mcp.M116.065326 |
Molecular & Cellular Proteomics | 2019-07-05 |
| 2017 |
Yansheng Liu, Mar Gonzà lez-Porta, Sergio Santos, Alvis Brazma, John C. Marioni, Ruedi Aebersold, Ashok R. Venkitaraman, Vihandha O. Wickramasinghe Impact of Alternative Splicing on the Human Proteome published pages: 1229-1241, ISSN: 2211-1247, DOI: 10.1016/j.celrep.2017.07.025 |
Cell Reports 20/5 | 2019-04-18 |
| 2017 |
Olga T Schubert, Hannes L Röst, Ben C Collins, George Rosenberger, Ruedi Aebersold Quantitative proteomics: challenges and opportunities in basic and applied research published pages: 1289-1294, ISSN: 1754-2189, DOI: 10.1038/nprot.2017.040 |
Nature Protocols 12/7 | 2019-04-18 |
| 2018 |
Sabina Schütz, Erich Michel, Fred F. Damberger, Michaela Oplová, Cohue Peña, Alexander Leitner, Ruedi Aebersold, Frederic H.-T. Allain, Vikram Govind Panse Molecular basis for disassembly of an importin:ribosomal protein complex by the escortin Tsr2 published pages: , ISSN: 2041-1723, DOI: 10.1038/s41467-018-06160-x |
Nature Communications 9/1 | 2019-04-18 |
| 2016 |
Simon Schwörer, Friedrich Becker, Christian Feller, Ali H. Baig, Ute Köber, Henriette Henze, Johann M. Kraus, Beibei Xin, André Lechel, Daniel B. Lipka, Christy S. Varghese, Manuel Schmidt, Remo Rohs, Ruedi Aebersold, Kay L. Medina, Hans A. Kestler, Francesco Neri, Julia von Maltzahn, Stefan Tümpel, K. Lenhard Rudolph Epigenetic stress responses induce muscle stem-cell ageing by Hoxa9 developmental signals published pages: 428-432, ISSN: 0028-0836, DOI: 10.1038/nature20603 |
Nature 540/7633 | 2019-04-18 |
| 2017 |
Daniel P Zolg, Mathias Wilhelm, Karsten Schnatbaum, Johannes Zerweck, Tobias Knaute, Bernard Delanghe, Derek J Bailey, Siegfried Gessulat, Hans-Christian Ehrlich, Maximilian Weininger, Peng Yu, Judith Schlegl, Karl Kramer, Tobias Schmidt, Ulrike Kusebauch, Eric W Deutsch, Ruedi Aebersold, Robert L Moritz, Holger Wenschuh, Thomas Moehring, Stephan Aiche, Andreas Huhmer, Ulf Reimer, Bernhard Kuster Building ProteomeTools based on a complete synthetic human proteome published pages: 259-262, ISSN: 1548-7091, DOI: 10.1038/NMETH.4153 |
Nature Methods 14/3 | 2019-04-18 |
| 2018 |
Vignesh Kasinath, Marco Faini, Simon Poepsel, Dvir Reif, Xinyu Ashlee Feng, Goran Stjepanovic, Ruedi Aebersold, Eva Nogales Structures of human PRC2 with its cofactors AEBP2 and JARID2 published pages: 940-944, ISSN: 0036-8075, DOI: 10.1126/science.aar5700 |
Science 359/6378 | 2019-04-18 |
| 2016 |
Terfve C, Sabidó E, Wu Y, Gonçalves E, Choi M, Vaga S, Vitek O, Saez-Rodriguez J, Aebersold R. System-wide quantitative proteomics of the metabolic syndrome in mice: genotypic and dietary effects published pages: , ISSN: 1535-3893, DOI: |
Journal of Proteome Research | 2019-04-18 |
| 2018 |
Christina Ludwig, Ludovic Gillet, George Rosenberger, Sabine Amon, Ben C Collins, Ruedi Aebersold Dataâ€independent acquisitionâ€based SWATHâ€MS for quantitative proteomics: a tutorial published pages: e8126, ISSN: 1744-4292, DOI: 10.15252/msb.20178126 |
Molecular Systems Biology 14/8 | 2019-04-18 |
| 2017 |
