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STREAM SIGNED

Strategies towards Excellence in Immuno-Oncology

Total Cost €

EC-Contrib. €

Partnership

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Outcomes and
results

STREAM project word cloud

Explore the words cloud of the STREAM project. It provides you a very rough idea of what is the project "STREAM" about.

competitive expertise university 2013 summer clinical regarding bioresearch active magazine synergistic composite oncology exceptional poland strategic warsaw regional workshops centres organization provides model immunotherapy ongoing profile conducting competence indicator enrich enthusiasm cancer stream quality enlarged immuno prestigious internationally partnership muw predominant economy variables occasion ambition trans thinking medical scientific outstanding groups economic desire science dialogue announced area status joint twinning improvement standard participation immunotherapeutics character school international intend health thriving innovative enhanced visits player life society conferences breakthrough excellence human significantly merits national displays

Project "STREAM" data sheet

The following table provides information about the project.

Coordinator	WARSZAWSKI UNIWERSYTET MEDYCZNY Organization address address: UL. ZWIRKI I WIGURY 61 city: WARSZAWA postcode: 02 091 website: www.wum.edu.pl contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.
Coordinator Country	Poland [PL]
Project website	http://www.stream.wum.edu.pl/en/
Total cost	1˙190˙261 €
EC max contribution	1˙190˙261 € (100%)
Programme	1. H2020-EU.4.b. (Twinning of research institutions)
Code Call	H2020-TWINN-2015
Funding Scheme	CSA
Starting year	2016
Duration (year-month-day)	from 2016-01-01 to 2018-12-31

Partnership

Take a look of project's partnership.

#	participants	country	role	EC contrib. [€]
1	WARSZAWSKI UNIWERSYTET MEDYCZNY WARSZAWSKI UNIWERSYTET MEDYCZNY Organization address address: UL. ZWIRKI I WIGURY 61 city: WARSZAWA postcode: 02 091 website: www.wum.edu.pl contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	PL (WARSZAWA)	coordinator	640˙717.00
2	OSLO UNIVERSITETSSYKEHUS HF OSLO UNIVERSITETSSYKEHUS HF Organization address address: KIRKEVEIEN 166 TARNBYGGET city: OSLO postcode: 450 website: http://www.oslo-universitetssykehus.no contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	NO (OSLO)	participant	169˙472.00
3	THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD Organization address address: WELLINGTON SQUARE UNIVERSITY OFFICES city: OXFORD postcode: OX1 2JD website: www.ox.ac.uk contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	UK (OXFORD)	participant	140˙187.00
4	INTERNATIONAL CENTRE FOR GENETIC ENGINEERING AND BIOTECHNOLOGY INTERNATIONAL CENTRE FOR GENETIC ENGINEERING AND BIOTECHNOLOGY Organization address address: PADRICIANO 99 city: TRIESTE postcode: 34149 website: www.icgeb.org contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	IT (TRIESTE)	participant	134˙543.00
5	THE FRANCIS CRICK INSTITUTE LIMITED THE FRANCIS CRICK INSTITUTE LIMITED Organization address address: 1 MIDLAND ROAD city: LONDON postcode: NW1 1AT website: www.crick.ac.uk contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	UK (LONDON)	participant	105˙340.00

Map

Project objective

In 2013, the Science magazine announced Immunotherapy of cancer as the ‘Breakthrough of the Year’. The results of ongoing clinical studies with new cancer immunotherapeutics strongly support this enthusiasm. Following the lead of the top research groups, the Coordinator of the present proposal, Medical University of Warsaw (MUW) displays a predominant ambition of becoming a major player in the thriving area of Immuno-Oncology. MUW is one of the leading centres of competence in the Oncology field in Poland and presents a robust desire for further improvement of its excellence merits. Therefore, the main concept of the STREAM proposal is to bring together the high-level European research organizations with synergistic scientific and innovative expertise in the field of Immuno-Oncology, in order to establish an international, long-term, strategic partnership with MUW. The main model of the STREAM proposal is to foster enhanced scientific dialogue and twinning between MUW and four outstanding research centres via trans-national visits of scientific personnel, joint organization of a summer school and workshops, as well as promoting the active participation of STREAM researchers in the prestigious scientific conferences. Within the duration of the current project we intend to significantly enrich MUW’s, regional and national quality profile regarding all of the variables of Composite indicator of Research Excellence in the Immuno-Oncology area. We will also set a new standard for conducting bioresearch and innovative thinking in Poland. We expect that the scale, ambition, and innovative character of the proposed project will bring the MUW’s excellence to a new level - internationally recognized and competitive, in order to contribute to the well-being of the society and knowledge-based economy of Poland and EU. Our proposal provides an exceptional occasion to achieve real impact on human health, quality of life and economic status in the new area of enlarged Europe.

