AGROCOS
From Biodiversity to Chemodiversity: Novel Plant Produced Compounds with Agrochemical and Cosmetic interest
| Coordinatore | NATIONAL AND KAPODISTRIAN UNIVERSITY OF ATHENS
Organization address
address: CHRISTOU LADA 6 contact info |
| Nazionalità Coordinatore | Greece [EL] |
| Totale costo | 4˙271˙584 € |
| EC contributo | 2˙903˙633 € |
| Programma | FP7-KBBE
Specific Programme "Cooperation": Food, Agriculture and Biotechnology |
| Code Call | FP7-KBBE-2009-3 |
| Funding Scheme | CP-FP |
| Anno di inizio | 2010 |
| Periodo (anno-mese-giorno) | 2010-04-01 - 2014-09-30 |
Partecipanti
| # | ||||
|---|---|---|---|---|
| 1 |
NATIONAL AND KAPODISTRIAN UNIVERSITY OF ATHENS
Organization address
address: CHRISTOU LADA 6 contact info |
EL (ATHENS) | coordinator | 706˙753.40 |
| 2 |
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
Organization address
address: Rue Michel -Ange 3 contact info |
FR (PARIS) | participant | 665˙301.60 |
| 3 |
UNIVERSITAET BASEL
Organization address
address: Petersplatz 1 contact info |
CH (BASEL) | participant | 378˙045.00 |
| 4 |
BASF SE
Organization address
address: CARL BOSCH STRASSE 38 contact info |
DE (LUDWIGSHAFEN AM RHEIN) | participant | 308˙690.00 |
| 5 |
KORRES S.A. NATURAL PRODUCTS (KORRES ANONIMI ETERIA FYSIKA PROIONTA)
Organization address
address: 57th Km ATHENS-LAMIA NATIONAL ROAD contact info |
EL (INOFYTA) | participant | 281˙120.00 |
| 6 |
COUNCIL FOR SCIENTIFIC AND INDUSTRIAL RESEARCH
Organization address
address: "Meiring Naude Road, Brummeria 46" contact info |
ZA (PRETORIA) | participant | 210˙243.00 |
| 7 |
BRUKER BIOSPIN GMBH
Organization address
address: Am Silberstreifen contact info |
DE (RHEINSTETTEN) | participant | 172˙800.00 |
| 8 |
"NATIONAL CENTER FOR SCIENTIFIC RESEARCH ""DEMOKRITOS"""
Organization address
address: Patriarchou Gregoriou Str. contact info |
EL (AGHIA PARASKEVI) | participant | 100˙000.00 |
| 9 |
UNIVERSIDAD DE PANAMA
Organization address
address: CALLE MANUEL ESPINOSA BATISTA SN contact info |
PA (Panama) | participant | 80˙680.00 |
Mappa
Word cloud
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Obiettivo del progetto (Objective)
'The consortium will discover and carry to the stage of development candidates, plant derived small molecules with potential as new cosmetic and agrochemical agents. These compounds will derive from plants originating from major biodiversity hotspots in Europe, Africa, Latin America, and the Asia-Pacific region. The starting point of the project will be a diversity-oriented natural product library of 500 compounds from the existing compound repositories of three project partners. Screening of this compound library in assay panels for agrochemical (antifungal, herbicidal, insecticidal) and cosmetic properties (UV-protection, anti-aging, anti-hyperpigmentation) will rapidly identify promising scaffolds. This knowledge will serve as entry points for a chemotaxonomy and chemodiversity oriented collection of plants which are thought to contain structural variants and decorations of these scaffolds. A liquid library of 3600 extracts will be generated and screened. Stringent prioritization and profiling procedures will generate 100 compounds as focused sub-libraries around the privileged scaffolds. A state-of-the-art technology platform for miniaturized natural product discovery will be used for the purpose. Evaluation of these sub-libraries will lead to 30 compounds which will undergo advanced testing to qualify 5 compounds as development candidates for novel agrochemical and/or cosmetic agents with new or improved properties over existing active ingredients. An additional outcome of the project will be an extract library with a unprecedented level of associated spectroscopic information and metadata, to be used for future purposes. The high-caliber consortium brings together international leaders in small molecule natural products, bioprospection, leading industries in agrochemistry, cosmetics, and spectroscopic data management and analysis.'
Introduzione (Teaser)
The European project AGROCOS has sifted through nature's molecules in biodiverse plant collections to extract chemical candidates for the cosmetics and agrochemicals industries.