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Opendata, web and dolomites

PoreDetect SIGNED

Bench-top system for detection and analysis of miRNA using solid-state nanopores

Total Cost €

EC-Contrib. €

Partnership

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PoreDetect project word cloud

Explore the words cloud of the PoreDetect project. It provides you a very rough idea of what is the project "PoreDetect" about.

infections unprecedented consolidator molecular fast bacterial ultimately benchtop environmental personalised integral tracking nature proof machine device handheld wearable combine holds arxiv 2016 pairs 2015 poredetect erc single oligonucleotides cancer diagnostics biomarkers grant create microrna limited medicine mirna time resolution bulk revolutionising cell detection biological detecting markers cfrna molecule learning nanopore 2019 nanotechnology nano base quantification length jacs 2018 certain contaminants minutes molecules free hundreds letters versatile technique tens prevention promise disease statistics sensing designerpore

Project "PoreDetect" data sheet

The following table provides information about the project.

Coordinator	THE CHANCELLOR MASTERS AND SCHOLARSOF THE UNIVERSITY OF CAMBRIDGE Organization address address: TRINITY LANE THE OLD SCHOOLS city: CAMBRIDGE postcode: CB2 1TN website: www.cam.ac.uk contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.
Coordinator Country	United Kingdom [UK]
Total cost	0 €
EC max contribution	150˙000 € (0%)
Programme	1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC))
Code Call	ERC-2019-PoC
Funding Scheme	ERC-POC-LS
Starting year	2020
Duration (year-month-day)	from 2020-07-01 to 2021-12-31

Partnership

Take a look of project's partnership.

#	participants	country	role	EC contrib. [€]
1	THE CHANCELLOR MASTERS AND SCHOLARSOF THE UNIVERSITY OF CAMBRIDGE THE CHANCELLOR MASTERS AND SCHOLARSOF THE UNIVERSITY OF CAMBRIDGE Organization address address: TRINITY LANE THE OLD SCHOOLS city: CAMBRIDGE postcode: CB2 1TN website: www.cam.ac.uk contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	UK (CAMBRIDGE)	coordinator	150˙000.00

Map

Project objective

The fast and reliable detection of single molecules holds the promise of revolutionising diagnostics, disease prevention as well as biological research by offering unprecedented resolution compared to bulk approaches. Based on work done as part of the ‘DesignerPore’ ERC consolidator grant (Nature Nanotechnology 2016) we will develop a benchtop device capable of detecting hundreds of molecular targets within tens of minutes. We will combine our recent development in nanopore sensing technology (JACS 2015) with machine-learning (Nano Letters 2018) and advanced statistics (arxiv 2019) to create a new versatile single molecule technique. Ultimately, our PoreDetect technology has the potential to become an integral part of handheld or wearable devices allowing real time tracking of disease markers for personalised medicine, bacterial infections or environmental contaminants. While the technique is not limited to the detection of certain molecules, for this proof-of-concept we aim to focus on sensing short oligonucleotides tens of base pairs in length, with immediate applications in the quantification of cell-free (cfRNA) and microRNA (miRNA) as cancer biomarkers.

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The information about "POREDETECT" are provided by the European Opendata Portal: CORDIS opendata.