Deliverables

List of deliverables.
\"Report on organization of theoretical workshop - \"\"Adoptive immunotherapy for cancer\"\"\"	Documents, reports	2019-06-06 16:37:28
Report on management activities II	Documents, reports	2019-06-06 16:37:56
Report on participation in international research/innovation conferences - M36	Documents, reports	2019-06-06 16:37:53
Report on knowledge dissemination - M36	Documents, reports	2019-06-06 16:37:54
Report on promotional activities undertaken during theoretical workshop	Documents, reports	2019-06-06 16:37:42
Report on know-how transfer through twinning visits - M24	Documents, reports	2019-06-06 16:37:40
Report from the Steering Group Meeting II	Documents, reports	2019-06-06 16:38:09
Report from the Steering Group Meeting III	Documents, reports	2019-06-06 16:37:52
Report on know-how transfer through twinning visits - M36	Documents, reports	2019-06-06 16:37:36
Report on overall promotional activities III	Documents, reports	2019-06-06 16:37:41
Report on management activities III	Documents, reports	2019-06-06 16:38:03
Report on know-how knowledge dissemination at MUW - M24	Documents, reports	2019-06-06 16:37:38
Report on know-how knowledge dissemination at MUW - M36	Documents, reports	2019-06-06 16:37:53
Report on overall promotional activities II	Documents, reports	2019-06-06 16:37:49
\"Report on organization of hands-on workshop - \"\"Application of flow cytometry methods in Immuno-Oncology\"\"\"	Documents, reports	2019-06-06 16:37:53
Specifications of training material used for the twinning visits	Documents, reports	2019-06-06 16:37:40
Report on promotional activities undertaken during hands-on workshop	Documents, reports	2019-06-06 16:37:46
Report on publications, patents and funding support resulting from twinning visits	Documents, reports	2019-06-06 16:37:39
Report on know-how knowledge dissemination at MUW - M12	Documents, reports	2019-05-30 14:25:36
Report on knowledge dissemination - M18	Documents, reports	2019-05-30 14:25:29
Report on management activities I	Documents, reports	2019-05-30 14:25:35
\"Report on organization of international summer-school - \"\"Immuno-Oncology\"\"\"	Documents, reports	2019-05-30 14:25:38
Report on prior publications of the coordinator	Documents, reports	2019-05-30 14:25:29
Report from the Steering Group Meeting I	Documents, reports	2019-05-30 14:25:33
Report on know-how transfer through twinning visits - M12	Documents, reports	2019-05-30 14:25:33
Report on promotional activities undertaken during summer-school	Documents, reports	2019-05-30 14:25:38
Report on STREAM webpage launching	Documents, reports	2019-05-30 14:25:31
Report on overall promotional activities I	Documents, reports	2019-05-30 14:25:35
Report on participation in international research/innovation conferences - M18	Documents, reports	2019-05-30 14:25:27

Take a look to the deliverables list in detail: detailed list of STREAM deliverables.

