R'BIRTH
Brain Imaging Return to Health
| Coordinatore | ABO AKADEMI
Organization address
address: DOMKYRKOTORGET 3 contact info |
| Nazionalità Coordinatore | Finland [FI] |
| Totale costo | 4˙214˙310 € |
| EC contributo | 4˙214˙310 € |
| Programma | FP7-PEOPLE
Specific programme "People" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013) |
| Code Call | FP7-PEOPLE-2013-ITN |
| Funding Scheme | MC-ITN |
| Anno di inizio | 2013 |
| Periodo (anno-mese-giorno) | 2013-09-01 - 2017-08-31 |
Partecipanti
| # | ||||
|---|---|---|---|---|
| 1 |
ABO AKADEMI
Organization address
address: DOMKYRKOTORGET 3 contact info |
FI (ABO) | coordinator | 1˙113˙376.44 |
| 2 |
LUNDS UNIVERSITET
Organization address
address: Paradisgatan 5c contact info |
SE (LUND) | participant | 818˙275.48 |
| 3 |
THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN
Organization address
address: College Green - contact info |
IE (DUBLIN) | participant | 731˙116.88 |
| 4 |
Nome Ente NON disponibile
Organization address
address: YLIOPISTONRANTA 1 E contact info |
FI (Kuopio) | participant | 489˙178.80 |
| 5 |
THE UNIVERSITY OF NOTTINGHAM
Organization address
address: University Park contact info |
UK (NOTTINGHAM) | participant | 307˙056.64 |
| 6 |
IMMUNOVIA AB
Organization address
address: MEDICON VILLAGE contact info |
SE (LUND) | participant | 259˙925.16 |
| 7 |
Advanced Practical Diagnostics
Organization address
address: Hertoginstraat 82 contact info |
BE (Turnhout) | participant | 230˙340.00 |
| 8 |
LEIBNIZ-INSTITUT FUER NEUROBIOLOGIE
Organization address
address: BRENNECKESTRASSE 6 contact info |
DE (MAGDEBURG) | participant | 201˙800.72 |
| 9 |
BGI EUROPE INSTITUTE FOND
Organization address
address: OLE MAALOES VEJ 3 contact info |
DK (KOBENHAVN N) | participant | 63˙239.88 |
Mappa
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Obiettivo del progetto (Objective)
'Extended lifespan is a new and permanent feature of human life globally. The demographic for population growth of persons over 60 years is predicted to expand by 70% and 400% respectively in developed and less developed regions during the coming decades. Ageing, is accompanied by cognitive decline and greater risk of depression and anxiety. Major drug companies have recently cutback significantly on development of drugs against brain disorders due to lack of new avenues of research. Thus the responsibility falls on academic labs to make breakthroughs to improve brain health. This consortium gathers experts on molecular mechanisms of age-associated pathologies including depressive disorders and anxiety, and neurodegeneration. Specifically, they focus on identification of stress-regulated molecules provoking neuronal death and hindering neurogenesis, and monitoring the consequences of these processes in human brain. The groups combine biological and medical imaging techniques with behavioral studies and proteomics to define molecular mechanisms of ageing and neurogenesis. Using biotechnology, they will create new tools to isolate neurogenic cells from aged brain, thus aiding research strategies an early stage. Four leading imaging infrastructures from across Europe selected from the ESFRI Eurobioimaging Proof-of Concept list have been selected as partners to facilitate this training and research program. Confocal and high-content imaging is used to define ageing pathways, proteomics and genomics to visualize effectors of pathological ageing, transgenic mice to study neurogenesis and MRI/MRS to identify and localize new depression-related parameters in select patient populations. This multi-faceted approach aims to (i) identify druggable targets and identify reagents to interfere with pathways contributing to depression and anxiety, and (ii) produce novel tools to image depression-associated events in brain, facilitating earlier diagnosis and intervention.'