EPIC-CVD
EPIC-CVD: Individualised CVD risk assessment: tailoring targeted and cost-effective approaches to Europe's diverse populations
| Coordinatore | THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE
Organization address
address: The Old Schools, Trinity Lane contact info |
| Nazionalità Coordinatore | United Kingdom [UK] |
| Sito del progetto | http://www.epiccvd.eu/ |
| Totale costo | 7˙947˙602 € |
| EC contributo | 5˙987˙266 € |
| Programma | FP7-HEALTH
Specific Programme "Cooperation": Health |
| Code Call | FP7-HEALTH-2011-two-stage |
| Funding Scheme | CP-FP |
| Anno di inizio | 2012 |
| Periodo (anno-mese-giorno) | 2012-01-01 - 2015-12-31 |
Partecipanti
| # | ||||
|---|---|---|---|---|
| 1 |
THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE
Organization address
address: The Old Schools, Trinity Lane contact info |
UK (CAMBRIDGE) | coordinator | 2˙582˙778.45 |
| 2 |
VITAS AS
Organization address
address: GAUSTADALLEEN 21 contact info |
NO (OSLO) | participant | 1˙073˙697.90 |
| 3 |
BRAINSHAKE OY
Organization address
address: VUOLIAISTIE 15 contact info |
FI (OULU) | participant | 777˙000.00 |
| 4 |
MEDICAL RESEARCH COUNCIL
Organization address
address: NORTH STAR AVENUE POLARIS HOUSE contact info |
UK (SWINDON) | participant | 411˙174.30 |
| 5 |
UNIVERSITAIR MEDISCH CENTRUM UTRECHT
Organization address
address: HEIDELBERGLAAN 100 contact info |
NL (UTRECHT) | participant | 206˙684.40 |
| 6 |
IMPERIAL COLLEGE OF SCIENCE, TECHNOLOGY AND MEDICINE
Organization address
address: SOUTH KENSINGTON CAMPUS EXHIBITION ROAD contact info |
UK (LONDON) | participant | 196˙416.00 |
| 7 |
CENTRE INTERNATIONAL DE RECHERCHE SUR LE CANCER
Organization address
address: Cours Albert-Thomas 150 contact info |
FR (LYON CEDEX 08) | participant | 159˙500.40 |
| 8 |
ESCUELA ANDALUZA DE SALUD PUBLICA SA
Organization address
address: CUESTA DEL OBSERVATORIO CAMPUS UNIVERSITARIO CARTUJA 4 contact info |
ES (GRANADA) | participant | 145˙689.75 |
| 9 |
RAND EUROPE COMMUNITY INTEREST COMPANY
Organization address
address: Westbrook Centre Milton Road contact info |
UK (CAMBRIDGE) | participant | 74˙750.00 |
| 10 |
LUNDS UNIVERSITET
Organization address
address: Paradisgatan 5c contact info |
SE (LUND) | participant | 59˙314.80 |
| 11 |
AARHUS UNIVERSITET
Organization address
address: Nordre Ringgade 1 contact info |
DK (AARHUS C) | participant | 51˙057.20 |
| 12 |
FOUNDATION FOR GENOMICS & POPULATION HEALTH
Organization address
address: WORTS CAUSEWAY 2 contact info |
UK (CAMBRIDGE) | participant | 47˙276.40 |
| 13 |
HELLENIC HEALTH FOUNDATION
Organization address
address: KAISAREIAS 13 & ALEXANDROUPOLEOS contact info |
EL (ATHENS) | participant | 27˙258.00 |
| 14 |
HUMAN GENETICS FOUNDATION
Organization address
address: VIA NIZZA 52 contact info |
IT (TORINO) | participant | 23˙644.80 |
| 15 |
DEUTSCHES INSTITUT FUER ERNAEHRUNGSFORSCHUNG POTSDAM REHBRUECKE
Organization address
address: Arthur-Scheunert-Allee 114-116 contact info |
DE (NUTHETAL) | participant | 23˙544.00 |
| 16 |
UMEA UNIVERSITET
Organization address
address: UNIVERSITETOMRADET contact info |
SE (UMEA) | participant | 18˙511.20 |
| 17 |
THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD
Organization address
address: University Offices, Wellington Square contact info |
UK (OXFORD) | participant | 10˙520.40 |
| 18 |
FUNDACION PARA LA FORMACION E INVESTIGACION SANITARIAS DE LA REGION DE MURCIA
Organization address
address: CALLE LUIS FONTES PAGAN 9 contact info |
ES (MURCIA) | participant | 10˙222.80 |
| 19 |
CONSEJERIA DE SALUD Y SERVICIOS SANITARIOS - Principado de Asturias
Organization address
address: Ciriaco Miguel Vigil 9 contact info |
ES (Oviedo) | participant | 10˙020.50 |
| 20 |
RIJKSINSTITUUT VOOR VOLKSGEZONDHEIDEN MILIEU*NATIONAL INSTITUTEFOR PUBLIC HEALTH AND THE ENVIRONMENTEN