Publications

List of publications.
year	authors and title	journal	last update
2014	Angelika Muchowicz, MaÅ‚gorzata Firczuk, Justyna Chlebowska, Dominika Nowis, Joanna Stachura, Joanna Barankiewicz, Anna Trzeciecka, Szymon KÅ‚ossowski, Ryszard Ostaszewski, RadosÅ‚aw ZagoÅ¼dÅ¼on, Jian-Xin Pu, Han-Dong Sun, Jakub Golab Adenanthin targets proteins involved in the regulation of disulphide bonds published pages: 210-216, ISSN: 0006-2952, DOI: 10.1016/j.bcp.2014.02.022	Biochemical Pharmacology 89/2	2019-06-07
2018	Binu K Sasi, Sven Turkalj, Hilal Kalkan, Fabiola Porro, Engin Bojnik, Beata Pyrzynska, Abdessamad Zerrouqi, Malgorzata Bobrowicz, Magdalena Winiarska, Valdemar Priebe, Francesco Bertoni, Larry Mansouri, Richard Rosenquist and Dimitar G Efremov SHP1 Deficiency Is Responsible for the Constitutive Activation of the BCR Pathway in GCB DLBCL published pages: 2860, ISSN: , DOI:	Blood 132 (Suppl 1)	2019-06-07
2018	Zofia Pilch, Katarzyna Tonecka, Agata Braniewska, Zuzanna Sas, Marcin Skorzynski, Louis Boon, Jakub Golab, Linde Meyaard, Tomasz P. Rygiel Antitumor Activity of TLR7 Is Potentiated by CD200R Antibody Leading to Changes in the Tumor Microenvironment published pages: 930-940, ISSN: 2326-6066, DOI: 10.1158/2326-6066.cir-17-0454	Cancer Immunology Research 6/8	2019-06-07
2016	Antoni Domagala, Malgorzata Bobrowicz, Joanna Stachura, Marta Siernicka, Piotr Mrowka, Michal Dwojak, Beata Pyrzynska, Malgorzata Firczuk and Magdalena Winiarska Lysosomal Disruption Augments Obinutuzumab-Induced Direct Cell Death published pages: 2766, ISSN: , DOI:	Blood 128/22	2019-06-07
2018	Mieszko Lachota, Marta Siernicka, Zofia Pilch, Agnieszka Graczyk-Jarzynka and Magdalena Winiarska Dasatinib Effect on NK Cells and Anti-Tumor Immunity published pages: 3004, ISSN: , DOI:	Blood 132 (Suppl 1)	2019-06-07
2015	Aleksandra Maria Dudek-PeriÄ‡, Jakub GoÅ‚Ä…b, Abhishek D Garg, Patrizia Agostinis Melanoma targeting with the loco-regional chemotherapeutic, Melphalan: From cell death to immunotherapeutic efficacy published pages: e1054600, ISSN: 2162-402X, DOI: 10.1080/2162402x.2015.1054600	OncoImmunology 4/12	2019-06-07
2016	Malgorzata Bobrowicz, Joanna Stachura, Michal Dwojak, Antoni Domagala, Beata Pyrzynska, Elise Berthel, Nicole Dalla Venezia, Marta Siernicka, Malgorzata Firczuk and Magdalena Winiarska HDAC6 Inhibition Increases Translation of CD20 mRNA and Potentiates the Efficacy of Anti-CD20 Immunotherapy published pages: 1586, ISSN: , DOI:	Blood 128/22	2019-06-07
2018	Krzysztof SzczaÅ‚uba, Joanna J. Chmielewska, Olga Sokolowska, MaÅ‚gorzata Rydzanicz, Krystyna SzymaÅ„ska, Wojciech Feleszko, PaweÅ‚ WÅ‚odarski, Anna Biernacka, Victor Murcia Pienkowski, Anna Walczak, ElÅ¼bieta BargeÅ‚, Katarzyna KrÃ³lewczyk, Agata Nowacka, Piotr StawiÅ„ski, Dominika Nowis, Magdalena Dziembowska, RafaÅ‚ PÅ‚oski Neurodevelopmental phenotype caused by a de novo PTPN4 single nucleotide variant disrupting protein localization in neuronal dendritic spines published pages: 581-585, ISSN: 0009-9163, DOI: 10.1111/cge.13450	Clinical Genetics 94/6	2019-06-07
2018	Marzena Mazur, Agnieszka Bartoszewicz, Barbara Dymek, Magdalena Salamon, Gleb Andryianau, MichaÅ‚ Kowalski, Sylwia Olejniczak, Krzysztof Matyszewski, ElÅ¼bieta Pluta, BartÅ‚omiej Borek, Filip Stefaniak, Agnieszka Zagozdzon, Marcin Mazurkiewicz, Robert Koralewski, Wojciech Czestkowski, MichaÅ‚ Piotrowicz, Piotr Niedziejko, Mariusz M. Gruza, Karolina Dzwonek, Adam Golebiowski, Jakub Golab, Jacek Olczak Discovery of selective, orally bioavailable inhibitor of mouse chitotriosidase published pages: 310-314, ISSN: 0960-894X, DOI: 10.1016/j.bmcl.2017.12.047	Bioorganic & Medicinal Chemistry Letters 28/3	2019-06-07
2018	A. Bujnowska, M. Michon, P. Konopelski, E. Hryniewiecka, A. Jalbrzykowska, A. Perkowska-Ptasinska, T. Cieciura, R. Zagozdzon, L. Paczek, M. Ciszek Outcomes of Prolonged Treatment With Intravenous Immunoglobulin Infusions for Acute Antibody-mediated Rejection in Kidney Transplant Recipients published pages: 1720-1725, ISSN: 0041-1345, DOI: 10.1016/j.transproceed.2018.02.110	Transplantation Proceedings 50/6	2019-06-07
2017	Valeria Guglielmi, Dominika Nowis, Martina Tinelli, Manuela Malatesta, Laura Paoli, Matteo Marini, Paolo Manganotti, Radoslaw Sadowski, Grzegorz M. Wilczynski, Vittorio Meneghini, Giuliano Tomelleri, Gaetano Vattemi Bortezomib-Induced Muscle Toxicity in Multiple Myeloma published pages: 620-630, ISSN: 0022-3069, DOI: 10.1093/jnen/nlx043	Journal of Neuropathology & Experimental Neurology 76/7	2019-06-07