Marcello Clerici, Marco Faini, Ruedi Aebersold, Martin Jinek Structural insights into the assembly and polyA signal recognition mechanism of the human CPSF complex published pages: , ISSN: 2050-084X, DOI: 10.7554/eLife.33111 |
eLife 6 | 2019-04-18 |
| 2017 |
Etienne Caron, Romain Roncagalli, Takeshi Hase, Witold E. Wolski, Meena Choi, Marisa G. Menoita, Stephane Durand, Antonio GarcÃa-Blesa, Ivo Fierro-Monti, Tatjana Sajic, Moritz Heusel, Tobias Weiss, Marie Malissen, Ralph Schlapbach, Ben C. Collins, Samik Ghosh, Hiroaki Kitano, Ruedi Aebersold, Bernard Malissen, Matthias Gstaiger Precise Temporal Profiling of Signaling Complexes in Primary Cells Using SWATH Mass Spectrometry published pages: 3219-3226, ISSN: 2211-1247, DOI: 10.1016/j.celrep.2017.03.019 |
Cell Reports 18/13 | 2019-04-18 |
| 2018 |
Julia Hülsmann, Bojana Kravic, Matthias Weith, Matthias Gstaiger, Ruedi Aebersold, Ben C. Collins, Hemmo Meyer AP-SWATH Reveals Direct Involvement of VCP/p97 in Integrated Stress Response Signaling Through Facilitating CReP/PPP1R15B Degradation published pages: 1295-1307, ISSN: 1535-9476, DOI: 10.1074/mcp.RA117.000471 |
Molecular & Cellular Proteomics 17/7 | 2019-04-18 |
| 2017 |
Wenguang Shao, Henry Lam Tandem mass spectral libraries of peptides and their roles in proteomics research published pages: 634-648, ISSN: 0277-7037, DOI: 10.1002/mas.21512 |
Mass Spectrometry Reviews 36/5 | 2019-04-18 |
| 2017 |
Hannes L. Röst, Ruedi Aebersold, Olga T. Schubert Automated SWATH Data Analysis Using Targeted Extraction of Ion Chromatograms published pages: 289-307, ISSN: , DOI: 10.1007/978-1-4939-6747-6_20 |
Proteomics: Methods and Protocols | 2019-04-18 |
| 2018 |
Christian Feller, Ruedi Aebersold A Proteomic Connectivity Map published pages: 403-405, ISSN: 2405-4712, DOI: 10.1016/j.cels.2018.04.007 |
Cell Systems 6/4 | 2019-04-18 |
| 2018 |
Jungmin Yoon, Seung Joong Kim, Sojin An, Saehyun Cho, Alexander Leitner, Taeyang Jung, Ruedi Aebersold, Hans Hebert, Uhn-Soo Cho, Ji-Joon Song Integrative Structural Investigation on the Architecture of Human Importin4_Histone H3/H4_Asf1a Complex and Its Histone H3 Tail Binding published pages: 822-841, ISSN: 0022-2836, DOI: 10.1016/j.jmb.2018.01.015 |
Journal of Molecular Biology 430/6 | 2019-04-18 |
| 2018 |
Evan G. Williams, Yibo Wu, Witold Wolski, Jun Yong Kim, Jiayi Lan, Moaraj Hasan, Christian Halter, Pooja Jha, Dongryeol Ryu, Johan Auwerx, Ruedi Aebersold Quantifying and Localizing the Mitochondrial Proteome Across Five Tissues in A Mouse Population published pages: 1766-1777, ISSN: 1535-9476, DOI: 10.1074/mcp.RA118.000554 |
Molecular & Cellular Proteomics 17/9 | 2019-04-18 |
| 2017 |
Yansheng Liu, Christelle Borel, Li Li, Torsten Müller, Evan G. Williams, Pierre-Luc Germain, Marija Buljan, Tatjana Sajic, Paul J. Boersema, Wenguang Shao, Marco Faini, Giuseppe Testa, Andreas Beyer, Stylianos E. Antonarakis, Ruedi Aebersold Systematic proteome and proteostasis profiling in human Trisomy 21 fibroblast cells published pages: , ISSN: 2041-1723, DOI: 10.1038/s41467-017-01422-6 |
Nature Communications 8/1 | 2019-04-18 |
| 2018 |
