GLYCOPHARM

The Sugar Code: from (bio)chemical concept to clinics

Coordinatore	AGENCIA ESTATAL CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS    more  Organization address address: CALLE SERRANO 117 city: MADRID postcode: 28006 contact info Titolo: Ms. Nome: Ana Maria Cognome: De La Fuente Email: send email Telefono: +34 91 5681709 Fax: +34 91 568 1442
Nazionalità Coordinatore	Spain [ES]
Totale costo	3˙005˙458 €
EC contributo	3˙005˙458 €
Programma	FP7-PEOPLE Specific programme "People" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013)
Code Call	FP7-PEOPLE-2012-ITN
Funding Scheme	MC-ITN
Anno di inizio	2012
Periodo (anno-mese-giorno)	2012-11-01   -   2016-10-31

 Partecipanti

#	participant	country	role	EC contrib. [€]
1	AGENCIA ESTATAL CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS  Organization address address: CALLE SERRANO 117 city: MADRID postcode: 28006 contact info Titolo: Ms. Nome: Ana Maria Cognome: De La Fuente Email: send email Telefono: +34 91 5681709 Fax: +34 91 568 1442	ES (MADRID)	coordinator	1˙047˙070.94
2	UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN  Organization address address: BELFIELD city: DUBLIN postcode: 4 contact info Titolo: Mr. Nome: Donal Cognome: Doolan Email: send email Telefono: +353 1 7161656	IE (DUBLIN)	participant	435˙025.91
3	LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN  Organization address address: GESCHWISTER SCHOLL PLATZ 1 city: MUENCHEN postcode: 80539 contact info Titolo: Prof. Nome: Hans-Joachim Cognome: Gabius Email: send email Telefono: +49 89 21802290	DE (MUENCHEN)	participant	235˙268.88
4	UNIVERSITAETSKLINIKUM HEIDELBERG  Organization address address: IM NEUENHEIMER FELD 672 city: HEIDELBERG postcode: 69120 contact info Titolo: Mr. Nome: Thomas Cognome: Eisenhauer Email: send email Telefono: +49 6221 567324 Fax: +49 6221 565460	DE (HEIDELBERG)	participant	235˙268.88
5	UNIVERSIDADE DO MINHO  Organization address address: Largo do Paco city: BRAGA postcode: 4704553 contact info Titolo: Prof. Nome: Vasco Manuel Cognome: Teixeira Email: send email Telefono: +351 253 601118 Fax: +351 253 601059	PT (BRAGA)	participant	219˙681.00
6	UNIVERZITA KARLOVA V PRAZE  Organization address address: Ovocny trh 5 city: PRAHA 1 postcode: 11636 contact info Titolo: Mrs. Nome: Kristyna Cognome: Matejkova Email: send email Telefono: 420225000000 Fax: 420225000000	CZ (PRAHA 1)	participant	218˙408.52
7	TOSCANA BIOMARKERS S.R.L  Organization address address: VIA FIORENTINA 1 city: SIENA postcode: 53100 contact info Titolo: Dr. Nome: Maria Claudia Cognome: Alcaro Email: send email Telefono: 390577000000 Fax: 390577000000	IT (SIENA)	participant	187˙062.70
8	ROCHE DIAGNOSTICS GMBH  Organization address address: Sandhofer Strasse 116 city: MANNHEIM postcode: 68305 contact info Titolo: Dr. Nome: Stefan Cognome: Weigand Email: send email Telefono: +49 8856604749	DE (MANNHEIM)	participant	172˙200.60
9	INSTITUTE OF APPLIED BIOTECHNOLOGIES AS  Organization address address: Tymianova 619/14 city: PRAHA postcode: 10100 contact info Titolo: Dr. Nome: Milan Cognome: Press Email: send email Telefono: +420 255 700 885 Fax: +420 272 701 742	CZ (PRAHA)	participant	158˙849.91
10	FUNDACION UNIVERSITARIA SAN PABLO-CEU  Organization address address: ISAAC PERAL 58 city: MADRID postcode: 28040 contact info Titolo: Mr. Nome: Javier Cognome: Cabero Alonso Email: send email Telefono: +34 913724772	ES (MADRID)	participant	96˙620.96
11	ISOSEP AKTIEBOLAG  Organization address address: DALKARRSVAGEN 11 city: TULLINGE postcode: 146 36 contact info Titolo: Dr. Nome: Roland Cognome: Stenutz Email: send email Telefono: +46 8 778 22 32 Fax: +46 8 778 22 32	SE (TULLINGE)	participant	0.00

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 Obiettivo del progetto (Objective)

'Coding of biochemical information is commonly described to be based solely on nucleotides and amino acids, whereas carbohydrates, the most abundant type of molecule in Nature, appear sidelined in this respect. That carbohydrates, as part of cellular glycoconjugates, have exceptional talents for building biochemical signals is an emerging insight, at the heart of the concept of the Sugar Code. Intuitively, emergence of recognition partners for information transfer is expected, and this is the case. Thus, coding of bioinformation in glycans and information transfer via lectins is key to a wealth of medically relevant processes, e.g. infection, immune regulation and malignancy, now awaiting its full exploitation pharmaceutically. To do so, training in this exceptionally interdisciplinary field needs to be provided. With this aim, scientific and country/gender issues are strategically combined in this network. Its composition assures a continuous chain of research expertise, from computational and synthetic chemistry to state of the art biophysical chemistry and structural biology, then to biochemistry, molecular cell biology and pharmaceutical/biomedical sciences, generating innovative clinical approaches. Notably, academia is linked with industry, bringing in the essence of business acumen into the training programme. This activity and the research deliberately planned as interdisciplinary projects ensure an optimal training for young researchers in a dynamically developing area of conspicuous biopharmaceutical potential. Equally important, it lays the foundation to inspire novel strategies for the design of potent and selective inhibitors against lectins and the development of lectins (or suitably engineered variant(s)) as therapeuticals. As a boon for the success of the network, cooperations between several partners have already proven successful, especially increasing the core in Madrid and partners in Dublin, Munich and Prague.'