2015	Angelika Muchowicz, MaÅ‚gorzata Firczuk, MaÅ‚gorzata Wachowska, Marek Kujawa, Ewa Jankowska-Steifer, Magdalena Gabrysiak, Zofia Pilch, Szymon KÅ‚ossowski, Ryszard Ostaszewski, Jakub Golab SK053 triggers tumor cells apoptosis by oxidative stress-mediated endoplasmic reticulum stress published pages: 418-427, ISSN: 0006-2952, DOI: 10.1016/j.bcp.2014.12.019	Biochemical Pharmacology 93/4	2019-06-07
2017	Elina Timosenko, Andreas V Hadjinicolaou, Vincenzo Cerundolo Modulation of cancer-specific immune responses by amino acid degrading enzymes published pages: 83-97, ISSN: 1750-743X, DOI: 10.2217/imt-2016-0118	Immunotherapy 9/1	2019-06-06
2016	Joanna Stachura, Malgorzata Wachowska, Witold W. Kilarski, Esra GÃ¼Ã§, Jakub Golab, Angelika Muchowicz The dual role of tumor lymphatic vessels in dissemination of metastases and immune response development published pages: e1182278, ISSN: 2162-402X, DOI: 10.1080/2162402X.2016.1182278	OncoImmunology 5/7	2019-06-06
2017	Agnieszka Graczyk-Jarzynka, Radoslaw Zagozdzon, Angelika Muchowicz, Marta Siernicka, Malgorzata Firczuk, Przemyslaw Juszczynski New insights into redox homeostasis as a therapeutic target in B-cell malignancies published pages: 1, ISSN: 1065-6251, DOI: 10.1097/MOH.0000000000000351	Current Opinion in Hematology 24/4	2019-06-06
2016	Elina Timosenko, Hemza Ghadbane, Jonathan D. Silk, Dawn Shepherd, Uzi Gileadi, Lauren J. Howson, Robert Laynes, Qi Zhao, Robert L. Strausberg, Lars R. Olsen, Stephen Taylor, Francesca M. Buffa, Richard Boyd, Vincenzo Cerundolo Nutritional Stress Induced by Tryptophan-Degrading Enzymes Results in ATF4-Dependent Reprogramming of the Amino Acid Transporter Profile in Tumor Cells published pages: 6193-6204, ISSN: 0008-5472, DOI: 10.1158/0008-5472.CAN-15-3502	Cancer Research 76/21	2019-06-06
2016	M SÅ‚abicki, K S Lee, A Jethwa, L Sellner, F Sacco, T Walther, J HÃ¼llein, S Dietrich, B Wu, D B Lipka, C C Oakes, S Mamidi, B PyrzyÅ„ska, M Winiarska, M OleÅ›, M Seifert, C Plass, M Kirschfink, M Boettcher, J GoÅ‚Ä…b, W Huber, S FrÃ¶hling, T Zenz Dissection of CD20 regulation in lymphoma using RNAi published pages: 2409-2412, ISSN: 0887-6924, DOI: 10.1038/leu.2016.230	Leukemia 30/12	2019-06-07
2017	Ole-Jacob Norum, Ane Sofie Viset Fremstedal, Anette Weyergang, Jakub Golab, Kristian Berg Photochemical delivery of bleomycin induces T-cell activation of importance for curative effect and systemic anti-tumor immunity published pages: 120-127, ISSN: 0168-3659, DOI: 10.1016/j.jconrel.2017.10.015	Journal of Controlled Release 268	2019-05-23
2018	Antoni Domagala, Klaudyna Fidyt, Malgorzata Bobrowicz, Joanna Stachura, Kacper Szczygiel, Malgorzata Firczuk Typical and Atypical Inducers of Lysosomal Cell Death: A Promising Anticancer Strategy published pages: 2256, ISSN: 1422-0067, DOI: 10.3390/ijms19082256	International Journal of Molecular Sciences 19/8	2019-05-23
2017	Ole-Jacob Norum, Ane Sofie Viset Fremstedal, Anette Weyergang, Jakub Golab, Kristian Berg Photochemical delivery of bleomycin induces T-cell activation of importance for curative effect and systemic anti-tumor immunity published pages: 120-127, ISSN: 0168-3659, DOI: 10.1016/j.jconrel.2017.10.015	Journal of Controlled Release 268	2019-06-07
2018	Natalia Krata, RadosÅ‚aw ZagoÅ¼dÅ¼on, Bartosz Foroncewicz, Krzysztof Mucha Oxidative Stress in Kidney Diseases: The Cause or the Consequence? published pages: 211-220, ISSN: 0004-069X, DOI: 10.1007/s00005-017-0496-0	Archivum Immunologiae et Therapiae Experimentalis 66/3	2019-05-23
2018	Antoni Domagala, Joanna Stachura, Magdalena Gabrysiak, Angelika Muchowicz, Radoslaw Zagozdzon, Jakub Golab, Malgorzata Firczuk Inhibition of autophagy sensitizes cancer cells to Photofrin-based photodynamic therapy published pages: 210, ISSN: 1471-2407, DOI: 10.1186/s12885-018-4126-y	BMC Cancer 18/1	2019-05-23
2015	Kamil Bojarczuk, Malgorzata Bobrowicz, Michal Dwojak, Nina Miazek, Piotr Zapala, Anders Bunes, Marta Siernicka, Maria Rozanska, Magdalena Winiarska B-cell receptor signaling in the pathogenesis of lymphoid malignancies published pages: 255-265, ISSN: 1079-9796, DOI: 10.1016/j.bcmd.2015.06.016	Blood Cells, Molecules, and Diseases 55/3	2019-06-07
