SCAFFOLUBE

Lubricated scaffolds for tissue engineering

Coordinatore	WEIZMANN INSTITUTE OF SCIENCE    more Spiacenti, non ci sono informazioni su questo coordinatore. Contattare Fabio per maggiori infomrazioni, grazie.
Nazionalità Coordinatore	Israel [IL]
Totale costo	166˙401 €
EC contributo	149˙999 €
Programma	FP7-IDEAS-ERC Specific programme: "Ideas" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013)
Code Call	ERC-2012-PoC
Funding Scheme	CSA-SA(POC)
Anno di inizio	2013
Periodo (anno-mese-giorno)	2013-03-01   -   2014-02-28

 Partecipanti

#	participant	country	role	EC contrib. [€]
1	WEIZMANN INSTITUTE OF SCIENCE  Organization address address: HERZL STREET 234 city: REHOVOT postcode: 7610001 contact info Titolo: Ms. Nome: Gabi Cognome: Bernstein Email: send email Telefono: +972 8 934 67 28 Fax: +972 8 934 41 65	IL (REHOVOT)	hostInstitution	149˙999.77

Mappa

 Word cloud

Esplora la "nuvola delle parole (Word Cloud) per avere un'idea di massima del progetto.

 Obiettivo del progetto (Objective)

'Osteoarthritis (OA) is a painful joint disorder affecting millions of sufferers worldwide, and occurs through formation oflesions followed by degradation of the articular cartilage layer coating the major joints. Repair of such lesions via tissue engineering has been one of the most promising directions for alleviating OA. The rationale behind this is that the cartilage lesions regenerate after implantation of a scaffolding matrix incorporating desired cell types. Limited clinical success partially originated from the lack of suitable interfacial properties of the scaffolds. We have applied recently revealed concepts on hydration interactions (on some of which we hold a patent), which, we believe, will lead to a significant advance in scaffold-based treatment of cartilage lesions. This applies in particular to the development of scaffolds with modified interfacial properties, which are essential for repairs of large lesions. This is realized by fabricating suitable scaffolds with suitable additives, whose properties form an integral part of our associated ERC project. This Proof of Concept project,which thus ties in closely with our ERC project, consists of several workpackages. An integral part of the plan of work will establish proof of the feasibility of the idea through modification, characterization and mechanical fine-tuning of scaffolds for cartilage compatibility. The other workpackages, which are at the heart of this project, will examine the prospects of commercializing such scaffolds for clinical applications, via multifaceted market studies; identification of possible partners;and development of an appropriate business model.'