Organization address
address: Antonie Van Leeuwenhoeklaan 9 contact info |
NL (BILTHOVEN) | participant | 9˙585.00 |
| 21 |
FONDAZIONE IRCCS ISTITUTO NAZIONALE DEI TUMORI
Organization address
address: Via Venezian 1 contact info |
IT (Milan) | participant | 9˙111.06 |
| 22 |
ASOCIACION INSTITUTO BIODONOSTIA
Organization address
address: Paseo Dr. Beguiristain s/n contact info |
ES (DONOSTIA-SAN SEBASTIAN) | participant | 8˙898.00 |
| 23 |
ISTITUTO PER LO STUDIO E LA PREVENZIONE ONCOLOGICA
Organization address
address: VIA COSIMO IL VECCHIO 2 contact info |
IT (Florence) | participant | 8˙792.01 |
| 24 |
ORGANISMO AUTONOMO INSTITUTO DE SALUD PUBLICA Y LABORAL DE NAVARRA
Organization address
address: CL LEYRE 15 contact info |
ES (PAMPLONA) | participant | 8˙642.00 |
| 25 |
DEUTSCHES KREBSFORSCHUNGSZENTRUM
Organization address
address: Im Neuenheimer Feld 280 contact info |
DE (HEIDELBERG) | participant | 8˙421.00 |
| 26 |
ASSOCIAZIONE IBLEA PER LA RICERCA EPIDEMIOLOGICA ONLUS
Organization address
address: PIAZZA ANCIONE 2 contact info |
IT (RAGUSA) | participant | 8˙387.00 |
| 27 |
UNIVERSITA DEGLI STUDI DI NAPOLI FEDERICO II.
Organization address
address: Corso Umberto I 40 contact info |
IT (NAPOLI) | participant | 8˙194.08 |
| 28 |
UNIVERSITETET I TROMSOE
Organization address
address: Hansine Hansens veg 14 contact info |
NO (TROMSO) | participant | 8˙173.02 |
| 29 |
FUNDACION PUBLICA MIGUEL SERVET
Organization address
address: C/IRUNLARREA 3 contact info |
ES (PAMPLONA) | participant | 0.00 |
| 30 |
THE UNIVERSITY OF AUCKLAND
Organization address
address: PRINCES STREET 24 contact info |
NZ (AUCKLAND) | participant | 0.00 |
Mappa
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Obiettivo del progetto (Objective)
'EPIC-CVD's overarching goal is to provide clinicians and policy-makers with a menu of evidence-based options for cost-effective individualised risk assessment that enables the EU's increasingly resource-constrained economies to achieve more personalised predictive medicine in harmony with Europe's diverse cultures and healthcare systems.
We will achieve this through developing and validating innovative risk scores and efficient screening strategies by studying 75 high priority soluble biomarkers and 215,000 carefully selected genetic variants in the most powerful population-based prospective study ever conducted of incident coronary heart disease, stroke, and type 2 diabetes across 10 diverse European countries. EPIC-CVD will provide the first consideration across Europe of risk scores with information on the interplay of nature and nurture together with biomarkers of lifestyle, biological pathways, vascular injury, and ageing.
Our multidisciplinary consortium involves world-leading expertise in population health science, laboratory science (including VITAS, an SME partner, renowned for nutritional biomarker assays), translational science, and implementation science. This rare combination of expertise will enable systematic consideration of the implications of risk scores and screening strategies for predictive accuracy, feasibility, safety, acceptability, and cost-effectiveness. The impact on clinical decision making and clinical outcomes will be demonstrated in a new randomised trial of risk scores in relation to 'patient-centred' outcomes that assess attitudes, behaviours, and biological risk factors.
Key stakeholders (eg, healthcare professionals, regulators, industry) will be closely engaged by the project. Policy recommendations mindful of the broader societal implications of targeted screening will be tailored to Europe's diverse needs and systematically disseminated to various audiences. This initiative will derive major synergy from related efforts.'