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RetinDR SIGNED

RetinDR: The first topical ophthalmic formulation (eye drops) that effectively prevents and/or treats the retinal neurodegeneration induced by diabetes (diabetic retinopathy) and/or aging

Total Cost €

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EC-Contrib. €

0

Partnership

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 RetinDR project word cloud

Explore the words cloud of the RetinDR project. It provides you a very rough idea of what is the project "RetinDR" about.

jobs    diabetic    21m    hypertension    successful    diabetes    markets    indicated    drug    antagonist    repurposing    seeing    quite    suffer    npv    royalties    feasibility    europeans    pulmonary    completion    ebitda    1    strategic    agreements    22    vision    blurred    98    endothelin    accounted    retinal    industrial    effectiveness    commercialisation    93    final    co    prevents    medical    double    outside    equalling    forecast    market    treatments    company    licensing    aged    receptor    difficulty    2025    months    business    81b    55m    reading    grow    sme    blindness    model    aggressive    cagr    commercialization    neurodegeneration    people    retindr    115    plan    worldwide    treats    spots    parent    share    formulation    5    drops    sales    52m    ophthalmic    dr    15    wacc    prevention    aging    retinopathy    substance    bosentan    revenues    limited    progresses    estimate    disease    receive    till    usually    considering    2016    global    mix    symptoms    adults    floaters    pharmaceutical    stages    eye    topical    3    million    irr    peripheral    treatment    arterial   

Project "RetinDR" data sheet

The following table provides information about the project.

Coordinator		 RETINSET SL 

Organization address
address: AMPOSTA 20
city: SANT CUGAT DEL VALLES
postcode: 8174
website: n.a.

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.
 Coordinator Country Spain [ES]
 Total cost 71˙429 €
 EC max contribution 50˙000 € (70%)
 Programme 1. H2020-EU.3. (PRIORITY 'Societal challenges)
2. H2020-EU.2.3. (INDUSTRIAL LEADERSHIP - Innovation In SMEs)
3. H2020-EU.2.1. (INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies)
 Code Call H2020-SMEInst-2018-2020-1
 Funding Scheme SME-1
 Starting year 2019
 Duration (year-month-day) from 2019-08-01   to  2020-01-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    RETINSET SL ES (SANT CUGAT DEL VALLES) coordinator 50˙000.00

Map

 Project objective

Diabetic retinopathy (DR) is the leading cause of blindness among working-aged adults. About 93 million people worldwide and 3%-4.1% of Europeans suffer this disease. The early stages of DR usually have no symptoms, however when the disease progresses it affects vision: blurred vision, seeing double, difficulty reading, spots or floaters in the field of vision, and loss of peripheral vision. Current treatments are quite aggressive, are only indicated in advanced stages of the disease, have significant side effects and their effectiveness is limited. RetinDR is a topical ophthalmic formulation (eye drops) that effectively prevents and/or treats the retinal neurodegeneration induced by diabetes (diabetic retinopathy) and/or aging. The pharmaceutical development of RetinDR is based on the repurposing of the drug substance bosentan (endothelin receptor antagonist, currently indicated for the pulmonary arterial hypertension treatment) for the prevention and treatment of DR.

The global DR market accounted for $5.81B in 2016 and is forecast to grow at 6.3%. CAGR till 2025. We estimate a market share of 0.115% 5 years after commercialisation, equalling revenues of 52M€. Our main business model will focus on sales and distribution of RetinDR in Europe through a distribution agreement with the parent company Medical Mix S.L. and co-development or licensing agreements with strategic industrial partners in markets outside of Europe where we will receive royalties.

With this model and the successful completion of the SME Phase 1 and 2 we estimate an EBITDA of over 55M€ in 5 years after commercialization an IRR of 98% and NPV of over 21M€ considering a WACC of 15%, creating 22 new jobs by 2025. The Feasibility Study for this project will take 6 months and focus on an in-depth market study, technical testing and the development of final business plan to take us to market.

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The information about "RETINDR" are provided by the European Opendata Portal: CORDIS opendata.

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