IMPACT

Innovative Modelling for Pharmacological Advances through Collaborative Training

Coordinatore	THE UNIVERSITY OF WARWICK    more  Organization address address: Kirby Corner Road - University House - city: COVENTRY postcode: CV4 8UW contact info Titolo: Dr. Nome: Peter Cognome: Hedges Email: send email Telefono: +44 24765 23716 Fax: +44 24765 24991
Nazionalità Coordinatore	United Kingdom [UK]
Sito del progetto	http://www.csr-impact.eu
Totale costo	1˙467˙958 €
EC contributo	1˙467˙958 €
Programma	FP7-PEOPLE Specific programme "People" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013)
Code Call	FP7-PEOPLE-2012-ITN
Funding Scheme	MC-ITN
Anno di inizio	2013
Periodo (anno-mese-giorno)	2013-01-01   -   2016-12-31

 Partecipanti

#	participant	country	role	EC contrib. [€]
1	THE UNIVERSITY OF WARWICK  Organization address address: Kirby Corner Road - University House - city: COVENTRY postcode: CV4 8UW contact info Titolo: Dr. Nome: Peter Cognome: Hedges Email: send email Telefono: +44 24765 23716 Fax: +44 24765 24991	UK (COVENTRY)	coordinator	1˙467˙958.80
2	ASTRAZENECA AB  Organization address address: Vastra Maelarhamnen city: SODERTAELJE postcode: 151 85 contact info Titolo: Dr. Nome: Sandra Cognome: Visser Email: send email Telefono: +46 855324436	SE (SODERTAELJE)	participant	0.00

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 Obiettivo del progetto (Objective)

'This project forms an interdisciplinary collaborative partnership between AstraZeneca (AZ, Sweden) and the University of Warwick (UoW, UK) to train Early Stage Researchers (ESRs) in systems modelling tools and techniques enabling them to perform research projects at the forefront of international pharmacokinetic (PK) and pharmacodynamic (PD) analysis. This project will build upon extremely strong research and training links already formed between the UoW and AZ (UK) in PK/PD modelling and will support the clearly identified need within AZ worldwide to train more personnel with high-level skills in systems modelling for future drug development. The most effective drugs are those that produce clinical benefit by modulating disease biology and are given to patients at an optimal dose and schedule. In order to deliver new drugs it is necessary to quantify, translate and simulate from the test tube to the patient. This includes being able to model biological pathways, quantify relationships between dose/exposure, target engagement, efficacy and safety in pre-clinical tests and humans and utilising all relevant information efficiently and quantitatively. The development and application of innovative modelling techniques to tackle current problems in drug development allied to the training of researchers with skills to perform these tasks are key drivers for the partners. A unique blend of multidisciplinary training will be offered to the ESRs by both partners through well-established, extensive and innovative programmes at their sites with the appointed ESRs registered for PhDs at the UoW. The ESR projects will be based on research problems and data generated at AZ. The outcomes of the projects will not only maintain the positions of AZ and the UoW at the forefront of international research in PK/PD analysis, but also greatly enhance the EU’s standing worldwide in this area, whilst also enhancing the future job prospects of those trained within the AZ group worldwide'