2016	Luca Laurenti, Francesco Autore, Idanna Innocenti, Giovanni Dâ€™Arena, Marta Coscia, Patrizia Mondello, Patrizia Chiusolo, Silvia Bellesi, Dimitar G. Efremov, Simona Sica, Francesca Romana Mauro Autoimmune hemolytic anemia during bendamustine plus rituximab treatment in CLL patients: multicenter experience published pages: 2429-2431, ISSN: 1042-8194, DOI: 10.3109/10428194.2015.1137293	Leukemia & Lymphoma 57/10	2019-06-07
2017	G Lohmann, E Vasyutina, J Bloehdorn, N Reinart, J I Schneider, V Babu, G Knittel, G Crispatzu, P Mayer, C Prinz, J K Muenzner, B Biersack, D G Efremov, L Chessa, C D Herling, S Stilgenbauer, M Hallek, R Schobert, H C Reinhardt, B Schumacher, M Herling Targeting transcription-coupled nucleotide excision repair overcomes resistance in chronic lymphocytic leukemia published pages: 1177-1186, ISSN: 0887-6924, DOI: 10.1038/leu.2016.294	Leukemia 31/5	2019-06-07
2017	Urszula Lechowicz, Tomasz Gambin, Agnieszka Pollak, Anna Podgorska, Piotr Stawinski, Andre Franke, Britt-Sabina Petersen, Malgorzata Firczuk, Monika Oldak, Henryk Skarzynski, Rafal Ploski Iterative Sequencing and Variant Screening (ISVS) as a novel pathogenic mutations search strategy - application for TMPRSS3 mutations screen published pages: , ISSN: 2045-2322, DOI: 10.1038/s41598-017-02315-w	Scientific Reports 7/1	2019-04-17
2018	Marzena Mazur, Jacek Olczak, Sylwia Olejniczak, Robert Koralewski, Wojciech Czestkowski, Anna Jedrzejczak, Jakub Golab, Karolina Dzwonek, Barbara Dymek, Piotr L. Sklepkiewicz, Agnieszka Zagozdzon, Tom Noonan, Keyvan Mahboubi, Bruce Conway, Ryan Sheeler, Paul Beckett, William M. Hungerford, Alberto Podjarny, Andre Mitschler, Alexandra Cousido-Siah, Firas Fadel, Adam Golebiowski Targeting Acidic Mammalian chitinase Is Effective in Animal Model of Asthma published pages: 695-710, ISSN: 0022-2623, DOI: 10.1021/acs.jmedchem.7b01051	Journal of Medicinal Chemistry 61/3	2019-06-07
2017	Angelika Muchowicz, Malgorzata Wachowska, Joanna Stachura, Katarzyna Tonecka, Magdalena Gabrysiak, Dominika WoÅ‚osz, Zofia Pilch, Witold W. Kilarski, Louis Boon, Tomasz J. Klaus, Jakub Golab Inhibition of lymphangiogenesis impairs antitumour effects of photodynamic therapy and checkpoint inhibitors in mice published pages: 19-27, ISSN: 0959-8049, DOI: 10.1016/j.ejca.2017.06.004	European Journal of Cancer 83	2019-06-07
2018	Beata Pyrzynska, Michal Dwojak, Abdessamad Zerrouqi, Giulia Morlino, Piotr Zapala, Nina Miazek, Agnieszka Zagozdzon, Kamil Bojarczuk, Malgorzata Bobrowicz, Marta Siernicka, Marcin M. Machnicki, Stefania Gobessi, Joanna Barankiewicz, Ewa Lech-Maranda, Dimitar G. Efremov, Przemyslaw Juszczynski, Dinis Calado, Jakub Golab, Magdalena Winiarska FOXO1 promotes resistance of non-Hodgkin lymphomas to anti-CD20-based therapy published pages: e1423183, ISSN: 2162-402X, DOI: 10.1080/2162402X.2017.1423183	OncoImmunology 7/5	2019-04-17
2016	Anna Trzeciecka, Szymon Klossowski, Malgorzata Bajor, Radoslaw Zagozdzon, Pawel Gaj, Angelika Muchowicz, Agata Malinowska, Anna Czerwoniec, Joanna Barankiewicz, Antoni Domagala, Justyna Chlebowska, Monika Prochorec-Sobieszek, Magdalena Winiarska, Ryszard Ostaszewski, Iwonna Gwizdalska, Jakub Golab, Dominika Nowis, Malgorzata Firczuk Dimeric peroxiredoxins are druggable targets in human Burkitt lymphoma published pages: 1717-1731, ISSN: 1949-2553, DOI: 10.18632/oncotarget.6435	Oncotarget 7/2	2019-04-17
2018	Marcin Waligora, Malgorzata M. Bala, Magdalena Koperny, Mateusz T. Wasylewski, Karolina Strzebonska, RafaÅ‚ R. Jaeschke, Agnieszka Wozniak, Jan Piasecki, Agnieszka Sliwka, Jerzy W. Mitus, Maciej Polak, Dominika Nowis, Dean Fergusson, Jonathan Kimmelman Risk and surrogate benefit for pediatric Phase I trials in oncology: A systematic review with meta-analysis published pages: e1002505, ISSN: 1549-1676, DOI: 10.1371/journal.pmed.1002505	PLOS Medicine 15/2	2019-04-17
2017	Magdalena Winiarska, Dominika Nowis, Malgorzata Firczuk, Agnieszka Zagozdzon, Magdalena Gabrysiak, Radoslaw Sadowski, Joanna Barankiewicz, Michal Dwojak, Jakub Golab Selection of an optimal promoter for gene transfer in normal B cells published pages: 3041-3048, ISSN: 1791-2997, DOI: 10.3892/mmr.2017.6974	Molecular Medicine Reports 16/3	2019-04-17
