The page lists 113 projects related to the topic "aberrant".
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1 | aLzINK | Alzheimer's disease and Zinc: the missing link ? | 2015 |
2 | DNAendProtection | DNA end protection in Immunity and Cancer | 2015 |
3 | SOS | Sorting of Self | 2015 |
4 | EPICUP | Development of a ncRNA DNA Methylation Kit for the Diagnosis of Cancer of Unknown Primary | 2015 |
5 | EPIMAC | The next generation epigenetic medicine for inflammation | 2015 |
6 | GLYCANC | Matrix glycans as multifunctional pathogenesis factors and therapeutic targets in cancer | 2015 |
7 | STOPAPCG1IMP | Spatial-temporal regulation of APC/C, its role on G1 arrest and impact on terminal differentiation | 2015 |
8 | LARP4MOT | Structural and functional studies of LARP4, a new RNA binding protein involved in mRNA stabilisation and cell migration | 2016 |
9 | NeuroRhomboid | Discovering the signalling pathways and physiology of active rhomboid proteases in the brain | 2015 |
10 | Subpopulations | Investigating Fibrotic and Regenerative Fibroblast Populations in Muscular Dystrophy | 2016 |
11 | EGFR-Activ | Epidermal growth factor receptor (EGFR) activation by cytohesins - Structural Insights | 2015 |
12 | TWILIGHT | ToWards Immunisations that Last: the Immunology and Gerontology of Helper T cells | 2015 |
13 | FAtoUnFRAGILITY | Fanconi anemia : a disease model to understand causes and consequences of common fragile site instability. | 2015 |
14 | MechanoFate | From mechanical stress to vascular fate | 2016 |
15 | proLungPlasma | Validation of a Lung Cancer Plasma Reflex Test Using Epigenetic Biomarker for Cancer Detection | 2015 |
16 | IMMUNOBIOME | Identifying microbiotal triggers of inflammatory bowel disease through the lens of the immune system | 2016 |
17 | NutrientSensingVivo | The Physiology of Nutrient Sensing by mTOR | 2016 |
18 | rEnDOx | REDOX SIGNALING AND METABOLIC STATES IN ANGIOGENESIS IN HEALTH AND DISEASE | 2016 |
19 | SyBil-AA | Systems Biology of Alcohol Addiction: Modeling and validating disease state networks in human and animal brains for understanding pathophysiolgy, predicting outcomes and improving therapy | 2016 |
20 | REDOXCYCLE | The molecular interface between cell cycle and redox regulation | 2016 |
21 | ReachingCompleteness | The Molecular Basis of Somatic Nuclear Reprogramming | 2016 |
22 | CONTEXTVISION | Visual perception in Context | 2016 |
23 | LIPSYNING | Eat me microglia: lipid scrambling as a signal for synaptic pruning | 2016 |
24 | EpiMIRgen | A comprehensive analysis of microRNA-124 regulated gene networks and its role in epilepsy. | 2016 |
25 | MECHANOCHECK | ATR-mediated mechanotransduction and connections with the actin cytoskeleton | 2016 |
26 | RESHAPE | REstoring the Self with embodiable HAnd ProsthesEs | 2016 |
27 | WntELECT | Wnt Enhancer LandscapE CharacTerization | 2016 |
28 | BCM-UPS | Dissecting the role of the ubiquitin proteasome system in the pathogenesis and therapy of B-cell malignancies | 2016 |
29 | INTEGRAL | Signal Integration by Gene Regulatory Landscapes | 2016 |
30 | TransSplicHD | Single-Cell Transcriptomics and Spliceosome analysis to uncover new mechanisms of neuronal vulnerability to Huntington’s Disease. | 2016 |
31 | CoCa | Collagen in Cancer: from the regulatory fibril forming function of collagen V in development to its implication in tumor progression | 2016 |
32 | SYNDEGEN | Synaptic dysfunction in Neurodegenerative Diseases | 2017 |
33 | EXPECTBRAIN | How the human brain combines the certainty of prior expectations and the clarity of sensory input during speech perception | 2017 |
34 | ChromatinRemodelling | Single-Molecule And Structural Studies Of ATP-Dependent Chromatin Remodelling | 2017 |
35 | INSPIRED | Targeting IRE1 in disease | 2017 |
36 | EVALVE | Biomechanics and signaling in models of congenital heart valve defects | 2016 |
37 | Lifebrain | Healthy minds from 0-100 years: Optimising the use of European brain imaging cohorts | 2017 |
38 | PredAMEG | Identifying Oscillatory Signatures of Predictive Coding in Hierarchical Auditory Networks with MEG | 2017 |
39 | TEDCIP | Targeting epigenetic demethylases: development of covalent inhibitors and PROTACs (Proteolysis Targeting Chimeras). | 2017 |
