JASMONATESTEMCELL

Studies on jasmonate modulation of distal stem cell activity in Arabidopsis root

Coordinatore	VIB    more  Organization address address: Rijvisschestraat 120 city: ZWIJNAARDE - GENT postcode: 9052 contact info Titolo: Mr. Nome: Rik Cognome: Audenaert Email: send email Telefono: +32 9 2446611 Fax: 3292446610
Nazionalità Coordinatore	Belgium [BE]
Totale costo	177˙000 €
EC contributo	177˙000 €
Programma	FP7-PEOPLE Specific programme "People" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013)
Code Call	FP7-PEOPLE-2012-IIF
Funding Scheme	MC-IIF
Anno di inizio	2013
Periodo (anno-mese-giorno)	2013-03-01   -   2015-02-28

 Partecipanti

#	participant	country	role	EC contrib. [€]
1	VIB  Organization address address: Rijvisschestraat 120 city: ZWIJNAARDE - GENT postcode: 9052 contact info Titolo: Mr. Nome: Rik Cognome: Audenaert Email: send email Telefono: +32 9 2446611 Fax: 3292446610	BE (ZWIJNAARDE - GENT)	coordinator	177˙000.00

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 Obiettivo del progetto (Objective)

'Postembryonic root growth of higher plants is maintained by the root meristem (Dolan et al., 1993, Development, 119: 71-84; Weigel and Jürgens, 2002, Nature, 415: 751-754). Our previous studies have highlighted the importance of MYC2-mediated jasmonate signalling in regulating root meristem size by repressing auxin signalling (Chen et al., 2011, Plant Cell, 23: 3335-3352). At the cellular level, we showed jasmonate is capable in disturbing the cellular patterning of the stem cell niche by promoting cell division in quiescent center (QC) and distal stem cell (DSC) differentiation. Maintenance of stem cell activity is crucial for the persistence of postembryonic root growth and many questions on how roots preserve their stem cell niche remain unanswered. Furthermore, nothing is known on how jasmonate signalling interferes with stem cell activity. In this project, we will take profit from the accessibility of the DSC in the Arabidopsis root and will focus our efforts on jasmonate signalling in regulating DSC activity during postembryonic root growth. By DSC specific expression profiling in combination with a comparative analysis of other root specific transcriptome analyses (Birnbaum et al., 2003, Science, 302: 1956-1960; Brady et al., 2007, Science 318: 801-806), we will be able to identify targeted genes involved in jasmonate-regulated DSC differentiation. Genetics tools, cell biology and biochemical techniques will be used to study the mechanisms underlying jasmonate-regulated DSC maintenance. The project will extend our view on how plants retain growth plasticity and on how plants translate stress cues into growth responses. The aim of the fellowship is to add to my knowledge and skills in order to broaden my career prospects in line with the needs of the future knowledge-based agriculture of Europe and the world.'