2017	Malgorzata Bobrowicz, Michal Dwojak, Beata Pyrzynska, Joanna Stachura, Angelika Muchowicz, Elise Berthel, Nicole Dalla Venezia, Mieszko Kozikowski, Marta Siernicka, Nina Miazek, Piotr Zapala, Antoni Domagala, Kamil Bojarczuk, Agata Malenda, Joanna Barankiewicz, Agnieszka Graczyk-Jarzynka, Agnieszka Zagozdzon, Magdalena Gabrysiak, Jean-Jacques Diaz, Marta Karp, Ewa Lech-Maranda, Malgorzata Firczuk, Krzysztof Giannopoulos, Dimitar G. Efremov, Luca Laurenti, Dunja Baatout, Lukas Frenzel, Agata Malinowska, Mikolaj Slabicki, Thorsten Zenz, Abdessamad Zerrouqi, Jakub Golab, Magdalena Winiarska HDAC6 inhibition up-regulates CD20 levels and increases the efficacy of anti-CD20 monoclonal antibodies published pages: blood-2016-08-73, ISSN: 0006-4971, DOI: 10.1182/blood-2016-08-736066	Blood 130(14):1628-1638	2019-04-17
2018	Marzena Mazur, Jacek Olczak, Sylwia Olejniczak, Robert Koralewski, Wojciech Czestkowski, Anna Jedrzejczak, Jakub Golab, Karolina Dzwonek, Barbara Dymek, Piotr L. Sklepkiewicz, Agnieszka Zagozdzon, Tom Noonan, Keyvan Mahboubi, Bruce Conway, Ryan Sheeler, Paul Beckett, William M. Hungerford, Alberto Podjarny, Andre Mitschler, Alexandra Cousido-Siah, Firas Fadel, Adam Golebiowski Targeting Acidic Mammalian chitinase Is Effective in Animal Model of Asthma published pages: 695-710, ISSN: 0022-2623, DOI: 10.1021/acs.jmedchem.7b01051	Journal of Medicinal Chemistry 61/3	2019-04-17
2018	Anna Burdzinska, Bartosz Dybowski, Weronika Zarychta-WiÅ›niewska, Agnieszka Kulesza, Marta Butrym, Radoslaw Zagozdzon, Agnieszka Graczyk-Jarzynka, Piotr Radziszewski, Zdzislaw Gajewski, Leszek Paczek Intraurethral co-transplantation of bone marrow mesenchymal stem cells and muscle-derived cells improves the urethral closure published pages: 239, ISSN: 1757-6512, DOI: 10.1186/s13287-018-0990-2	Stem Cell Research & Therapy 9/1	2019-04-17
2018	Zofia Pilch, Katarzyna Tonecka, Agata Braniewska, Zuzanna Sas, Marcin Skorzynski, Louis Boon, Jakub Golab, Linde Meyaard, Tomasz P. Rygiel Antitumor Activity of TLR7 Is Potentiated by CD200R Antibody Leading to Changes in the Tumor Microenvironment published pages: 930-940, ISSN: 2326-6066, DOI: 10.1158/2326-6066.CIR-17-0454	Cancer Immunology Research 6/8	2019-04-17
2017	Angelika Muchowicz, Malgorzata Wachowska, Joanna Stachura, Katarzyna Tonecka, Magdalena Gabrysiak, Dominika WoÅ‚osz, Zofia Pilch, Witold W. Kilarski, Louis Boon, Tomasz J. Klaus, Jakub Golab Inhibition of lymphangiogenesis impairs antitumour effects of photodynamic therapy and checkpoint inhibitors in mice published pages: 19-27, ISSN: 0959-8049, DOI: 10.1016/j.ejca.2017.06.004	European Journal of Cancer 83	2019-04-17
2018	Agata O. Zych, Malgorzata Bajor, Radoslaw Zagozdzon Application of Genome Editing Techniques in Immunology published pages: 289-298, ISSN: 0004-069X, DOI: 10.1007/s00005-018-0504-z	Archivum Immunologiae et Therapiae Experimentalis 66/4	2019-04-17
2017	Weronika Zarychta-WiÅ›niewska, Anna Burdzinska, RadosÅ‚aw Zagozdzon, Bartosz Dybowski, Marta Butrym, ZdzisÅ‚aw Gajewski, Leszek Paczek In vivo imaging system for explants analysisâ€”A new approach for assessment of cell transplantation effects in large animal models published pages: e0184588, ISSN: 1932-6203, DOI: 10.1371/journal.pone.0184588	PLOS ONE 12/9	2019-04-17
2017	Seweryn Mroczek, Justyna Chlebowska, Tomasz M. KuliÅ„ski, Olga Gewartowska, Jakub Gruchota, Dominik Cysewski, Vladyslava Liudkovska, Ewa Borsuk, Dominika Nowis, Andrzej Dziembowski The non-canonical poly(A) polymerase FAM46C acts as an onco-suppressor in multiple myeloma published pages: 619, ISSN: 2041-1723, DOI: 10.1038/s41467-017-00578-5	Nature Communications 8/1	2019-04-17
2018	Justyna Chlebowska-Tuz, Olga Sokolowska, Pawel Gaj, Michal Lazniewski, Malgorzata Firczuk, Karolina Borowiec, Hanna Sas-Nowosielska, Malgorzata Bajor, Agata Malinowska, Angelika Muchowicz, Kavita Ramji, Piotr Stawinski, Mateusz Sobczak, Zofia Pilch, Anna Rodziewicz-Lurzynska, Malgorzata Zajac, Krzysztof Giannopoulos, Przemyslaw Juszczynski, Grzegorz W. Basak, Dariusz Plewczynski, Rafal Ploski, Jakub Golab, Dominika Nowis Inhibition of protein disulfide isomerase induces differentiation of acute myeloid leukemia cells published pages: 1843-1852, ISSN: 0390-6078, DOI: 10.3324/haematol.2018.190231	Haematologica 103/11	2019-04-17
2016	MAGDALENA GABRYSIAK, MALGORZATA WACHOWSKA, JOANNA BARANKIEWICZ, ZOFIA PILCH, ANNA RATAJSKA, EWA SKRZYPEK, MAGDALENA WINIARSKA, ANTONI DOMAGALA, TOMASZ P. RYGIEL, ALICJA JOZKOWICZ, LOUIS BOON, JAKUB GOLAB, MALGORZATA FIRCZUK Low dose of GRP78-targeting subtilase cytotoxin improves the efficacy of photodynamic therapy in vivo published pages: 3151-3158, ISSN: 1021-335X, DOI: 10.3892/or.2016.4723	Oncology Reports 35/6	2019-04-17
