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denovoSkin SIGNED

Personalized, bio-engineered skin grafts for the permanent treatment of skin defects

Total Cost €

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EC-Contrib. €

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Partnership

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 denovoSkin project word cloud

Explore the words cloud of the denovoSkin project. It provides you a very rough idea of what is the project "denovoSkin" about.

rehabilitation    donor    hence    leads    clinical    impair    invested    classified    interventions    surgical    global    epidermal    ema    biopsy    graft    painful    assuring    optimal    homecare    issue    excision    medical    movement    leaves    considerable    worldwide    sme    fits    considerably    burns    avoids    off    transplantation    scarrring    standard    drug    orphan    autologous    shortage    17    granted    financial    automate    5m    structure    significantly    fda    human    performance    scars    risking    dermo    engineered    surgeries    solving    burden    psychosocial    16    fast    follow    atmp    defects    projected    savings    quantities    site    minimal    corrective    swissmedic    world    wounds    logistics    treatment    bio    starting    suffer    de    stamp    skin    entire    personalized    market    last    permanent    50m    sound    care    intervention    disfiguring    sized    reduce    patented    restore    life    trade    outstanding    health    deployment    debilitating    patients    quality    economic    plan    designation    autografting    investment    instrument    denovoskin    intense    57m    therapy    patient    every    function   

Project "denovoSkin" data sheet

The following table provides information about the project.

Coordinator
CUTISS AG 

Organization address
address: WEINBERGSTRASSE 35 WYSS TRANSLATIONAL CENTER ZURICH DENOVOS
city: ZURICH
postcode: 8006
website: n.a.

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Switzerland [CH]
 Project website https://cutiss.swiss/
 Total cost 3˙571˙237 €
 EC max contribution 2˙499˙866 € (70%)
 Programme 1. H2020-EU.3. (PRIORITY 'Societal challenges)
2. H2020-EU.2.3. (INDUSTRIAL LEADERSHIP - Innovation In SMEs)
3. H2020-EU.2.1. (INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies)
 Code Call H2020-SMEInst-2018-2020-2
 Funding Scheme SME-2
 Starting year 2018
 Duration (year-month-day) from 2018-10-01   to  2020-09-30

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    CUTISS AG CH (ZURICH) coordinator 2˙499˙866.00

Map

 Project objective

Every year in the world, more than 50M patients suffer from skin defects (e.g. burns, excision, etc.) and need surgical intervention to restore skin function. Standard of care, skin autografting, very often leaves these patients with scars. Scars are permanent and disfiguring, and can also be painful and highly debilitating. Indeed, they may also impair movement and growth, and require several follow-up surgeries, intense homecare and psychosocial rehabilitation. Hence, scars significantly affect patient’s quality of life, along with the economic burden for the health-care system. Furthermore, in the case of large wounds, donor site shortage represents a real clinical issue.

denovoSkin™ is a patented, personalized, autologous bio-engineered human skin graft classified as Advanced Therapy Medical Product (ATMP). It is engineered in large quantities starting-off from a stamp-sized skin biopsy of the patient, thus solving the donor site shortage issue. Moreover, because of its dermo-epidermal structure, denovoSkin™ leads to minimal scarrring after transplantation. Its outstanding performance could considerably reduce or even avoids further corrective interventions, allowing for considerable savings in terms of costs. denovoSkin™ is also granted with Orphan Drug Designation for the treatment of burns by Swissmedic, EMA and FDA.

So far, more than €17.5M have been invested over the last 16 years of research into the development and the clinical testing of denovoSkin™. To have denovoSkin™ fully projected at a European and global level we need a further investment of €3.57M to automate its production, de-risking the entire denovoSkin™ project by assuring a real delivery to patients worldwide while providing optimal logistics and quality of product.

The proposed work in Phase 2 of the SME instrument fits into our overall plan to reach the market by contributing the financial resources needed to plan a fast sound wider deployment of denovoSkin™ and its market uptake.

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The information about "DENOVOSKIN" are provided by the European Opendata Portal: CORDIS opendata.

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