Boris Eliseev, Lahari Yeramala, Alexander Leitner, Manikandan Karuppasamy, Etienne Raimondeau, Karine Huard, Elena Alkalaeva, Ruedi Aebersold, Christiane Schaffitzel Structure of a human cap-dependent 48S translation pre-initiation complex published pages: 2678-2689, ISSN: 0305-1048, DOI: 10.1093/nar/gky054 |
Nucleic Acids Research 46/5 | 2019-04-18 |
| 2017 |
Neha Patel, Florian Stengel, Ruedi Aebersold, Matthew G. Gold Molecular basis of AKAP79 regulation by calmodulin published pages: , ISSN: 2041-1723, DOI: 10.1038/s41467-017-01715-w |
Nature Communications 8/1 | 2019-04-18 |
| 2017 |
George Rosenberger, Isabell Bludau, Uwe Schmitt, Moritz Heusel, Christie L Hunter, Yansheng Liu, Michael J MacCoss, Brendan X MacLean, Alexey I Nesvizhskii, Patrick G A Pedrioli, Lukas Reiter, Hannes L Röst, Stephen Tate, Ying S Ting, Ben C Collins, Ruedi Aebersold Statistical control of peptide and protein error rates in large-scale targeted data-independent acquisition analyses published pages: 921-927, ISSN: 1548-7091, DOI: 10.1038/NMETH.4398 |
Nature Methods 14/9 | 2019-04-18 |
| 2017 |
Ben C. Collins, Christie L. Hunter, Yansheng Liu, Birgit Schilling, George Rosenberger, Samuel L. Bader, Daniel W. Chan, Bradford W. Gibson, Anne-Claude Gingras, Jason M. Held, Mio Hirayama-Kurogi, Guixue Hou, Christoph Krisp, Brett Larsen, Liang Lin, Siqi Liu, Mark P. Molloy, Robert L. Moritz, Sumio Ohtsuki, Ralph Schlapbach, Nathalie Selevsek, Stefani N. Thomas, Shin-Cheng Tzeng, Hui Zhang, Ruedi Aebersold Multi-laboratory assessment of reproducibility, qualitative and quantitative performance of SWATH-mass spectrometry published pages: , ISSN: 2041-1723, DOI: 10.1038/s41467-017-00249-5 |
Nature Communications 8/1 | 2019-04-18 |
| 2018 |
Marcello Clerici, Marco Faini, Lena M. Muckenfuss, Ruedi Aebersold, Martin Jinek Author Correction: Structural basis of AAUAAA polyadenylation signal recognition by the human CPSF complex published pages: 355-355, ISSN: 1545-9993, DOI: 10.1038/s41594-018-0044-6 |
Nature Structural & Molecular Biology 25/4 | 2019-04-18 |
| 2017 |
Georg Dorn, Alexander Leitner, Julien Boudet, Sébastien Campagne, Christine von Schroetter, Ahmed Moursy, Ruedi Aebersold, Frédéric H-T Allain Structural modeling of protein–RNA complexes using crosslinking of segmentally isotope-labeled RNA and MS/MS published pages: 487-490, ISSN: 1548-7091, DOI: 10.1038/NMETH.4235 |
Nature Methods 14/5 | 2019-04-18 |
Are you the coordinator (or a participant) of this project? Plaese send me more information about the "PROTEOMICS4D" project.
For instance: the website url (it has not provided by EU-opendata yet), the logo, a more detailed description of the project (in plain text as a rtf file or a word file), some pictures (as picture files, not embedded into any word file), twitter account, linkedin page, etc.
Send me an email (fabio@fabiodisconzi.com) and I put them in your project's page as son as possible.
Thanks. And then put a link of this page into your project's website.
The information about "PROTEOMICS4D" are provided by the European Opendata Portal: CORDIS opendata.