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GSYNCOR SIGNED

Graphene-syncronized coherent Raman scattering laser and microscope

Total Cost €

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EC-Contrib. €

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Partnership

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 GSYNCOR project word cloud

Explore the words cloud of the GSYNCOR project. It provides you a very rough idea of what is the project "GSYNCOR" about.

biomedical    scattering    illuminating    technique    wavelength    ultrashort    operation    therapeutic    time    handling    costly    pulsed    measuring    label    imaging    patient    gsyncor    molecules    reducing    visual    vivo    simplify    quantitative    qualitative    histopathology    generating    standard    followed    depending    free    composition    illuminated    subjective    complexity    image    proven    orders    synchronized    prevented    invasive    prohibiting    decisions    discriminate    doctors    locked    judgement    tumour    diagnostics    excisions    microscopy    sensitivity    synchronize    doctor    grade    optical    ing    clinical    capability    complete    slow    molecular    specialized    signal    weak    ultrafast    diseased    raman    disruptive    colour    superposition    magnitude    mode    drawback    tissue    generates    broadband    spontaneous    coherent    speed    laser    hurdle    bulky    hours    healthy    diagnostic    setting    specificity    obtain    reliability    light    consuming    adoption    dual    nonlinear    graphene    inspection    immediately    passively    drastically    staining    informed    pulses    crs    lasers    heavily    acquisition   

Project "GSYNCOR" data sheet

The following table provides information about the project.

Coordinator
THE CHANCELLOR MASTERS AND SCHOLARSOF THE UNIVERSITY OF CAMBRIDGE 

Organization address
address: TRINITY LANE THE OLD SCHOOLS
city: CAMBRIDGE
postcode: CB2 1TN
website: www.cam.ac.uk

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country United Kingdom [UK]
 Total cost 149˙628 €
 EC max contribution 149˙628 € (100%)
 Programme 1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC))
 Code Call ERC-2018-PoC
 Funding Scheme ERC-POC
 Starting year 2019
 Duration (year-month-day) from 2019-06-01   to  2020-11-30

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    THE CHANCELLOR MASTERS AND SCHOLARSOF THE UNIVERSITY OF CAMBRIDGE UK (CAMBRIDGE) coordinator 149˙628.00

Map

 Project objective

The current standard of tumour diagnostics is histopathology, where excisions are taken from the tissue of a diseased patient, followed by staining and visual inspection. The process is time-consuming, costly, with low sensitivity and specificity. The results are subjective and qualitative, heavily depending on the judgement of the doctor. Spontaneous Raman microscopy is a label-free and non-invasive imaging technique, which enables to obtain objective and quantitative information on the tissue, by measuring its detailed molecular composition. It has proven capability to discriminate between healthy and tumour tissue and to identify the type and grade of tumour. Its main drawback is the very weak Raman signal, resulting in slow acquisition speed. This means that acquisition of a complete image would take up to several hours, prohibiting real-time and in vivo imaging. Coherent Raman scattering (CRS) generates the signal from a coherent superposition of the molecules in the tissue, illuminated by two synchronized ultrashort light pulses of different colour, thus improving by several orders of magnitude the acquisition speed. This enables real-time, in vivo imaging of the tissue allowing doctors to make informed diagnostic and/or therapeutic decisions immediately. The main hurdle of CRS microscopy, which has prevented its widespread adoption in a clinical setting, is the complexity and the high cost of the illuminating laser system, which is bulky and requires handling by specialized personnel. GSYNCOR aims to drastically simplify the laser system used for CRS microscopy, increasing its reliability and reducing its cost by exploiting the ultrafast and broadband nonlinear optical response of graphene. This enables not only pulsed (mode-locked) operation of a laser system, but also to passively synchronize two different lasers, generating the dual-wavelength pulses required for CRS. This will enable the uptake of CRS as a disruptive biomedical imaging technology.

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The information about "GSYNCOR" are provided by the European Opendata Portal: CORDIS opendata.

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