40 | BRAVEST | Boosting Reward-based Attention through VEstibular STimulation | 2018 |
41 | LEUKEMIC-TEs | Unveiling the signature of transposable elements-derived transcripts – the transposcriptome – as a biomarker in human acute myeloid leukemia | 2017 |
42 | eWAD | Unbalanced Wnt signalling in AD: a DNA methylation effect | 2017 |
43 | MacroStability | Stability and dynamics at different spatial scales: From physiology to Alzheimer's degeneration | 2017 |
44 | SpliceCore | Functional dissection of core spliceosomal mutations causing Retinitis Pigmentosa. | 2017 |
45 | DNAmethAML | Investigation of aberrant DNA methylation in malignant haematopoiesis | 2018 |
46 | PhaseAge | The chemistry and physics of RNP granules: how they form, age and cause disease | 2017 |
47 | PCAGED-KI | Photocaged Kinase Inhibitors as Molecular Tools for Investigating Neurodegenerative Diseases | 2017 |
48 | DNAmod_PROPAGATION | Propagating DNA Modifications Across the Cell Cycle | 2018 |
49 | DUALITY | An Integrated Computational and Experimental Approach to Rapid Synthesis of Highly Selective Dual-Targeted HDAC/CK2, MMP2/CK2 Inhibitors | 2018 |
50 | IMMUNO-RQC | Role of Listerin ubiquitin ligase in MHC-I antigen presentation | 2017 |
51 | METCLL | Discovery and validation of ‘epidrivers’ of cancer evolution and resistance to therapy | 2018 |
52 | iAML-lncTARGET | Targeting the transcriptional landscape in infant AML | 2017 |
53 | HERPES | Herpesvirus Effectors of RNA synthesis, Processing, Export and Stability | 2017 |
54 | Secret Surface | The cell surface tetraspanin web drives tumour development and alters metabolic signalling | 2017 |
55 | VitASTEM | Regulation of Single Hematopoietic Stem Cells by Intake of Vitamin A | 2018 |
56 | GlycoEdit | New Chemical Tools for Precision Glycotherapy | 2017 |
57 | DRIVE | GUIDANCE AND FUNCTION OF REGENERATIVE FIBERS IN ADULT CNS | 2018 |
58 | FeelAgain | Restoring natural feelings from missing or damaged peripheral nervous system by model-driven neuroprosthesis | 2018 |
59 | GlycoSkin | Dissection of Glycan Function by Engineered Tissue Models | 2018 |
60 | SplicEcomplex | Deciphering the structure and dynamics of the early spliceosome assembly | 2018 |
61 | ConnectExAct-Age | Brain Connectivity for Executive Control over Action in Ageing | 2018 |
62 | ROCKSOFT | Rho GTPase cross-talk with syndecan-4 regulates pro-fibrotic mechanotransduction in the heart | 2019 |
63 | MS-fMRI-QSM | Studying Multiple Sclerosis with a novel simultaneous functional Magnetic Resonance Imaging (fMRI) and Quantitative Susceptibility Mapping (QSM) sequence. | 2019 |
64 | P-MaleReg | Establishment of P-element silencing in Drosophila simulans dysgenic males | 2019 |
65 | Gut-AnorexiaNervosa | Metagenomics and metabolomics studies of patients with Anorexia Nervosa to identify intestinal microbial mechanisms contributing to pathogenesis | 2018 |
66 | ProCenDecl | Synthesis and validation of chemical Probes for Centrosome Declustering: development of potent and selective anti-cancer agents. | 2019 |
67 | INFLA-AID | The role of NLRC4 inflammasome in autoinflammatory diseases | 2018 |
68 | AstroMiRimage | Super-resolution imaging to uncover microRNA control of astrocytes in epilepsy | 2018 |
69 | UNNAMEd-2 | Unraveling the conceptional novel ADAM17 regulation by PP2A in metastasis formation. | 2019 |
70 | EpiTFeb | Deciphering the Transcriptional Logic of TFEB activation in cell identity and cancer | 2018 |
71 | Newron-TBI | Neurogenesis-related changes in hippocampal new neurons and circuits after traumatic brain injury | 2018 |
72 | METHYVIREVOL | Virocellular hybrids and epigenomic changes as driving factors of infection driven cancers. | 2019 |
73 | TRANSREG | Dissecting the role of Translational Regulation in Tumorigenesis | 2018 |
74 | SRIMEM | Super-Resolution Imaging and Mapping of Epigenetic Modifications | 2018 |
75 | V.A. Cure | A multidisciplinary approach towards sustainable improvement in rare diseases care uniting Europe's top class vascular research to find new treatment strategies for vascular anomalies | 2019 |
76 | RxmiRcanceR | Tumor suppressive microRNAs for cancer therapy | 2018 |