2018	Vincent Yi Sheng Oei, Marta Siernicka, Agnieszka Graczyk-Jarzynka, Hanna Julie Hoel, Weiwen Yang, Daniel Palacios, Hilde AlmÃ¥sbak, Malgorzata Bajor, Dennis Clement, Ludwig Brandt, BjÃ¶rn Ã–nfelt, Jodie Goodridge, Magdalena Winiarska, Radoslaw Zagozdzon, Johanna Olweus, Jon-Amund Kyte, Karl-Johan Malmberg Intrinsic Functional Potential of NK-Cell Subsets Constrains Retargeting Driven by Chimeric Antigen Receptors published pages: 467-480, ISSN: 2326-6066, DOI: 10.1158/2326-6066.CIR-17-0207	Cancer Immunology Research 6/4	2019-04-17
2017	Anna Burdzinska, Bartosz Dybowski, Weronika Zarychta-Wisniewska, Agnieszka Kulesza, Radoslaw Zagozdzon, Zdzislaw Gajewski, Leszek Paczek The Anatomy of Caprine Female Urethra and Characteristics of Muscle and Bone Marrow Derived Caprine Cells for Autologous Cell Therapy Testing published pages: 577-588, ISSN: 1932-8486, DOI: 10.1002/ar.23498	The Anatomical Record 300/3	2019-04-17
2016	Anna Polak, PrzemysÅ‚aw Kiliszek, Tomasz Sewastianik, Maciej SzydÅ‚owski, Ewa JabÅ‚oÅ„ska, Emilia BiaÅ‚opiotrowicz, Patryk GÃ³rniak, Sergiusz Markowicz, Eliza Nowak, Monika A. Grygorowicz, Monika Prochorec-Sobieszek, Dominika Nowis, Jakub GoÅ‚Ä…b, Sebastian Giebel, Ewa Lech-MaraÅ„da, Krzysztof Warzocha, PrzemysÅ‚aw JuszczyÅ„ski MEK Inhibition Sensitizes Precursor B-Cell Acute Lymphoblastic Leukemia (B-ALL) Cells to Dexamethasone through Modulation of mTOR Activity and Stimulation of Autophagy published pages: e0155893, ISSN: 1932-6203, DOI: 10.1371/journal.pone.0155893	PLOS ONE 11/5	2019-04-17
2016	Anna Polak, PrzemysÅ‚aw Kiliszek, Tomasz Sewastianik, Maciej SzydÅ‚owski, Ewa JabÅ‚oÅ„ska, Emilia BiaÅ‚opiotrowicz, Patryk GÃ³rniak, Sergiusz Markowicz, Eliza Nowak, Monika A. Grygorowicz, Monika Prochorec-Sobieszek, Dominika Nowis, Jakub GoÅ‚Ä…b, Sebastian Giebel, Ewa Lech-MaraÅ„da, Krzysztof Warzocha, PrzemysÅ‚aw JuszczyÅ„ski MEK Inhibition Sensitizes Precursor B-Cell Acute Lymphoblastic Leukemia (B-ALL) Cells to Dexamethasone through Modulation of mTOR Activity and Stimulation of Autophagy published pages: e0155893, ISSN: 1932-6203, DOI: 10.1371/journal.pone.0155893	PLOS ONE 11/5	2019-06-14
2016	Andreas T. BjÃ¶rklund, Trevor Clancy, Jodie P. Goodridge, Vivien BÃ©ziat, Marie Schaffer, Eivind Hovig, Hans-Gustaf Ljunggren, Per T. Ljungman, Karl-Johan Malmberg Naive Donor NK Cell Repertoires Associated with Less Leukemia Relapse after Allogeneic Hematopoietic Stem Cell Transplantation published pages: 1400-1411, ISSN: 0022-1767, DOI: 10.4049/jimmunol.1501434	The Journal of Immunology 196/3	2019-06-14
2016	P. J. Brown, D. M. Gascoyne, L. Lyne, H. Spearman, S. L. Felce, N. McFadden, P. Chakravarty, S. Barrans, S. Lynham, D. P. Calado, M. Ward, A. H. Banham N-terminally truncated FOXP1 protein expression and alternate internal FOXP1 promoter usage in normal and malignant B cells published pages: 861-871, ISSN: 0390-6078, DOI: 10.3324/haematol.2016.142141	Haematologica 101/7	2019-06-14
2017	Malgorzata Bobrowicz, Michal Dwojak, Beata Pyrzynska, Joanna Stachura, Angelika Muchowicz, Elise Berthel, Nicole Dalla Venezia, Mieszko Kozikowski, Marta Siernicka, Nina Miazek, Piotr Zapala, Antoni Domagala, Kamil Bojarczuk, Agata Malenda, Joanna Barankiewicz, Agnieszka Graczyk-Jarzynka, Agnieszka Zagozdzon, Magdalena Gabrysiak, Jean-Jacques Diaz, Marta Karp, Ewa Lech-Maranda, Malgorzata Firczuk, Krzysztof Giannopoulos, Dimitar G. Efremov, Luca Laurenti, Dunja Baatout, Lukas Frenzel, Agata Malinowska, Mikolaj Slabicki, Thorsten Zenz, Abdessamad Zerrouqi, Jakub Golab, Magdalena Winiarska HDAC6 inhibition up-regulates CD20 levels and increases the efficacy of anti-CD20 monoclonal antibodies published pages: blood-2016-08-73, ISSN: 0006-4971, DOI: 10.1182/blood-2016-08-736066	Blood 130(14):1628-1638	2019-06-14
2016	Maryaline Coffre, David Benhamou, David RieÃŸ, Lili Blumenberg, Valentina Snetkova, Marcus J. Hines, Tirtha Chakraborty, Sofia Bajwa, Kari Jensen, Mark M.W. Chong, Lelise Getu, Gregg J. Silverman, Robert Blelloch, Dan R. Littman, Dinis Calado, Doron Melamed, Jane A. Skok, Klaus Rajewsky, Sergei B. Koralov miRNAs Are Essential for the Regulation of the PI3K/AKT/FOXO Pathway and Receptor Editing during BÂ Cell Maturation published pages: 2271-2285, ISSN: 2211-1247, DOI: 10.1016/j.celrep.2016.11.006	Cell Reports 17/9	2019-06-14
