NANOBACTERPHAGESERS
Design of Novel Portable-Sensors Based on Suspension Arrays Composed of Monoclonal Antibody and Bacteriophage Carrying Magnetically Loaded Nanoparticles and Surface Enhanced Raman Spectroscopy
| Coordinatore | HACETTEPE UNIVERSITESI
Organization address
address: HACETTEPE UNIVERSITESI BEYTEPE KAMPUSU REKTORLUK BINASI contact info |
| Nazionalità Coordinatore | Turkey [TR] |
| Totale costo | 1˙625˙723 € |
| EC contributo | 1˙625˙723 € |
| Programma | FP7-PEOPLE
Specific programme "People" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013) |
| Code Call | FP7-PEOPLE-2011-IAPP |
| Funding Scheme | MC-IAPP |
| Anno di inizio | 2011 |
| Periodo (anno-mese-giorno) | 2011-11-01 - 2015-10-31 |
Partecipanti
| # | ||||
|---|---|---|---|---|
| 1 |
HACETTEPE UNIVERSITESI
Organization address
address: HACETTEPE UNIVERSITESI BEYTEPE KAMPUSU REKTORLUK BINASI contact info |
TR (CANKAYA ANKARA) | coordinator | 243˙328.80 |
| 2 |
UNIVERSITY OF BRIGHTON
Organization address
address: "Lewes Road, Mithras House" contact info |
UK (BRIGHTON) | participant | 314˙998.20 |
| 3 |
APTARES AG
Organization address
address: AM SCHEUNENVIERTEL 1 contact info |
DE (MITTENWALDE) | participant | 235˙096.40 |
| 4 |
Biyomedtek Biomedical Technologies Foundation Economical Enterprise
Organization address
address: BEYSUKENT MAHALLESI DUMLUKA SOKAK 15 contact info |
TR (CANKAYA ANKARA) | participant | 227˙757.20 |
| 5 |
GATE Elektronik Sanayi Ve Ticaret A.S
Organization address
address: Istanbul Yolu Ayas Kav. 16. km 1-A contact info |
TR (Ankara) | participant | 203˙956.50 |
| 6 |
Nome Ente NON disponibile
Organization address
address: ESKISEHIR YOLU 8 KM contact info |
TR (ANKARA) | participant | 201˙262.60 |
| 7 |
ELIAVA BIO PREPARATIONS LTD
Organization address
address: GOTUA STREET 3 contact info |
GE (TBILISI) | participant | 199˙323.30 |
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Obiettivo del progetto (Objective)
'In this project, we aim to develop nanotechnology-based systems for detection of pathogenic bacteria in several aqueous media mainly in environmental water based on suspension arrays together with a portable custom-designed detection system. The six objectives (six work packages) are as follows: (i) Nanostructured sensors surfaces, in which electron-beam, photo-, soft and dip-pen lithographies will be applied in the fabrication of functionalized low-cost (disposable) SERS substrates, specially designed for simultaneus Raman and Fluorescence enhancement; (ii) nanosorbents and their mixtures as suspension arrays against the target bacteria for capturing units in which firstly magnetically loaded nanoparticles will be produced and labelled/barcoaded with fluorosence dies and/or quantum dots and then bacteriophages, monoclonal antibodies, and/or aptamers will be immobilized onto these nanoparticles as bioligands to recognize and capture the target bacteria specifically; their mixtures will form the suspension arrays; (iii) target bacteria and bacteriophages; the target bacteria (as water pollutants), are Escherichia coli, Enterococcus species and Bacteroides ovatus; bacteriophages which will recognize these bacteria will be selected/produced as bioligands; (iv) aptamers; they will be selected/modified/produced; (v) sensors/array systems; a portable “Raman Spectrometer/Fluorescence Detector System” will be designed/produced that will be used together with the nanostructured sensors platforms, and finally (vi) validation; the materials and systems developed will be validated. This is a multidisciplinary and technological project and therefore brings together experts from different disciplines both from academia and industry. Basicly, the knowledge that will be developed/ accumulated at lab scale during the project will be transfered to the industrial partners for prototype productions, and then these will bring back to the academical institutions for validation tests.'