77 | PoLiMeR | Polymers in the Liver: Metabolism and Regulation | 2018 |
78 | IM-ID | Defining the intrinsic transcriptional programs and the microenvironmental signals tailoring lung Interstitial Macrophage IDentity | 2019 |
79 | NextGen IO | Exploiting the hypoxia response in T cells for Next-Generation Immuno-Oncology | 2019 |
80 | HERMES | Hybrid Enhanced Regenerative Medicine Systems | 2019 |
81 | DisConn | Neural drivers of functional disconnectivity in brain disorders | 2019 |
82 | EPIORGABOLISM | Diabetic nephropathy modelling in hESC-derived 3D kidney organoids | 2019 |
83 | ProteoNE_dynamics | Surveillance mechanisms regulating nuclear envelope architecture and homeostasis | 2019 |
84 | Epi4MS | Targeting the epigenome: towards a better understanding of disease pathogenesis and novel therapeutic strategies in Multiple Sclerosis | 2019 |
85 | BioDisOrder | Order and Disorder at the Surface of Biological Membranes. | 2019 |
86 | SCAMPICITY | cAMP-dependend plasticity of striatal projection neurons in health and disease | 2019 |
87 | eXcape3D | Functional dissection of X-linked regulatory DNA: unravelling the impact of genome topology on transcriptional regulation | 2019 |
88 | RoBE | Study of the role of BANK1 in antibody production and antibody-independent functions of B cells in SLE | 2019 |
89 | Centromere Stability | Mechanisms that maintain centromere DNA repeats stability in human cells. | 2020 |
90 | iRhomADAM | Uncovering the role of the iRhom2-ADAM17 interaction in inflammatory signalling | 2020 |
91 | MGLycan | Targeting hMGL-GalNAc interactions to reverse immune suppression in cancer | 2019 |
92 | InvADeRS | Investigating the Activity of transposon Derived Regulatory Sequences in the placenta | 2019 |
93 | ARGONAUT | ARGONAUT: from the synthesis of gAnglioside tumouR antiGens to a platfOrm for caNcer Active immUnoTherapy | 2019 |
94 | ResonanceCircuits | Illuminating neural microcircuitry underlying flicker resonance in the visual cortex | 2020 |
95 | Prion Respiration | The Role of Complex I Assembly Factors during Prion Diseases: Insights into Mitochondrial Neurobiology | 2019 |
96 | RTTOPHAGY | """Investigating autophagy enhancement as a therapeutic approach for the treatment of Rett syndrome.""" | 2019 |
97 | PROTEUS | Predicting Routes Of Tumour Evolution driven by Unstable genomes and Selection | 2019 |
98 | MetEpiC | P53-dependent Metabolic and Epigenetic Reprogramming in Carcinogenesis | 2020 |
99 | ACoDM | Affective Control of Decision Making | 2019 |
100 | SECRET | Exploitation of the SECRETory pathway for cancer therapy to address European research | 2019 |
101 | NeutroCure | Development of “smart” amplifiers of reactive oxygen species specific to aberrant polymorphonuclear neutrophils for treatment of inflammatory and autoimmune diseases, cancer and myeloablation. | 2020 |
102 | RhabdoEvo | Deciphering the cellular origin and evolution of malignant rhabdoid tumors | 2019 |
103 | PRIME | Prevention and Remediation of Insulin Multimorbidity in Europe | 2020 |
104 | AND-PD | COMORBIDITY MECHANISMS OF ANXIETY AND PARKINSON’S DISEASE | 2020 |
105 | RiboTrace | Bridging temporal resolution gaps to dissect RNA silencing at the molecular and genomic scale | 2020 |
106 | ASTRA | ASsembly and phase Transitions of Ribonucleoprotein Aggregates in neurons: from physiology to pathology. | 2020 |
107 | MOBETA | Motor cortical beta bursts for movement planning and evaluation: Mechanisms, functional roles, and development | 2020 |
108 | GlioTarget | Inflaming the microenvironment of glioblastoma tumors by ADAR1 inhibition: a two-hit approach for the treatment of brain cancer. | 2021 |
109 | LAMININ | Light-switchable proteins and Adhesion Micropatterns to Illuminate the Navigation machInery of Neurons | 2020 |
110 | DREAM | Dux4-Regulated Expression and Activity by MATR3 | 2020 |
111 | PDASwITch | Super-enhancer modules controlling plasticity and response to therapy in pancreatic cancer | 2020 |
112 | ICG68-PROG | Imaging of c-Met aberrant cancers with Gallium-68 chelators for positron emission tomography | 2020 |
113 | ROSETTA | Deciphering the Role of aberrant glycOSylation in the rEsponse to Targeted TherApies for breast cancer | 2020 |