ISD

Intelligent Surgical Device

Coordinatore	MEDIMASS KUTATO FEJLESZTO ES SZOLGALTATO KFT    more  Organization address address: REMENYI EDE UTCA 2 city: BUDAPEST postcode: 1033 contact info Titolo: Mr. Nome: Akos Cognome: Tallos Email: send email Telefono: 36306364306
Nazionalità Coordinatore	Hungary [HU]
Totale costo	4˙252˙802 €
EC contributo	2˙967˙103 €
Programma	FP7-HEALTH Specific Programme "Cooperation": Health
Code Call	FP7-HEALTH-2012-INNOVATION-1
Funding Scheme	CP-FP
Anno di inizio	2013
Periodo (anno-mese-giorno)	2013-01-01   -   2014-12-31

 Partecipanti

#	participant	country	role	EC contrib. [€]
1	MEDIMASS KUTATO FEJLESZTO ES SZOLGALTATO KFT  Organization address address: REMENYI EDE UTCA 2 city: BUDAPEST postcode: 1033 contact info Titolo: Mr. Nome: Akos Cognome: Tallos Email: send email Telefono: 36306364306	HU (BUDAPEST)	coordinator	1˙640˙250.80
2	IMPERIAL COLLEGE OF SCIENCE, TECHNOLOGY AND MEDICINE  Organization address address: SOUTH KENSINGTON CAMPUS EXHIBITION ROAD city: LONDON postcode: SW7 2AZ contact info Titolo: Dr. Nome: Zoltan Cognome: Takats Email: send email Telefono: 442076000000 Fax: 442076000000	UK (LONDON)	participant	927˙352.20
3	ASKLEPIOS MEDICAL SCHOOL GMBH-AMS  Organization address address: LOHMUHLENSTRASSE 5 HAUS P city: HAMBURG postcode: 20099 contact info Titolo: Ms. Nome: Eniko Ursula Cognome: Holm Email: send email Telefono: 49401800000000 Fax: 49401800000000	DE (HAMBURG)	participant	399˙500.00

Mappa

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 Obiettivo del progetto (Objective)

'The objective of the proposed collaboration research project is the development of a mass spectrometry-based tissue identification system capable of in-vivo, real-time identification of tissues during surgical and diagnostic interventions.

The underlying Rapid Evaporative Ionization Mass Spectrometry (REIMS) method was developed as the first analytical technique allowing the real-time chemical analysis of biological tissues in surgical environment. It was presented two years ago, and since then it was proven to fulfill all expectations raised, regarding level of tissue differentiation. It is now being experimentally tested in human surgical environment and preliminary results indicate that the method provides a real solution for the long-standing problem of instantaneous intraoperative tissue identification. REIMS technique was developed by Medimass Ltd. in close collaboration with Justus-Liebig-Universität, Gießen.

The aim of the project is to develop a device that is capable of utilising REIMS in the surgical environment by adding a number of applications (surgery and targeted cancer types) that provide relevant information to surgeons during operation. In order to prove true intrasurgical applicability for a number of uses, the device interface and the surgical tools have to be adapted and extensively tested in real life situations. The result is a surgical device that is capable of providing instant histology information.

The development of dedicated REIMS instrumentation apart, the proposed project also includes the development of a novel, lipidomics-based tissue phenotyping system, which uses the mass spectrometric data for the establishment of diseased or healthy tissue phenotypes. Envisioned phenotyping is based on the comparison of unknown data to a database of authentic REIMS data by utilizing multivariate statistical pattern recognition algorithms. The results will enable even more detailled analysis therfore result in more precise surgical device.'