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FutForm SIGNED

Future Formulations: Developing Future Pharmaceuticals Through Advanced Analysis and Intersectoral Exchange

Total Cost €

EC-Contrib. €

Partnership

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Outcomes and
results

FutForm project word cloud

Explore the words cloud of the FutForm project. It provides you a very rough idea of what is the project "FutForm" about.

post expensive companies secondments stage abiel uon dosage focussed approval medium 145 877 platform portugal billion netherlands intersectoral technologies directed regimens 2 innovative supporting strengths chance nature enterprise pharmacy oral university additional indications times drug later isolation small cell sme hydrogel therapies predict gt nanoparticle excess principal actives hy2care formulations enzyme 13 exchange analytical approx industry 300 translate surface optimize tools italy nottingham collaborative researcher school inovapotek biophysical market million reducing medicine phases industrial 2014 reviews futform earlier pharmaceutical discovery lda 2003 topical reflect

Project "FutForm" data sheet

The following table provides information about the project.

Coordinator	THE UNIVERSITY OF NOTTINGHAM Organization address address: University Park city: NOTTINGHAM postcode: NG7 2RD website: www.nottingham.ac.uk contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.
Coordinator Country	United Kingdom [UK]
Project website	http://www.nottingham.ac.uk/futformrise/
Total cost	414˙000 €
EC max contribution	414˙000 € (100%)
Programme	1. H2020-EU.1.3.3. (Stimulating innovation by means of cross-fertilisation of knowledge)
Code Call	H2020-MSCA-RISE-2015
Funding Scheme	MSCA-RISE
Starting year	2016
Duration (year-month-day)	from 2016-04-01 to 2020-03-31

Partnership

Take a look of project's partnership.

#	participants	country	role	EC contrib. [€]
1	THE UNIVERSITY OF NOTTINGHAM THE UNIVERSITY OF NOTTINGHAM Organization address address: University Park city: NOTTINGHAM postcode: NG7 2RD website: www.nottingham.ac.uk contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	UK (NOTTINGHAM)	coordinator	297˙000.00
2	HY2CARE BV HY2CARE BV Organization address address: Drienerlolaan 5, ZH143 city: ENSCHEDE postcode: 7522 NB website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	NL (ENSCHEDE)	participant	54˙000.00
3	INOVAPOTEK, PHARMACEUTICAL RESEARCH AND DEVELOPMENT LDA INOVAPOTEK, PHARMACEUTICAL RESEARCH AND DEVELOPMENT LDA Organization address address: UPTEC - RUA ALFREDO ALLEN 455/461 city: PORTO postcode: 4200-135 website: www.inovapotek.com contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	PT (PORTO)	participant	36˙000.00
4	ABIEL SOCIETA A RESPONSABILITA LIMITATA ABIEL SOCIETA A RESPONSABILITA LIMITATA Organization address address: VIALE DELLE SCIENZE SN city: PALERMO postcode: 90128 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	IT (PALERMO)	participant	27˙000.00

Map

Project objective

The estimated cost of getting a new medicine to market is now in excess of $2.6 billion, with an additional $300 million (approx.) typically being directed towards post market approval research and development activities (including testing of new indications, new formulations and new dosage strengths and regimens) (Nature Reviews Drug Discovery 13, 877 (2014)). These costs have increased >145% since 2003, and reflect an increasingly complex process in which there remains a high chance of failure in the expensive later phases of development. With the aim of reducing the times and costs associated with medicine development, increasing attention has focused on the development of approaches to better predict and/or optimize the behaviour of actives and their formulations at an earlier stage of development. Recent research within the School of Pharmacy (University of Nottingham (UoN)) has focussed on the application of advanced surface analytical and biophysical tools to address this need. This proposal will build on this activity via an intersectoral researcher exchange program focussed on supporting future pharmaceutical formulations development. The principal objective of FutForm is to translate the advanced analytical approaches developed within UoN, so that they become embedded into industrial practice for the development of future pharmaceutical processes and therapies. This will be achieved through a collaborative programme of researcher secondments with three small-medium enterprise (SME) companies, each with early stage innovative technologies in areas of importance to the future pharmaceutical industry, namely; enzyme formulations for improved cell isolation (Abiel s.r.l; Italy), nanoparticle platform formulations for oral and topical drug delivery (Inovapotek, Pharmaceutical Research and Development Lda; Portugal) and hydrogel formulations for cell-delivery (Hy2Care b.v.; Netherlands).

Deliverables

List of deliverables.
Standardized SOPs for the optimized isolation of different cell types	Documents, reports	2020-01-29 12:07:31
Generation of ISO 1345 Quality Management System	Documents, reports	2020-01-29 12:07:30
Standardized protocols for the formulation of nanoparticles with defined properties	Documents, reports	2020-01-29 12:07:31
FutForm Website up and running	Websites, patent fillings, videos etc.	2020-01-29 12:07:30
Consortium agreement signed	Other	2020-01-29 12:07:30

Take a look to the deliverables list in detail: detailed list of FutForm deliverables.

Publications

List of publications.
year	authors and title	journal	last update
2018	Elaheh Jooybar, Mohammad J. Abdekhodaie, Mansour Alvi, Abbas Mousavi, Marcel Karperien, Pieter J. Dijkstra An injectable platelet lysate-hyaluronic acid hydrogel supports cellular activities and induces chondrogenesis of encapsulated mesenchymal stem cells published pages: , ISSN: 1742-7061, DOI: 10.1016/j.actbio.2018.10.031	Acta Biomaterialia	2020-01-29
2018	Simona Campora, Paola Sanjuan Alberte, Carmelo Bruno, Giulio Ghersi Isolation of Adult Rat Cardiomyocytes Using Recombinant Collagenases published pages: , ISSN: 2283-9216, DOI: 10.3303/CET1864005	CHEMICAL ENGINEERING TRANSACTIONS	2020-01-29

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The information about "FUTFORM" are provided by the European Opendata Portal: CORDIS opendata.