FECUND
Optimisation of early reproductive success in dairy cattle through the definition of new traits and improved reproductive biotechnology
| Coordinatore | Fondazione Parco Tecnologico Padano
Organization address
address: Via Einstein - Loc. Cascina Codazza contact info |
| Nazionalità Coordinatore | Italy [IT] |
| Totale costo | 3˙912˙282 € |
| EC contributo | 2˙999˙393 € |
| Programma | FP7-KBBE
Specific Programme "Cooperation": Food, Agriculture and Biotechnology |
| Code Call | FP7-KBBE-2012-6-singlestage |
| Funding Scheme | CP-TP |
| Anno di inizio | 2013 |
| Periodo (anno-mese-giorno) | 2013-02-01 - 2017-01-31 |
Partecipanti
| # | ||||
|---|---|---|---|---|
| 1 |
Fondazione Parco Tecnologico Padano
Organization address
address: Via Einstein - Loc. Cascina Codazza contact info |
IT (Lodi) | coordinator | 712˙832.00 |
| 2 |
UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN
Organization address
address: BELFIELD contact info |
IE (DUBLIN) | participant | 485˙200.00 |
| 3 |
LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN
Organization address
address: GESCHWISTER SCHOLL PLATZ 1 contact info |
DE (MUENCHEN) | participant | 301˙932.50 |
| 4 |
UNION NATIONALE DES COOPERATIVES AGRICOLES D'ELEVAGE ET D'INSEMINATION ANIMALE
Organization address
address: Rue de Bercy 149 contact info |
FR (Paris) | participant | 288˙037.70 |
| 5 |
AVANTEA srl
Organization address
address: via Cabrini 12 contact info |
IT (Cremona) | participant | 285˙000.00 |
| 6 |
INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE
Organization address
address: Rue De L'Universite 147 contact info |
FR (PARIS CEDEX 07) | participant | 264˙750.80 |
| 7 |
VETERINAERMEDIZINISCHE UNIVERSITAET WIEN
Organization address
address: Veterinaerplatz 1 contact info |
AT (VIENNA) | participant | 248˙280.00 |
| 8 |
Instytut Genetyki i Hodowli Zwierzat Polskiej Akademii Nauk
Organization address
address: Postepu 1 contact info |
PL (Jastrzebiec) | participant | 210˙000.00 |
| 9 |
UNIVERSITA CATTOLICA DEL SACRO CUORE
Organization address
address: Largo Agostino Gemelli 1 contact info |
IT (MILANO) | participant | 100˙000.00 |
| 10 |
EUROPEAN FORUM OF FARM ANIMAL BREEDERS
Organization address
address: DREIJENLAAN 2K 1060 1061 contact info |
NL (WAGENINGEN) | participant | 49˙600.00 |
| 11 |
NATIONAL CATTLE BREEDING CENTRE LIMITED
Organization address
address: KILCORNEY contact info |
IE (ENFIELD) | participant | 20˙040.00 |
| 12 |
BAYERN GENETIK GMBH
Organization address
address: GUT ALTENBACH contact info |
DE (LANDSHUT) | participant | 19˙440.00 |
| 13 |
OSRODEK HODOWLI ZARODOWEJ OSIECINYSP ZOO
Organization address
address: UL WLOCLAWSKA 2 contact info |
PL (OSIECINY) | participant | 14˙280.00 |
Mappa
Word cloud
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Obiettivo del progetto (Objective)
'Good fertility is essential for the sustainability of livestock production. Of all livestock sectors, fertility of dairy cattle is raising the greatest cause for concern. Cow fertility has declined, particularly in Holstein cattle, from 80% pregnancy to first service 20 years ago to less than 40% today. Poor fertility is one of the main reasons for early culling, such that modern dairy cows complete fewer than 3 lactations, on average. The FECUND project will address the metabolic and genetic causes of low reproductive success of dairy cows in an interdisciplinary approach that will integrate in vivo and in vitro studies, biology, physiology, -omics technologies and bioinformatics. FECUND will focus on the early phases of reproduction from oocyte development to implantation of the conceptus. Starting from biological materials produced from high and low genetic merit cattle and from cows under energy stress of early lactation vs dry cows and heifers, FECUND will study, independently, the effects of genetics and metabolic stress on reproductive physiology to identify factors and early markers associated with high and low developmental potential, and with positive mother-conceptus interaction during the early stages of reproduction. These data will be mined to reveal physiological pathways and key candidate genes controlling variations of fertility. The biological knowledge created on early reproductive events in vivo will be validated in vitro, and extended to create further knowledge on the effects of the local environment on oocyte and embryo programming at the epigenetic level. Validated information will be used to improve herd management, gene assisted and genomic selection and assisted reproductive technologies, from in vitro ooctye maturation to optimised embryo culture. Information on biomarkers, indicator traits and improvements in assisted reproduction will be translated to applications that can be immediately implemented by SMEs.'
Introduzione (Teaser)
The FECUND EU project is addressing the improvement of fertility in dairy cows by creating a better understanding of the metabolic and genetic causes of the worldwide decrease in dairy cow fertility, which has been associated with the intensive selection for increased milk production.