2016	Vanessa Landtwing, Ana Raykova, Gaetana Pezzino, Vivien BÃ©ziat, Emanuela Marcenaro, Claudine Graf, Alessandro Moretta, Riccarda Capaul, Andrea Zbinden, Guido Ferlazzo, Karl-Johan Malmberg, Obinna Chijioke, Christian MÃ¼nz Cognate HLA absence in trans diminishes human NK cell education published pages: 3772-3782, ISSN: 0021-9738, DOI: 10.1172/JCI86923	Journal of Clinical Investigation 126/10	2019-06-14
2016	Nadia Mensali, Fan Ying, Vincent Oei Yi Sheng, Weiwen Yang, Even Walseng, Shraddha Kumari, Lars-Egil Fallang, Arne Kolstad, Wolfgang Uckert, Karl Johan Malmberg, SÃ©bastien WÃ¤lchli, Johanna Olweus Targeting B-cell neoplasia with T-cell receptors recognizing a CD20-derived peptide on patient-specific HLA published pages: e1138199, ISSN: 2162-402X, DOI: 10.1080/2162402X.2016.1138199	OncoImmunology 5/5	2019-06-14
2016	K. Bojarczuk, B. K. Sasi, S. Gobessi, I. Innocenti, G. Pozzato, L. Laurenti, D. G. Efremov BCR signaling inhibitors differ in their ability to overcome Mcl-1-mediated resistance of CLL B cells to ABT-199 published pages: 3192-3201, ISSN: 0006-4971, DOI: 10.1182/blood-2015-10-675009	Blood 127/25	2019-04-17
2016	D. G. Efremov IL-4 regulates B-cell receptor signaling in CLL published pages: 468-469, ISSN: 0006-4971, DOI: 10.1182/blood-2016-06-719872	Blood 128/4	2019-06-14
2016	Luca Laurenti, Idanna Innocenti, Francecso Autore, Simona Sica, Dimitar Efremov New developments in the management of chronic lymphocytic leukemia: role of ofatumumab published pages: 421, ISSN: 1178-6930, DOI: 10.2147/OTT.S72845	OncoTargets and Therapy	2019-06-14
2017	Anna Burdzinska, Bartosz Dybowski, Weronika Zarychta-Wisniewska, Agnieszka Kulesza, Radoslaw Zagozdzon, Zdzislaw Gajewski, Leszek Paczek The Anatomy of Caprine Female Urethra and Characteristics of Muscle and Bone Marrow Derived Caprine Cells for Autologous Cell Therapy Testing published pages: 577-588, ISSN: 1932-8486, DOI: 10.1002/ar.23498	The Anatomical Record 300/3	2019-06-14
2016	K. Bojarczuk, B. K. Sasi, S. Gobessi, I. Innocenti, G. Pozzato, L. Laurenti, D. G. Efremov BCR signaling inhibitors differ in their ability to overcome Mcl-1-mediated resistance of CLL B cells to ABT-199 published pages: 3192-3201, ISSN: 0006-4971, DOI: 10.1182/blood-2015-10-675009	Blood 127/25	2019-06-14
2016	MAGDALENA GABRYSIAK, MALGORZATA WACHOWSKA, JOANNA BARANKIEWICZ, ZOFIA PILCH, ANNA RATAJSKA, EWA SKRZYPEK, MAGDALENA WINIARSKA, ANTONI DOMAGALA, TOMASZ P. RYGIEL, ALICJA JOZKOWICZ, LOUIS BOON, JAKUB GOLAB, MALGORZATA FIRCZUK Low dose of GRP78-targeting subtilase cytotoxin improves the efficacy of photodynamic therapy in vivo published pages: 3151-3158, ISSN: 1021-335X, DOI: 10.3892/or.2016.4723	Oncology Reports 35/6	2019-06-14
2018	Beata Pyrzynska, Michal Dwojak, Abdessamad Zerrouqi, Giulia Morlino, Piotr Zapala, Nina Miazek, Agnieszka Zagozdzon, Kamil Bojarczuk, Malgorzata Bobrowicz, Marta Siernicka, Marcin M. Machnicki, Stefania Gobessi, Joanna Barankiewicz, Ewa Lech-Maranda, Dimitar G. Efremov, Przemyslaw Juszczynski, Dinis Calado, Jakub Golab, Magdalena Winiarska FOXO1 promotes resistance of non-Hodgkin lymphomas to anti-CD20-based therapy published pages: e1423183, ISSN: 2162-402X, DOI: 10.1080/2162402X.2017.1423183	OncoImmunology 7/5	2019-06-14
2017	Urszula Lechowicz, Tomasz Gambin, Agnieszka Pollak, Anna Podgorska, Piotr Stawinski, Andre Franke, Britt-Sabina Petersen, Malgorzata Firczuk, Monika Oldak, Henryk Skarzynski, Rafal Ploski Iterative Sequencing and Variant Screening (ISVS) as a novel pathogenic mutations search strategy - application for TMPRSS3 mutations screen published pages: , ISSN: 2045-2322, DOI: 10.1038/s41598-017-02315-w	Scientific Reports 7/1	2019-06-14
2016	LisaÂ L. Liu, Johannes Landskron, EivindÂ H. Ask, Monika Enqvist, Ebba Sohlberg, JamesÂ A. Traherne, Quirin Hammer, JodieÂ P. Goodridge, Stella Larsson, Jyothi Jayaraman, VincentÂ Y.S. Oei, Marie Schaffer, Kjetil TaskÃ©n, Hans-Gustaf Ljunggren, Chiara Romagnani, John Trowsdale, Karl-Johan Malmberg, Vivien BÃ©ziat Critical Role of CD2 Co-stimulation in Adaptive Natural Killer Cell Responses Revealed in NKG2C-Deficient Humans published pages: 1088-1099, ISSN: 2211-1247, DOI: 10.1016/j.celrep.2016.04.005	Cell Reports 15/5	2019-06-14
2016	D. G. Efremov FOXO discriminates tonic from chronic in DLBCL published pages: 669-670, ISSN: 0006-4971, DOI: 10.1182/blood-2015-12-683441	Blood 127/6	2019-06-14

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The information about "STREAM" are provided by the European Opendata Portal: CORDIS opendata.