CAReIOCA
Non-Invasive Optical Biopsy for Cancer Assessment using ultra high resolution Full-Field Optical Coherence Tomography
| Coordinatore | LLTECH MANAGEMENT SAS
Organization address
city: Paris contact info |
| Nazionalità Coordinatore | France [FR] |
| Totale costo | 4˙075˙420 € |
| EC contributo | 3˙099˙481 € |
| Programma | FP7-ICT
Specific Programme "Cooperation": Information and communication technologies |
| Code Call | FP7-ICT-2011-8 |
| Funding Scheme | CP |
| Anno di inizio | 2012 |
| Periodo (anno-mese-giorno) | 2012-11-01 - 2015-10-31 |
Partecipanti
| # | ||||
|---|---|---|---|---|
| 1 |
LLTECH MANAGEMENT SAS
Organization address
city: Paris contact info |
FR (Paris) | coordinator | 0.00 |
| 2 |
ACADEMISCH ZIEKENHUIS LEIDEN - LEIDS UNIVERSITAIR MEDISCH CENTRUM
Organization address
address: Albinusdreef contact info |
NL (LEIDEN) | participant | 0.00 |
| 3 |
ADIMEC ADVANCED IMAGE SYSTEMS BV
Organization address
address: LUCHTHAVENWEG contact info |
NL (EINDHOVEN) | participant | 0.00 |
| 4 |
CMOSIS NV
Organization address
address: COVELIERSTRAAT contact info |
BE (BERCHEM) | participant | 0.00 |
| 5 |
INSTITUT GUSTAVE ROUSSY
Organization address
address: Rue Camille Desmoulins contact info |
FR (VILLEJUIF) | participant | 0.00 |
Mappa
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Obiettivo del progetto (Objective)
Along the cancer care workflow, existing preoperative and intraoperative procedures such as the identification of small tumourous areas or the precise resection of tumors show significant fail rates, due to the inability of current imaging techniques to perform a reliable in situ diagnosis. Moreover the complete pathological diagnosis, often based on histology slides preparation, is usually only available after a few days. For these reasons a significant number of patients need to undergo secondary biopsy or surgery.nThe CAReIOCA project aims at providing pathologists and/or surgeons novel non-invasive optical imaging at the cellular scale for fast cancer assessment. By providing images approaching the level of information of histology slides during localization, biopsy and resection procedures in real or near-real time, the technique is expected to significantly improve cancer care. The project will combine latest advances in CMOS technology and 'optical biopsy' techniques to overcome the current technical limitations of an unequalled performance non-invasive tissue imaging technique: Full-Field Optical Coherence Tomography (FFOCT). The key technological achievement of the project will consist of the development of a specific high-performance CMOS smart camera, and will lead to the development, clinical adaptation and pre-clinical validation of a novel optical biopsy probe, exhibiting in-depth imaging capabilities and a record 3D resolution.nThe technique will provide a fast and reliable method to visualize pathological or suspicious areas, and corresponding microstructures, in real-time. In particular, it will enable pre-operative diagnosis, biopsy guidance, as well as intra-operative, large-scale surgical margin assessment. These applications are expected to significantly reduce reoperation rates of corresponding procedures. In this view, pre-clinical validation on Oral and Breast Cancer will be performed.