NANOBACTERPHAGESERS

Design of Novel Portable-Sensors Based on Suspension Arrays Composed of Monoclonal Antibody and Bacteriophage Carrying Magnetically Loaded Nanoparticles and Surface Enhanced Raman Spectroscopy

Coordinatore	HACETTEPE UNIVERSITESI    more  Organization address address: HACETTEPE UNIVERSITESI BEYTEPE KAMPUSU REKTORLUK BINASI city: CANKAYA ANKARA postcode: 6800 contact info Titolo: Prof. Nome: Erhan Cognome: Biskin Email: send email Telefono: 905327000000 Fax: 903123000000
Nazionalità Coordinatore	Turkey [TR]
Totale costo	1˙625˙723 €
EC contributo	1˙625˙723 €
Programma	FP7-PEOPLE Specific programme "People" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013)
Code Call	FP7-PEOPLE-2011-IAPP
Funding Scheme	MC-IAPP
Anno di inizio	2011
Periodo (anno-mese-giorno)	2011-11-01   -   2015-10-31

 Partecipanti

#	participant	country	role	EC contrib. [€]
1	HACETTEPE UNIVERSITESI  Organization address address: HACETTEPE UNIVERSITESI BEYTEPE KAMPUSU REKTORLUK BINASI city: CANKAYA ANKARA postcode: 6800 contact info Titolo: Prof. Nome: Erhan Cognome: Biskin Email: send email Telefono: 905327000000 Fax: 903123000000	TR (CANKAYA ANKARA)	coordinator	243˙328.80
2	UNIVERSITY OF BRIGHTON  Organization address address: "Lewes Road, Mithras House" city: BRIGHTON postcode: BN2 4AT contact info Titolo: Dr. Nome: Jonathan Cognome: Caplin Email: send email Telefono: 441274000000 Fax: 441274000000	UK (BRIGHTON)	participant	314˙998.20
3	APTARES AG  Organization address address: AM SCHEUNENVIERTEL 1 city: MITTENWALDE postcode: 15749 contact info Titolo: Ms. Nome: Claudia Cognome: Dahmen Email: send email Telefono: 491789000000 Fax: 49471681580	DE (MITTENWALDE)	participant	235˙096.40
4	Biyomedtek Biomedical Technologies Foundation Economical Enterprise  Organization address address: BEYSUKENT MAHALLESI DUMLUKA SOKAK 15 city: CANKAYA ANKARA postcode: 6800 contact info Titolo: Mr. Nome: Sinan Cognome: Egri Email: send email Telefono: 905338000000	TR (CANKAYA ANKARA)	participant	227˙757.20
5	GATE Elektronik Sanayi Ve Ticaret A.S  Organization address address: Istanbul Yolu Ayas Kav. 16. km 1-A city: Ankara postcode: 6370 contact info Titolo: Mr. Nome: Altug Cognome: Kuleng?r Email: send email Telefono: 903123000000 Fax: 903123000000	TR (Ankara)	participant	203˙956.50
6	Nome Ente NON disponibile  Organization address address: ESKISEHIR YOLU 8 KM city: ANKARA postcode: TR-06800 contact info Titolo: Prof. Nome: Abdullah Cognome: Atalar Email: send email Telefono: 903123000000	TR (ANKARA)	participant	201˙262.60
7	ELIAVA BIO PREPARATIONS LTD  Organization address address: GOTUA STREET 3 city: TBILISI postcode: 160 contact info Titolo: Mrs. Nome: Nina Cognome: Chanishvili Email: send email Telefono: +995 32 381068	GE (TBILISI)	participant	199˙323.30

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 Obiettivo del progetto (Objective)

'In this project, we aim to develop nanotechnology-based systems for detection of pathogenic bacteria in several aqueous media mainly in environmental water based on suspension arrays together with a portable custom-designed detection system. The six objectives (six work packages) are as follows: (i) Nanostructured sensors surfaces, in which electron-beam, photo-, soft and dip-pen lithographies will be applied in the fabrication of functionalized low-cost (disposable) SERS substrates, specially designed for simultaneus Raman and Fluorescence enhancement; (ii) nanosorbents and their mixtures as suspension arrays against the target bacteria for capturing units in which firstly magnetically loaded nanoparticles will be produced and labelled/barcoaded with fluorosence dies and/or quantum dots and then bacteriophages, monoclonal antibodies, and/or aptamers will be immobilized onto these nanoparticles as bioligands to recognize and capture the target bacteria specifically; their mixtures will form the suspension arrays; (iii) target bacteria and bacteriophages; the target bacteria (as water pollutants), are Escherichia coli, Enterococcus species and Bacteroides ovatus; bacteriophages which will recognize these bacteria will be selected/produced as bioligands; (iv) aptamers; they will be selected/modified/produced; (v) sensors/array systems; a portable “Raman Spectrometer/Fluorescence Detector System” will be designed/produced that will be used together with the nanostructured sensors platforms, and finally (vi) validation; the materials and systems developed will be validated. This is a multidisciplinary and technological project and therefore brings together experts from different disciplines both from academia and industry. Basicly, the knowledge that will be developed/ accumulated at lab scale during the project will be transfered to the industrial partners for prototype productions, and then these will bring back to the academical institutions for validation tests.'